Illudins C_2 and C_3, New Illudin C Derivatives from Coprinus atramentarius ASI20013

LEE, IN-KY0UNG,JEONG, CHEOL-YOUN,CHO, SOO-MUK,YUN, BONG-SIK,KIM, YANG-SUP,YU, SEUNG-HUN,KOSHINO, HIROYUKI,YOO, ICK-DONG 충남대학교 생물공학연구소 1997 생물공학연구지 Vol.5 No.-

Ganoderma lucidum 균주는 인공 배지 상에서 광에 의하여 자실체 원기가 형성되었으며, 광질이 자실체 원기 형성에 미치는 영향을 조사한 결과, 자실체 원기 형성능을 가지고 있는 5균주중 3균주는 공시한 모든 형광등의 아래에서 즉, BLB, 순청색, 순녹색, 순황색, 순적색 형광등의 아래에서 자실체 원기가 형성되었고, 2균주는 BLB 형광등을 제외한 가시광선 영역에서 형성되었다. 그러나 암상태에서는 공시한 모든 균주가 자실체를 형성하지 않았다. 자실체 원기는 광도 0.05에서 10.0 μmol m^-2 s^-1의 범위에서 형성되었고, 광도가 0.5 μmol m^-2 s^-1 이상에서는 자실체 원기의 수가 감소하였다. 주기적인 광조사가 자실체 원기의 형성에 미치는 영향을 조사한 결과, G1-009 균주는 자실체 원기의 수와 무게가 연속광을 조사한 경우보다 증가하였다. 자실체 원기를 형성하기 위해서는 최소 4일간의 광조사가 필요하였다. 단색광의 조사가 자실체 원기의 형성에 미치는 영향을 조사한 결과 G1-003 균주는 400에서 800 nm의 모든 단색광 처리구에서 자실체 원기가 형성되었고, 그 외의 4균주는 400에서 500 nm, 그리고 700에서 750 nm 범위에서 형성되었다. The objective of this research was to determine the effect of light quality on formation of fruit body primordia (FBPs) of Ganoderma lucidum. To achieve this 5 isolates of the fungus that develops fruit body primordia on nutrient agar media were incubated with or without continuous irradiation. The fluorescent lamps used different colors such as black light blue (BLB), pure blue (P-B), pure green (P-G), pure yellow (P-Y) and pure red (P-R). Effect of periodic light and dark exposures on FBP formation of isolate G1-009 was investigated. The FBP formation in G. lucidum isolates was also tested under nomochromatic light produced by the combination of interference filters and colored glass filters. Three isolates produced FBPs under all kinds of fluorescent lamps, whereas two induced FBPs only under visible light except for BLB fluorescent lamp. However, these isolated did not form FBPs in the dark. The FBP was formed at light intensity from 0.05 to 10.0 μmol m^-2 s^-1, and begun to reduce its number as light intensity increase over 0.5 μmol m^-2 s^-1. When the isolate was incubated under periodic light and dark exposures, the number and weight of FBP increased as compared with those under continuous light. Initiation of FBP requires at least 4 days of light illumination. Although isolate G1-003 produced FBPs in a wide range of 400 to 800 nm, other four isolates had two effective regions 400 to 500 nm and 700 to 750 nm in FBP formation.

Ni_1-xFe_x 박막의 자기저항효과에 관한 연구

김종기,정진봉,백주열,이기암 단국대학교 신소재기술연구소 1993 신소재 Vol.3 No.-

DC Magnetron Sputtering 법으로 제조된 Ni_1-xFe_x 박막에 대해 박막의 두께 및 시편의 조성비가 자기저항비에 미치는 영향에 대하여 조사하였다. 시편의 조성비는 Fe chip의 개수로 조정하였으며, 박막의 두께는 400∼1600Å으로 변화시켰다. 복합타겟의 구성방법은 개량된 모자이크방식이었고, 자기저항비는 4-point probe를 이용하여 측정하였다. Fe의 조성이 증가함에 따라서 자기저항비는 증가하였으며, 조성이 x≒11에서 최대가 되었고, 두께가 증가함에 따라 자기저항비도 증가하였다. 제작된 모든 시편은 비정질구조를 나타내었다. We have investigated the magnetoresistance ratio on the influence of film thickness and range of sample composition about Ni_1-xFe_x Thin Film produced by DC Magnetron Sputtering. The range of sample composition was controlled by the number of Fe chips, and the range of deposited film was 400Å to 1600Å. Target formation was the improved mosaic type, and magnetoresistance ratio measured by 4-point probe method. The magnetoresistance ratio was increased with the increase of film thickness, and the magnetoresistance ratio was varied with sample composition. All samples were showed amorphous structure.

Two Newly Recorded Species of Tineidae (Lepidoptera) from Korea

Bong-Woo Lee,Shin-Young Park,Yang-Seop Bae,Bong-Kyu Byun 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.05

The family Tineidae (Lepidoptera), known as fungus moths or tineid moths, contains more than 3,500 species in over 320 genera (Robinson & Nielsen, 1993). It has been known 26 species in 17 genera from Korea (Byun et al., 2009). In this study, two species, Monopis congestella (Walker) and Harmaclona tephrantha (Meyrick), are reported from Korea for the first time. According to Nasu et al. (2008), larvae of M. congestella were founded from nests of Goshawk and Ural Owl and the species distribute South-East Asia and Japan. The genus Harmaclona is known from the Oriental, Ethiopian Regions and the New World but only from China in North-East Asia (Huang, 2010). The adult photos and genitalia illustrations of those two species are provided.

A Clinical Report of Repeated High Fever Treated with Dalwonum

Bong-Ky Park,Chang-Gue Son 대한한의학회 2008 대한한의학회지 Vol.29 No.5

Review for Herbal Drug and Drug-Induced Liver Injury

Bong-Ky Park,Chang-Gue Son 대한한의학회 2010 대한한의학회지 Vol.31 No.3

A Clinical Report of Repeated High Fever Treated with Dalwonum

Park, Bong-Ky,Son, Chang-Gue The Society of Korean Medicine 2008 대한한의학회지 Vol.29 No.5

High fever is a common symptom which is considered an important problem, especially in case of undefined causes. Even though most patients generally have been treated by western medicinal treatments, Oriental medicine has developed some prescriptions having therapeutic efficacy of anti-pyrexia. The present study reports a clinical case of prolonged high fever treated by herbal drug, Dalwonum. There was no specific cause shown by blood test, urinalysis or radiologic test to explain the periodic fever over $40^{\circ}C$, but body temperature slowly started normalize after administration of Dalwonum. This study informed us about the potent usefulness of Dalwonum as an anti-pyrexia herbal drug for patients having fever unresponsive to conventional therapies.

무작위 배정 비교 임상 시험을 통한 국내의 약침 연구에 대한 체계적 고찰

박봉기(Bong-Ky Park),조정효(Jung-Hyo Cho),손창규(Chang-Gue Son) 대한한의학회 2009 대한한의학회지 Vol.30 No.5

한약물을 이용한 암 치료 관련 무작위 배정 임상시험에 대한 고찰

박봉기(Bong-Ky Park),왕경화(Jing-Hua Wang),조정효(Jung-Hyo Cho),손창규(Chang-Gue Son) 대한한의학회 2010 대한한의학회지 Vol.31 No.5

Review for Herbal Drug and Drug-Induced Liver Injury

Park, Bong-Ky,Son, Chang-Gue The Society of Korean Medicine 2010 대한한의학회지 Vol.31 No.3

Objectives: This study aimed to review the general features of drug induced liver injury (DILI) and the important factors in consideration of herbal drugs and DILI. Methods: We reviewed general aspects of DILI such as classification, inducible factors, diagnosis methods, prevention, and the status of herbal drug-associated DILI via literature. Results: Besides the drug itself, genetic and environmental factors affect hepatic toxicity. There is a lack of definitive diagnoses of DILI by drugs, including herbal remedies. The possibility of herbal drug-associated DILI is exaggerated, and majority of herbal drug-derived hepatic injury could be easily prevented if Oriental doctors pay attention to this issue. Conclusion: This study can provide Oriental doctors an overview and be helpful in minimizing the episodes of hepatotoxicity in use of herbal drugs.

Highly CO selective Cu(I)-doped MIL-100(Fe) adsorbent with high CO/CO₂ selectivity due to π complexation: Effects of Cu(I) loading and activation temperature

Vo, The Ky,Bae, Youn-Sang,Chang, Bong-Jun,Moon, Su-Young,Kim, Jeong-Hoon,Kim, Jinsoo Elsevier 2019 Microporous and mesoporous materials Vol.274 No.-

<P><B>Abstract</B></P> <P>Cu(I) doping of octahedral MIL-100(Fe) was successfully performed by means of impregnation and consequent reduction under vacuum conditions. Although MIL-100(Fe) adsorbed CO<SUB>2</SUB> better than CO, Cu(I)@MIL-100(Fe) showed selective CO adsorption compared to CO<SUB>2</SUB> owing to π complexation between CO and Cu(I). Effects of Cu(I) loading concentration, activation temperature, and adsorption temperature upon CO/CO<SUB>2</SUB> adsorption properties were systematically investigated. The adsorption behaviors of CO and CO<SUB>2</SUB> on MIL-100(Fe) and Cu(I)@MIL-100(Fe) were well described by the dual-site Langmuir–Freundlich (DSLF) model. Ideal adsorbed solution theory (IAST) was used to predict adsorption isotherms of equimolar CO and CO<SUB>2</SUB> mixtures and to predict CO/CO<SUB>2</SUB> selectivities as a function of bulk pressure. The obtained results showed that 45 wt% Cu(I)-doped MIL-100(Fe) had CO adsorption capacity of 3.10 mmol g<SUP>−1</SUP> and CO/CO<SUB>2</SUB> selectivity of 420 at 298 K and 1 bar. In addition, a large CO working capacity of 1.39 mmol g<SUP>−1</SUP> was observed for 45 wt% Cu(I)-doped MIL-100(Fe) in the pressure range of 10–100 kPa. Cu(I)-doped MIL-100(Fe) thus appears promising as an adsorbent material for effective CO/CO<SUB>2</SUB> separation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cu(I) was doped onto MIL-100(Fe) for highly selective adsorption of CO compared to CO<SUB>2</SUB>. </LI> <LI> The effects of metal loading, activation temperature, and adsorption temperature were investigated. </LI> <LI> Cu(I)@MIL-100(Fe) exhibited the high CO adsorption capacity of 3.10 mmol g<SUP>−1</SUP>. </LI> <LI> The IAST prediction of CO/CO<SUB>2</SUB> selectivity was 420 at 298 K and 1 bar. </LI> <LI> The CO working capacity of 1.39 mmol g<SUP>−1</SUP> was obtained for 45Cu(I)@MIL-100(Fe). </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>