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Detection Rate of Prostate Cancer on the Basis of the Vienna Nomogram: A Singapore Study
Jin Kiat Teo,Beow Kiong Poh,Foo Cheong Ng,Yan Kit Fong 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.4
Purpose: The purpose of this study was to determine the efficacy of the Vienna nomogramprostate biopsy model in the detection of prostate cancer in our local population. We also assessed the incidence of complications from using such a template. Materials and Methods: From January 2006 to June 2007, 120 men with either elevatedprostate-specific antigen (PSA) scores (>4 ng/mL) and/or abnormal digital rectal examinationwere enrolled prospectively to undergo extraction of 6 to 18 cores for transrectalultrasound-guided prostate biopsy, as indicated by the Vienna nomogram. Results: The mean age was 62.6±8.3 years (range, 40–86 years). The mean PSA scorewas 13.42 ng/mL. The mean number of cores obtained was 9.68±3.1. According to theVienna nomogram, 27 out of a total of 120 patients had prostate cancer, for a detectionrate of 22.5%. In the group of patients with PSA scores <10 ng/mL, the detection ratewas 14.9% (14 of 94 patients). The group of patients with PSA scores >10 ng/mL hada detection rate of 50% (13 of 26). The complication rate in our study was 7.5%. Conclusions: With the use of the Vienna nomogram, our prostate cancer detection rateis comparable to previously published data for Asian patients. This nomogram offersan easy tool with which to select the optimal number of prostate biopsy cores to be takenon the basis of patient age and total prostate volume. With this biopsy strategy, we alsohave found that the complication rate from prostate biopsy is low.