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Development of Coating Process Technique for Anti-Fouling Electric Insulator
Shan, Bo Wen,Choi, In Hyuk,Kim, Jung Hyun,Choi, Won Seok Trans Tech Publications, Ltd. 2017 Materials science forum Vol.904 No.-
<P>In order to improve the anti-fouling characteristics of the electric insulator for electric railway, a functional coating for preventing pollution was carried out on the surface of the T type post insulator and long rod insulator in the railway insulators. In order to ensure the durability of the thin film on the coated insulator surface, the coating was annealed at three different annealing cases by using a furnace. Case 1 is annealing treatment at 250°C and case 2 is annealing treatment at 400°C. Case 3 is the double annealing treatment (case 1 + case 2). The film Surface conductivity and anti-fouling characteristics of the insulators annealed at three temperature conditions were measured. It was confirmed that the insulator annealed in case 3 had both good conductivity and anti-fouling characteristics.</P>
Contact toxicity and transcriptomic analysis of terpinen-4-ol exposure in Tribolium castaneum
Shan-shan Gao,Yong-lei Zhang,Kun-peng Zhang,Wang Xing-yun,Qing-bo Tang,Yuan-chen Zhang 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.3
The terpene, terpinen-4-ol (T4ol), exhibits contact toxicity in Tribolium castaneum. However, the molecular mechanisms underlying this toxicity have not been elucidated. This study examined changes in the expression of four classic enzymes after exposure of T. castaneum to T4ol. Acetylcholinesterase and glutathione S-transferase activities were markedly inhibited after exposure to T4ol, while that of the detoxifying enzyme cytochrome oxidase P450 increased markedly. Carboxylesterase activity did not show significant changes. Furthermore, RNA sequencing revealed 260 differentially expressed genes (DEG) between the T4ol-treated and control samples, and qRT-PCR was used to validate the RNA-Seq data. The Gene Ontology analysis classified the DEGs into 36 functional groups, including the immune system processes, response to stimulus, and developmental processes. T4ol altered the response to stimulus and the immune system process of beetles by inducing the expression of the genes Stabilin-1, Attacin 1, and Defensin 1. Furthermore, the DEGs receptor tyrosine kinase Torso-like protein (RTKTsl), Frizzled 4 (Fz4), Protein Wnt-5b, Ecdysone-induced protein 78C (E78), Zinc finger protein GLIS1 (ZFPGLIS1) were classified as participating in beetle development, and Fz4 and Protein Wnt-5b also mapped to the Wnt signaling pathway. This indicated that pathways associated with development are inhibited after exposure to T4ol. T4ol also induced CYP9Z6/GSTs7 overexpression, and RNAi targeting these genes significantly increased larvae mortality on T4ol exposure, supporting the participation of CYP9Z6/GSTs7 in the response to T4ol in T. castaneum. The results of this study will facilitate understanding of the toxic mechanisms of T4ol and provide a basis for controlling the pests of stored products.
SINGLE MACHINE GROUP SCHEDULING UNDER DECREASING LINEAR DETERIORATION
Wang, Ji-Bo,Guo, Ai-Xia,Shan, Feng,Jiang, Bo,Wang, Li-Yan 한국전산응용수학회 2007 Journal of applied mathematics & informatics Vol.24 No.1
This paper considers single machine scheduling problems with group technology (GT) and deteriorating jobs. A sequence independent setup is required to process a job from a different group and jobs in each group are processed together. We consider the case of jobs whose processing times are a decreasing function of their starting time. The objectives of scheduling problems are to minimize the makespan and the total completion time, respectively. We also provide polynomial time algorithms to solve these problems.
The role of protein arginine-methyltransferase 1 in gliomagenesis
( Shan Wang ),( Xiao Chao Tan ),( Bin Yang ),( Bin Yin ),( Jian Gang Yuan ),( Bo Qin Qiang ),( Xiao Zhong Peng ) 생화학분자생물학회(구 한국생화학분자생물학회) 2012 BMB Reports Vol.45 No.8
Protein arginine methyltransferase 1 (PRMT1), a type-I arginine methyltransferase, has been implicated in diverse cellular events. We have focused on the role of PRMT1 in gliomagenesis. In this study, we showed that PRMT1 expression was up-regulated in glioma tissues and cell lines compared with normal brain tissues. The knock-down of PRMT1 resulted in an arrest in the G1-S phase of the cell cycle, proliferation inhibition and apoptosis induction in four glioma cell lines (T98G, U87MG, U251, and A172). Moreover, an in vivo study confirmed that the tumor growth in nude mouse xenografts was significantly decreased in the RNAi-PRMT1 group. Additionally, we found that the level of the asymmetric dimethylated modification of H4R3, a substrate of PRMT1, was higher in glioma cells than in normal brain tissues and decreased after PRMT1 knock-down. Our data suggest a potential role for PRMT1 as a novel biomarker of and therapeutic target in gliomas. [BMB Reports 2012; 45(8): 470-475]
Bo Bi,Liping Shan,Die Zhou 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.1
Patients with urologic chronic pelvic pain syndromes (UCPPS) report interstitial cystitis/bladder pain syndrome and/or chronic prostatitis/chronic pelvic pain syndrome. The pathogenesis of these syndromes remains unclear and there is currently no standard treatment. UCPPS is, therefore, often misdiagnosed and its management is complex. The present case report involves a 62-year-old male patient with UCPPS whose main presentation is painful bladder filling and painful urgency refractory to conventional treatment with medication, which was successfully treated with the combined use of duloxetine and olanzapine. The combined use of duloxetine and olanzapine may become a new therapeutic option in the management of UCPPS.
Bo Shu,Shan Lu,Haiju Hu 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.11
With the development of cloud computing, big data, Internet of things, the traditional logistics industry integration of the Internet. It gave birth to a variety of business models and Shared prosperity. It has discovered the dynamic factors of logistics industry in Jing-Jin-Ji region (Beijing, Tianjin and Hebei region) were related to the regional network, industry integration and business innovation, etc. This article, based on the investigation of "the networked logistics industry" in Beijing, Tianjin, Hebei, influence elements of logistics industry,established the model of combination of the dynamics.The model reflected the network in the process of logistics industry,which including four dimensions :the logistics industry benefit, scale of logistics, the logistics demand and logistics network resources, to simulate the trend of the logistics industry network. In addition, It observed the dynamic effect of the four-dimensional one completely changed. It has been found that the influence of scale of logistics efficiency and logistics more network logistics industry in Jing-Jin-Ji. But it is not obvious, the influence of the network resources, the logistics demand of network logistics industry in Jing-Jin-Ji area.
Shan Gao,Bo Yang,Lanhui Guo,Man Xu,Feng Fu 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.42 No.2
In this paper, four specimens of CFST column joints with endplates and long bolts are tested in the scenario of progressive collapse. Flush endplate and extended endplate are both adopted in this study. The experimental results show that increasing the thickness of the endplate could improve the behavior of the joint, but delay the mobilization of catenary action. The thickness of the endplate should not be relatively thick in comparison to the diameter of the bolts, otherwise catenary action would not be mobilized or work effectively. Effective bending deformation of the endplate could help the formation and development of catenary action in the joints. The performance of flexural action in the joint would affect the formation of catenary action in the joint. Extra middle-row bolts set at the endplates and structural components set below the bottom beam flange should be used to enhance the robustness of joints. A special weld access hole between beam and endplate should be adopted to mitigate the chain damage potential of welds. It is suggested that the structural components of joints should be independent of each other to enhance the robustness of joints. Based on the component method, a formula calculating the stiffness coefficient of preloaded long bolts was proposed whose results matched well with the experimental results.