O Valor Documental dos Balangandãs: Uma Análise Simbólica e Formal The Documental Value of Balangandans: A Symbolic and Formal Analysis

Sura Souza Carmo,Luiz C. Borges 부산외국어대학교 중남미지역원 2021 이베로아메리카 Vol.23 No.1

Systemic and local effects of doxycycline and low-intensity laser treatment on periodontitis in rats

Glauco Rodrigues Carmo Silveira,Daniela Coelho de Lima,Luciano Tavares Ângelo Cintra,Maísa Ribeiro Pereira Lima Brigagão,Edilson Ervolino,Leandro Araújo Fernandes 대한치주과학회 2022 Journal of Periodontal & Implant Science Vol.52 No.1

Purpose: This study evaluated the systemic and local effects of doxycycline (DOX) and lowintensity laser (LIL) treatment as adjuvants to scaling and root planing (SRP) in the treatment of experimental periodontitis in rats. Methods: The sample consisted of 180 male rats (Rattus norvegicus albinus, Wistar), of which 30 did not receive induction of periodontal disease (negative control [NC] group) and 150 received induction of periodontal disease in the lower first molar. After 7 days, the ligature was removed, and the animals were divided into the following groups: NT (no treatment), SRP (SRP), DOX (SRP and DOX irrigation), LIL (SRP and laser irradiation), and DOX+LIL (SRP, DOX, and LIL). The animals were euthanized at 7, 15, and 30 days; thereafter, biochemical, radiographic, histological, and immunohistochemical analyses were performed. Results: In the intragroup analysis, lower concentrations of α-1-glycoprotein acid (α-1-Ga) and complement 3 (C3) were observed in the DOX+LIL group than in all other groups at all time points, as well as lower levels of complement 4 (C4) at 15 and 30 days (P<0.001). Less bone loss was observed in the DOX, LIL, and DOX+LIL groups than in the NC and SRP groups at all time points (P<0.001). There was a smaller number of tartrate-resistant acid phosphatase (TRAP)-positive cells in the DOX+LIL group than in the other groups at all time points (P<0.001). Positive correlations were observed between the systemic levels of α-1-Ga, C3, and C4 and the number of TRAP-positive cells. Conclusions: The combination of DOX with LIL as SRP adjuvants was effective both systemically and locally for the treatment of experimental periodontitis in rats.

Systemic and local effects of doxycycline and low-intensity laser treatment on periodontitis in rats

Silveira, Glauco Rodrigues Carmo,Lima, Daniela Coelho de,Cintra, Luciano Tavares Angelo,Brigagao, Maisa Ribeiro Pereira Lima,Ervolino, Edilson,Fernandes, Leandro Araujo Korean Academy of Periodontology 2021 Journal of Periodontal & Implant Science Vol.51 No.-

Purpose: This study evaluated the systemic and local effects of doxycycline (DOX) and low-intensity laser (LIL) treatment as adjuvants to scaling and root planing (SRP) in the treatment of experimental periodontitis in rats. Methods: The sample consisted of 180 male rats (Rattus norvegicus albinus, Wistar), of which 30 did not receive induction of periodontal disease (negative control [NC] group) and 150 received induction of periodontal disease in the lower first molar. After 7 days, the ligature was removed, and the animals were divided into the following groups: NT (no treatment), SRP (SRP), DOX (SRP and DOX irrigation), LIL (SRP and laser irradiation), and DOX+LIL (SRP, DOX, and LIL). The animals were euthanized at 7, 15, and 30 days; thereafter, biochemical, radiographic, histological, and immunohistochemical analyses were performed. Results: In the intragroup analysis, lower concentrations of α-1-glycoprotein acid (α-1-Ga) and complement 3 (C3) were observed in the DOX+LIL group than in all other groups at all time points, as well as lower levels of complement 4 (C4) at 15 and 30 days (P<0.001). Less bone loss was observed in the DOX, LIL, and DOX+LIL groups than in the NC and SRP groups at all time points (P<0.001). There was a smaller number of tartrate-resistant acid phosphatase (TRAP)-positive cells in the DOX+LIL group than in the other groups at all time points (P<0.001). Positive correlations were observed between the systemic levels of α-1-Ga, C3, and C4 and the number of TRAP-positive cells. Conclusions: The combination of DOX with LIL as SRP adjuvants was effective both systemically and locally for the treatment of experimental periodontitis in rats.

Effect of repair methods and materials on the flexural strength of 3D-printed denture base resin

Hamile Emanuella do Carmo Viotto,Marcela Dantas Dias Silva,Thaís Soares Bezerra Santos Nunes,Sabrina Romão Gonçalves Coelho,Ana Carolina Pero 대한치과보철학회 2022 The Journal of Advanced Prosthodontics Vol.14 No.5

PURPOSE. The aim of this study was to evaluate the flexural strength of a 3D-printed denture base resin (Cosmos Denture), after different immediate repair techniques with surface treatments and thermocycling. MATERIALS AND METHODS. Rectangular 3D-printed denture base resin (Cosmos Denture) specimens (N = 130) were thermocycled (5,000 cycles, 5°C and 55°C) before and after the different repair techniques (n = 10 per group) using an autopolymerized acrylic resin (Jet, J) or a hard relining resin (Soft Confort, SC), and different surface treatments: Jet resin monomer for 180 s (MMA), blasting with aluminum oxide (JAT) or erbium: yttrium-aluminum-garnet laser (L). The control group were intact specimens. A three-point flexural strength test was performed, and data (MPa) were analyzed by ANOVA and Games-Howell post hoc test (α = 0.05). Each failure was observed and classified through stereomicroscope images and the surface treatments were viewed by scanning electron microscope (SEM). RESULTS. Control group showed the highest mean of flexural strength, statistically different from the other groups (P < .001), followed by MMA+J group. The groups with L treatment were statistically similar to the MMA groups (P > .05). The JAT+J group was better than the SC and JAT+SC groups (P < .05), but similar to the other groups (P > .05). Adhesive failures were most observed in JAT groups, especially when repaired with SC. The SEM images showed surface changes for all treatments, except JAT alone. CONCLUSION. Denture bases fabricated with 3D-printed resin should be preferably repaired with MMA+J. SC and JAT+SC showed the worst results. Blasting impaired the adhesion of the SC resin.

Breastfeeding and its Relationship with Reduction of Breast Cancer: A Review

Franca-Botelho, Aline Do Carmo,Ferreira, Marina Carvalho,Franca, Juliana Luzia,Franca, Eduardo Luzia,Honorio-Franca, Adenilda Cristina Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

In this review, we describe the patterns of known immunological components in breast milk and examine the relationship between breastfeeding and reduced risk of breast cancer. The top risk factors for breast cancer are a woman's age and family history, specifically having a first-degree relative with breast cancer. Women that have a history of breastfeeding have been shown to have reduced rates of breast cancer. Although the specific cause has not been elucidated, previous studies have suggested that breastfeeding reduces the risk of breast cancer primarily through two mechanisms: the differentiation of breast tissue and reduction in the lifetime number of ovulatory cycles. In this context, one of the primary components of human milk that is postulated to affect cancer risk is alpha-lactalbumin. Tumour cell death can be induced by HAMLET (a human milk complex of alpha-lactalbumin and oleic acid). HAMLET induces apoptosis only in tumour cells, while normal differentiated cells are resistant to its effects. Therefore, HAMLET may provide safe and effective protection against the development of breast cancer. Mothers should be encouraged to breastfeed their babies because the complex components of human milk secretion make it an ideal food source for babies and clinical evidence has shown that there is a lower risk of breast cancer in women who breastfed their babies.

Bacterial Structure and Characterization of Plant Growth Promoting and Oil Degrading Bacteria from the Rhizospheres of Mangrove Plants

Flávia Lima do Carmo,Henrique Fragoso dos Santos,Edir Ferreira Martins,Jan Dirk van Elsas,Alexandre Soares Rosado,Raquel Silva Peixoto 한국미생물학회 2011 The journal of microbiology Vol.49 No.4

Most oil from oceanic spills converges on coastal ecosystems, such as mangrove forests, which are threatened with worldwide disappearance. Particular bacteria that inhabit the rhizosphere of local plant species can stimulate plant development through various mechanisms; it would be advantageous if these would also be capable of degrading oil. Such bacteria may be important in the preservation or recuperation of mangrove forests impacted by oil spills. This study aimed to compare the bacterial structure, isolate and evaluate bacteria able to degrade oil and stimulate plant growth, from the rhizospheres of three mangrove plant species. These features are particularly important taking into account recent policies for mangrove bioremediation,implying that oil degradation as well as plant maintenance and health are key targets. Fifty-seven morphotypes were isolated from the mangrove rhizospheres on Bushnell-Haas (BH) medium supplemented with oil as the sole carbon source and tested for plant growth promotion. Of this strains, 60% potentially fixed nitrogen, 16% showed antimicrobial activity, 84% produced siderophores, 51% had the capacity to solubilize phosphate, and 33% produced the indole acetic acid hormone. Using gas chromatography, we evaluated the oil-degrading potential of ten selected strains that had different morphologies and showed Plant Growth Promoting Rhizobacteria (PGPR) features. The ten tested strains showed a promising degradation profile for at least one compound present in the oil. Among degrader strains, 46% had promising PGPR potential, having at least three of the above capacities. These strains might be used as a consortium,allowing the concomitant degradation of oil and stimulation of mangrove plant survival and maintenance.

Psychological Risk and Protective Factors for Suicidal Ideation: A Study in an Adolescent Sample in an Insular Context

Ana Margarida Cunha,Cláudia Carmo,Marta Brás 대한소아청소년 정신의학회 2023 소아청소년정신의학 Vol.34 No.4

Objectives: Adolescents are at risk of suicide. As suicide is a multifactorial process, risk and protective factors are relevant constructs for suicide prediction. This study explored the effects of risk and protective factors on suicidal ideation in adolescents on the island of São Miguel (Azores). Methods: A sample of 750 adolescents (male: n=358; 47.7%; mean age=14.67 years; standard deviation=1.85 years) from the island of São Miguel (Azores) completed several measures related to suicidal ideation and associated factors. Using a cross-sectional design, this study conducted descriptive, correlational, predictive, mediation, and moderation analyses. Results: Adolescents generally displayed high levels of risk and protective factors; an indicative proportion exhibited significant suicidal ideation with females presenting the greatest vulnerability. Furthermore, the results highlight that depression is the best predictor of suicidal ideation, however, the association between these variables is mediated. Conclusion: The data corroborate that the suicidal reality of adolescents in the Autonomous Region of the Azores is worrisome. Having substantiated the complexity of the suicidal context in young people in the present research, the need to continue studying risk/protective factors in this area is supported.

Modification of the graphene oxide surface with copper pentacyanonitrosylferrate nanoparticles for electro-oxidation of hydrazine

Maraldi Vitor Alexandre,do Carmo Devaney Ribeiro 한국탄소학회 2021 Carbon Letters Vol.31 No.4

The preparation of graphene oxide and the modifcation of its surface directly with copper pentacyanonitrosylferrate (III) nanoparticles are presented in this work, as well as the characterization of the materials using Fourier-transform infrared spectra, X-ray difractometry and scanning electron microscopy techniques. Beyond that, the study on the electrochemical behavior of the dispersed bimetallic complex on the graphene oxide, as known as GOCuNP, surface was carried out by the cyclic voltammetry technique. The graphite paste electrode modifed with GOCuNP was successfully applied in the detection of hydrazine, presenting limit of detection of 1.58×10–6 mol L−1 at concentration range of 1.00×10–5 to 5.00×10–3 mol L−1 of hydrazine, being so the proposed bimetallic complex formed can be considered as a potential candidate for the manufacturing of electrochemical sensors for hydrazine detection.

Antioxidant Potential of Peels and Fleshes of Peaches from Different Cultivars

Simone B. Rossato,Clarissa Haas,Maria do Carmo B. Raseira,José Cláudio F. Moreira,José Ângelo S. Zuanazzi 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.5

Increasing recent interest in nutraceuticals and functional foods has led researchers to investigate the antioxidant potential of several fruits. This article evaluates the antioxidant potential and reactivity based on luminol-enhanced chemiluminescence capacity of peach extracts (peels and fleshes) and the contribution of a major compound present in these extracts to antioxidant potential and reactivity. The results obtained showed that the extracts of peels and fleshes of Maciel, Leonense, and Eldorado peach cultivars present free radical scavenging activity in all concentrations tested, with a concentration-dependent action. The immediate inhibition of chemiluminescence and the duration of this inhibition were significantly higher with the extracts than with the major compound (chlorogenic acid) alone, and it can be due to a synergistic or additive effect of other antioxidants present in the extracts. The 50% inhibitory concentration (IC50) values for peach extract and chlorogenic acid were 1.19μg/mL and 8.43μg/mL, respectively, when total radical-trapping antioxidant potential was evaluated, whereas IC50 values of 0.41μg/mL and 1.89μg/mL was found when total antioxidant reactivity was evaluated in peach extract and chlorogenic acid, respectively. Chlorogenic acid presented a good contribution to antioxidant reactivity and potential, but the fruit extracts provide better antioxidant action. Peach could be of great interest as an important antioxidant source including chlorogenic acid, and it may provide health-promoting advantages to consumers by intake of this fruit or by utilization of its peels as antioxidant sources in industry.

Composition and Evaluation of the Anti-Inflammatory and Anticancer Activities of the Essential Oil from Annona sylvatica A. St.-Hil

Anelise S.N. Formagio,Maria do Carmo Vieira,Luiz A.C. dos Santos,Clau´dia A.L. Cardoso,Mary Anny Foglio,Joao Ernesto de Carvalho,Magaiver Andrade-Silva,Caˆndida A.L. Kassuya 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.1

The essential oil from the leaves of Annona sylvatica (EOAS) was extracted by hydrodistillation, and the analysis was performed by gas chromatography–mass spectrometry. The main compounds identified in the EOAS were sesquiterpenes, such as hinesol, z-caryophyllene, β-maaliene, γ-gurjunene, silphiperfol-5-en-3-ol, ledol, cubecol-1-epi, and muurola-3,5-diene. Oral administration of the EOAS (20 and 200 mg/kg) and subcutaneous injection of dexamethasone (0.5 mg/kg, reference drug) significantly inhibited carrageenan- and complete Freund's adjuvant–induced mouse paw edema. The anticancer activity the EOAS showed growth inhibitory activity on all cell lines when administered in a high concentration. The EOAS inhibited the growth of human cancer cell lines with GI50 values in the range of 36.04–45.37 μg/mL on all of the cell lines tested. This work describes for the first time the anti-inflammatory and anticancer effects of the essential oil of A. sylvatica and its composition. Considering that drugs currently available for the treatment of inflammatory and cancer conditions show undesirable side-effects, the present results may have clinical relevance and open new possibilities for the development of novel anti-inflammatory and anticancer drugs.