Next Location Prediction with a Graph Convolutional Network Based on a Seq2seq Framework

( Jianwei Chen ),( Jianbo Li ),( Manzoor Ahmed ),( Junjie Pang ),( Minchao Lu ),( Xiufang Sun ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.5

Predicting human mobility has always been an important task in Location-based Social Network. Previous efforts fail to capture spatial dependence effectively, mainly reflected in weakening the location topology information. In this paper, we propose a neural network-based method which can capture spatial-temporal dependence to predict the next location of a person. Specifically, we involve a graph convolutional network (GCN) based on a seq2seq framework to capture the location topology information and temporal dependence, respectively. The encoder of the seq2seq framework first generates the hidden state and cell state of the historical trajectories. The GCN is then used to generate graph embeddings of the location topology graph. Finally, we predict future trajectories by aggregated temporal dependence and graph embeddings in the decoder. For evaluation, we leverage two real-world datasets, Foursquare and Gowalla. The experimental results demonstrate that our model has a better performance than the compared models.

Exploring lncRNA Expression Patterns in Patients With Hypertrophied Ligamentum Flavum

Junling Chen,Guibin Zhong,Manle Qiu,Wei Ke,Jingsong Xue,Jianwei Chen 대한척추신경외과학회 2024 Neurospine Vol.21 No.1

Objective: Hypertrophy ligamentum flavum (LFH) is a common cause of lumbar spinal stenosis, resulting in significant disability and morbidity. Although long noncoding RNAs (lncRNAs) have been associated with various biological processes and disorders, their involvement in LFH remains not fully understood.Methods: Human ligamentum flavum samples were analyzed using lncRNA sequencing followed by validation through quantitative real-time polymerase chain reaction. To explore the potential biological functions of differentially expressed lncRNA-associated genes, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed. We also studied the impact of lncRNA PARD3-AS1 on the progression of LFH <i>in vitro</i>.Results: In the LFH tissues when compared to that in the nonhypertrophic ligamentum flavum (LFN) tissues, a total of 1,091 lncRNAs exhibited differential expression, with 645 upregulated and 446 downregulated. Based on GO analysis, the differentially expressed transcripts primarily participated in metabolic processes, organelles, nuclear lumen, cytoplasm, protein binding, nucleic acid binding, and transcription factor activity. Moreover, KEGG pathway analysis indicated that the differentially expressed lncRNAs were associated with the hippo signaling pathway, nucleotide excision repair, and nuclear factor-kappa B signaling pathway. The expression of PARD3-AS1, RP11-430G17.3, RP1-193H18.3, and H19 was confirmed to be consistent with the sequencing analysis. Inhibition of PARD3-AS1 resulted in the suppression of fibrosis in LFH cells, whereas the overexpression of PARD3-AS1 promoted fibrosis in LFH cells <i>in vitro</i>.Conclusion: This study identified distinct expression patterns of lncRNAs that are linked to LFH, providing insights into its underlying mechanisms and potential prognostic and therapeutic interventions. Notably, PARD3-AS1 appears to play a significant role in the pathophysiology of LFH.

1,4-Di(3-alkoxy-2-thienyl)-2,5-difluorophenylene: A Building Block Enabling High-Performance Polymer Semiconductors with Increased Open-Circuit Voltages

Chen, Jianhua,Yan, Zhenglong,Tang, Linjing,Uddin, Mohammad Afsar,Yu, Jianwei,Zhou, Xin,Yang, Kun,Tang, Yumin,Shin, Tae Joo,Woo, Han Young,Guo, Xugang American Chemical Society 2018 Macromolecules Vol.51 No.14

<P>A new building block, 1,4-di(3-alkoxy-2-thienyl)-2,5-difluorophenylene (DOTFP) with several desirable features such as high backbone planarity, suitably lying highest occupied molecular orbital (HOMO), and good solubility, was developed by inserting an electron-deficient difluorophenylene into the 3,3′-dialkoxy-2,2′-bithiophene (BTOR) unit. Three regioregular D-A<SUB>1</SUB>-D-A<SUB>2</SUB> type polymers based on DOTFP and benzothiadiazole (BT) derivatives were synthesized and characterized by comparing with a D-A type BTOR-based polymer. The content of highly electron-rich alkoxythiophene is reduced by half in the DOTFP-based polymers versus that of the BTOR-based polymer analogue, which results in a deeper HOMO level and benefits high open-circuit voltage (<I>V</I><SUB>oc</SUB>) in polymer solar cells (PSCs). Consequently, the DOTFP-ffBT-based solar cells exhibited a significantly improved power conversion efficiency (PCE) of 8.7% and an increased <I>V</I><SUB>oc</SUB> of 0.84 V compared to the BTOR-ffBT-based solar cells with a PCE of 2.6% and a <I>V</I><SUB>oc</SUB> of 0.49 V. Additionally, the DOTFP-based polymers showed improved charge transport properties and film morphology than the BTOR-based polymer BTOR-ffBT, resulting in simultaneous enhancement of the short-circuit current (<I>J</I><SUB>sc</SUB>) and fill factor (FF) in PSCs. These results demonstrate the great promise of the DOTFP building block for the construction of high-performance photovoltaic polymer semiconductors with increased <I>V</I><SUB>oc</SUB>s.</P> [FIG OMISSION]</BR>

Reaction kinetics of phenol synthesis through one-step oxidation of benzene with N2O over Fe-ZSM-5 zeolite

Jianwei Li,Guanjie Mi,Jie Zhang,Biaohua Chen 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.6

Based on the information from GC-MS on-line measurement and thermodynamic analysis, the reaction network of gas-phase hydroxylation of benzene with nitrous oxide over Fe-ZSM-5 zeolite was systematically investigated. The main reactions and side reactions were identified, and a kinetic reaction network was proposed as follows:benzene+N2O→phenol→CO/CO2. According to the mechanism, the experimental results were interpreted reasonably. The hydroxylation kinetic experiments were carried out in an isothermal integral microreactor under the conditions of n(benzene)/n(N2O)=8-12, T=663-763 K and atmospheric pressure. Based on the reaction network proposed, the parameters in the rate model of power-law were estimated by means of Gauss-Newton optimal method with the Levenberg-Marquardt modifications, and the results were in good agreement with the experimental data.

Parametric Analysis of End-Plate Joint in Hybrid Strength Steel Frame Subjected to Static Loads

Chen Jia,Jianwei Li,Yongsong Shao,Yongchao Wang 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.6

To achieve the concept of “strong column and weak beam” and further improve the performance of high strength steel frames, the hybrid strength steel frame with the end-plate joint was proposed in this paper. After verifying the FE modeling method, a total of 22 fi ne models were built and the parametric analysis was conducted to investigate the infl uence of eight factors on the initial stiff ness, fl exural capacity and ductility of the joint. The factors included the parameters of the column, the parameters of the end-plate, the parameters of the bolted connection and the compression ratio. The eff ectiveness of these factors was determined by the multivariate regression analysis. Then, the component methods provided in EC3 to determine the fl exural capacity and initial stiff ness were validated. The results indicated that the method for the fl exural capacity was reasonable while the method for the initial stiff ness showed poor accuracy. The formulas to predict the initial stiff ness were modifi ed and were verifi ed.

Multi-level Cross-attention Siamese Network For Visual Object Tracking

Jianwei Zhang,Jingchao Wang,Huanlong Zhang,Mengen Miao,Zengyu Cai,Fuguo Chen 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.12

Currently, cross-attention is widely used in Siamese trackers to replace traditional correlation operations for feature fusion between template and search region. The former can establish a similar relationship between the target and the search region better than the latter for robust visual object tracking. But existing trackers using cross-attention only focus on rich semantic information of high-level features, while ignoring the appearance information contained in low-level features, which makes trackers vulnerable to interference from similar objects. In this paper, we propose a Multi-level Cross-attention Siamese network(MCSiam) to aggregate the semantic information and appearance information at the same time. Specifically, a multi-level cross-attention module is designed to fuse the multi-layer features extracted from the backbone, which integrate different levels of the template and search region features, so that the rich appearance information and semantic information can be used to carry out the tracking task simultaneously. In addition, before cross-attention, a target-aware module is introduced to enhance the target feature and alleviate interference, which makes the multi-level cross-attention module more efficient to fuse the information of the target and the search region. We test the MCSiam on four tracking benchmarks and the result show that the proposed tracker achieves comparable performance to the state-of-the-art trackers.

MR Image Segmentation based on Local Information Entropy Geodesic Active Contour Model

Jianwei Zhang,Xiang Ma,Yunjie Chen,Lin Fang,Jin Wang 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.4

Backbone Conformation Tuning of Carboxylate-Functionalized Wide Band Gap Polymers for Efficient Non-Fullerene Organic Solar Cells

Chen, Jianhua,Wang, Lei,Yang, Jie,Yang, Kun,Uddin, Mohammad Afsar,Tang, Yumin,Zhou, Xin,Liao, Qiaogan,Yu, Jianwei,Liu, Bin,Woo, Han Young,Guo, Xugang American Chemical Society 2019 Macromolecules Vol.52 No.1

<P>Two carboxylate-functionalized wide band gap polymers, 2TC-TT-BDTFT and 2T-TTC-BDTFT, which feature a fluorinated benzodithiophene (BDTFT)-<I>alt</I>-2,5-di(thiophen-2-yl)thieno[3,2-<I>b</I>]thiophene (2T-TT) backbone having different carboxylate attaching positions, were designed and synthesized. By variation of the substitution position of carboxylate groups on the 2T-TT unit, the backbone conformation of the designed building blocks 2TC-TT and 2T-TTC and their corresponding donor-acceptor polymers was fine-tuned as demonstrated by single crystal study and DFT calculation, thus yielding a large device performance difference in organic solar cells. As a result of the relatively higher planarity of the 2T-TTC unit in which the two carboxylate groups were attached on the inner thieno[3,2-<I>b</I>]thiophene moiety, the 2T-TTC-BDTFT polymer exhibited a red-shifted UV-vis absorption, stronger aggregation, and improved charge transport property than its polymer analogue 2TC-TT-BDTFT, in which the two outer thiophene rings were functionalized with carboxylate groups. Benefiting from the improved exciton dissociation and charge collection efficiency, better film morphology, and higher photoresponse, non-fullerene organic solar cells based on 2T-TTC-BDTFT:m-ITIC achieved a power conversion efficiency (PCE) of 11.15% with a fill factor (FF) of ∼70%, while the 2TC-TT-BDTFT:m-ITIC cells showed a relatively lower PCE of 9.65% and FF of 59.31%. The much higher FF of 2T-TTC-BDTFT-based solar cells reflects the great merit of the carboxylation on thienothiophene moiety rather than the outer thiophene counterpart. Therefore, the modulation of the carboxylate position on polymer backbones is an efficient strategy to tune the backbone conformation, interchain packing, film morphology, and the resulting optical, electrical, and photovoltaic properties. Moreover, both the 2T-TTC-BDTFT:m-ITIC and 2TC-TT-BDTFT:m-ITIC solar cells showed excellent stability during annealing and long-term storage. These results demonstrate that carboxylate-functionalized 2T-TTC and 2TC-TT have great potentials as a weak electron-accepting building block for wide band gap polymers for high-performance non-fullerene organic solar cells, and the carboxylate position on the polymer backbones is critical for performance improvement of organic photovoltaic devices.</P> [FIG OMISSION]</BR>

Comments on Special Distillation Processes (Letters to the Editor)

Jianwei Li,Zhigang Lei,Chengyue Li,Biaohua Chen 한국화학공학회 2005 Korean Journal of Chemical Engineering Vol.22 No.4

Clinicopathological Significance of Expression of Tspan-1, Jab1 and p27 in Human Hepatocellular Carcinoma

Li Chen,Daiyue Yuan,Gui-lan Wang,You Wang,Yuan-Yuan Wu,Jianwei Zhu 대한의학회 2010 Journal of Korean medical science Vol.25 No.10

The aim of this study was to investigate the expression of Tspan-1, Jab1 and p27 in human hepatocellular carcinoma (HCC) and their clinicopathological significance. The expression of Tspan-1, Jab1 and p27 was detected in HCC tissues, the tissues around cancer (76 cases),and the normal tissues around the liver hemangiomas (10 cases). The overexpression of Tspan-1 and Jab1 was found in HCC tissues, positively correlated with clinical stage and negatively correlated with survival rate. The expression of p27 was found inversely linked to which of Tspan-1 and Jab1. In conclusion, the expression of Tspan-1, Jab1 and p27 is significantly associated with development of HCC. Overexpression of Tspan-1 and Jab1suggests poor prognosis but overexpression of p27 may expect good prognosis for patients with HCC.