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The effect of spectral entropy monitoring on propofol use and recovery in children
이지연,So Ron Choi,정찬종,이지현,Ji-hye Park,Chang-Yeoul Baik 대한마취통증의학회 2014 Anesthesia and pain medicine Vol.9 No.2
Background: The evaluation of anesthetic depth using electroencephalographyshowed reduction in recovery time from anesthesiaand decrease in the amount of anesthesia used. This researchcompared the dosage of propofol and the recovery characteristicswhen anesthesia was controlled using spectral entropy monitoringand when it was controlled by hemodynamic changes. Methods: Seventy children of the American Society of Anesthesiologistsphysical class I–II, ages 3–10, that were scheduled forgeneral anesthesia were randomly distributed into two groups. Thechildren were sedated with midazolam (0.15 mg/kg), and anesthesiawas induced with fentanyl (2.0 μg/kg), propofol (2.5 mg/kg), androcuronium (0.6 mg/kg). Anesthesia was maintained with propofolcontinuous IV infusion under N2O in O2. For the Entropy Group,the state entropy (SE) was maintained at 40–60, and for theStandard Group, anesthesia was maintained so that the heart rateand systolic blood pressure were at 20% of the standard value. Results: Last 10 minutes of the surgery, the SE and RE (Responseentropy) were significantly higher for the Entropy Group whencompared to the Standard Group (P < 0.05). The maintenancedose of propofol was significantly lower for the Entropy Group whencompared to the Standard Group (P < 0.05). The times takenfor recovery were all significantly shorter for the Entropy Group thanthe Standard Group (P < 0.05). Conclusions: Entropy guided anesthetic administration wasassociated with reduced propofol use and faster recovery in childrencompared to standard practice.
Seon, Ji-Yun,Yoon, Young Joon,Choi, Jaekyoung,Kim, Hyo Tae,Kim, Chang-Yeoul,Kim, Jong-Hee,Baik, Hong Koo American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.11
<P>A dielectophoretic (DEP) device fabricated by a conventional low temperature co-fired ceramic (LTCC) process, for manipulating micro and nanostructure materials, such as spherical polystyrene microspheres, titanium dioxide (TiO2) nanotubes, and silver (Ag) nanowires, is described. To generate a non-uniform electric field, a castellated electrode configuration was applied to the LTCC-based DEP device using a screen printing method. The actual motions of the micro and nanostructure materials under both a positive and a negative DEP force were observed in detail and the findings compared with numerical simulation data for the electric field distribution. The performance of the LTCC-based DEP device for separating and trapping was evaluated and potential applications are discussed.</P>