INDEPENDENT TRANSVERSAL DOMINATION NUMBER IN COMPLEMENTARY PRISMS

( Aysun Aytaç ),( Cem Erkal ) 호남수학회 2021 호남수학학술지 Vol.43 No.1

A set D ⊆ (G) is an independent transversal dominating set of G if D is a dominating set and also intersects every maximum independent set in G. The minimum cardinality of such a set is equal to the transversal domination number, denoted by □it(G). This paper is devoted to the computation of the independent transversal domination number of some complementary prism.

Small State Intelligence: New Zealand in SEATO Security Affairs

İ. Aytaç Kadıoğlu,Egemen B. Bezci 인하대학교 국제관계연구소 2020 Pacific Focus Vol.35 No.1

This article aims to shed light on how and why small states enter into cooperation alliances with greater powers. It does so by assessing the intelligence and security cooperation activities of New Zealand in the Pacific basin as a small state during the Cold War era. It also assesses its relationships with the United Kingdom (UK) and the United States, as well as its role within the Southeast Asia Treaty Organization (SEATO), an understudied international organization operating for collective defense. The article offers a threefold analysis involving financial costs, the quest for shelter and diversification. It argues that New Zealand utilized its alliance relationships with SEATO members to seek shelter and gain information with limited expenditure and less effort. Using original data from the archives of New Zealand and the UK, the article reveals that New Zealand's foreign and security policy commitments in the Pacific were shaped by the country's geographical remoteness and the limitations of its diplomatic capacity.

Effect of Type 2 Diabetes Mellitus on Prognosis of Nonmetastatic Renal Cell Cancer

Evren Süer,Erdem Öztürk,Ömer Gülpınar,Aytaç Kayış,Sümer Baltacı 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.8

Purpose: We evaluated the prognostic value of type 2 diabetes mellitus (DM) in patients treated surgically for localized renal cell carcinoma (RCC). Materials and Methods: Between 1995 and 2011, 588 patients with renal tumor diagnoses were treated surgically and 492 patients with pathologically confirmed nonmetastatic RCC diagnoses were included in the study. The associations of clinical and pathologic parameters with a type 2 DM diagnosis were evaluated. Kaplan-Meier estimations for disease-specific survival (DSS) and overall survival (OS) were generated according to type 2 DM diagnosis, and the log-rank test was used to compare survival according to the variables. Results: The mean age of the patients was 56.7±12 years (range, 15 to 84 years; median, 58 years) and the mean length of follow-up was 35.9±28 months (range, 1 to 145 months; median, 34.3 months). Of the 492 patients, 62 (12.6%) had a diagnosis of DM at the time of surgery (group I) and 430 did not have DM (group II). The mean age and the incidence of clear cell RCC histological subtype were significantly higher in group I than in group II (p<0.001 and p=0.036, respectively). Although DSS and OS were lower in group I, this difference was not significant. Type 2 DM was not detected as an independent prognostic factor for DSS and OS. Conclusions: This study investigated the role and effect of DM on the prognosis of localized RCC that was treated surgically. The present study did not detect DM as an independent prognostic factor for RCC.

Improving the diagnosis of high grade and stage bladder cancer by detecting increased urinary calprotectin expression in tumor tissue and tumor-associated inflammatory response

Yusuf Sahin,Ugur Yucetas,Huseyin Aytaç Ates,Erkan Erkan,Esma Yucetas,Mustafa Zafer Temiz,Mahmut Gokhan Toktas,Mustafa Kadihasanoglu,Birsen Cigdem Topkaya 대한비뇨의학회 2019 Investigative and Clinical Urology Vol.60 No.5

Purpose: To investigate whether measurement of urinary calprotectin can serve as a biomarker in the diagnosis of primary bladder cancer and to confirm its diagnostic role in determining high grade and stage disease. Materials and Methods: Urinary calprotectin was measured in spot urine samples from patients with primary bladder cancer and control subjects. To confirm levels in urine, tissue samples were also obtained from bladder tumor and healthy trigone of bladder by transurethral resection in both groups. Finally, calprotectin levels in tissue and urine of the patients and control subjects were compared and their diagnostic potential was investigated in high grade and stage bladder cancers. Results: Of 82 participants, 52 were patients with bladder cancer and 30 were control subjects. The two groups were comparable in terms of age, smoking status, and comorbidities. Tissue and urinary calprotectin levels were significantly higher in the bladder cancer group. In subgroup analyses, urinary calprotectin levels were significantly higher in patients with high-grade, muscle-invasive tumors. After receiver operating characteristic analyses, the sensitivity and specificity of urinary calprotectin was 100% and 96.7%, respectively, in the diagnosis of primary bladder cancer. High grade and stage bladder cancers were detected with sensitivity and specificity of 70% and 74.2%, and 80% and 84.8%, respectively. Conclusions: Urinary calprotectin may be a valuable parameter in the diagnosis of primary bladder cancer with high sensitivity and specificity. Furthermore, it may be useful in the prediction of high grade and stage disease. However, more investigations are needed.

Evaluating the effect of donor anxiety levels and lifestyle characteristics on the activation of platelet concentrates

Soner Yılmaz,İbrahim Eker,Elif Elçi,Aysel Pekel,Rıza Aytaç Çetinkaya,Aytekin Ünlü,Cengizhan Açıkel,İsmail Yaşar Avcı 대한혈액학회 2019 Blood Research Vol.54 No.4

BackgroundSmoking, alcohol use, performing regular physical exercise, dietary habits, and anxiety level may cause platelet activation. We aimed to evaluate the anxiety levels, smoking sta-tus, alcohol intake, and sportive habits of donors, and determine their impact on the qual-ity of apheresis-platelets.MethodsState and Transient Anxiety Inventory (STAI) was used to determine the level of donors’anxiety. STAI has two subscales: S-anxiety scale (STAI-I) and T-anxiety scale (STAI-II), each comprising 20 questions rated on a 4-point Likert scale. Data on smoking, alcohol con-sumption, and performing regular physical exercise were obtained from a questionnaire filled out before donation. Flow cytometric analysis was used to quantify activated platelets.ResultsThe STAI-I level of 86 participants was normal, while that of 12 was higher. No significant difference was found in the active platelet absolute count [1.8×1011 (2.7) and 1.4×1011 (1.3), respectively; P=0.665] between donors with normal STAI-I levels and those with higher STAI-I levels. Of 98 donors, 42 had normal STAI-II levels, while 56 had higher STAI-II levels. No significant difference was found in the active platelet absolute count [2.3×1011 (3.1) and 1.5×1011 (2.3), respectively; P=0.224] between donors with normal STAI-II levels and those with higher STAI-II levels. Platelet counts of individuals who perform regular physical exercise were significantly higher than those of individuals who did not perform regular physical exercise (6.3±1.4×1011 vs. 5.5±1.4×1011).ConclusionThe quality of apheresis platelets is not affected by anxiety levels and lifestyle character-istics of blood donors. There is no need to organize apheresis blood donor pool consider-ing with these subjects.

Anorexigenic peptide (leptin, obestatin, nesfatin-1) levels and their impact on assisted reproductive technology treatment outcomes in patients with polycystic ovary syndrome

Bulut Varlı,Yavuz Emre Şükür,Batuhan Özmen,Berrin İmge Ergüder,Sönmezer Murat,Berker Bülent,Atabekoğlu Cem Somer,Aytaç Ruşen 대한생식의학회 2021 Clinical and Experimental Reproductive Medicine Vol.48 No.4

Objective: In this study we aimed to assess anorexigenic peptide levels in patients with or without polycystic ovary syndrome (PCOS) and their effects on assisted reproductive treatment (ART) outcomes. Methods: A prospective case-control study was conducted in a tertiary care university-based ART clinic. Eighty-three patients were included in the study. The PCOS group included 41 patients, and the non-PCOS group included 42 controls. The 2003 Rotterdam criteria were used for PCOS patient selection. The ART indications in the non-PCOS group were tubal factor or unexplained infertility. Venous blood samples were taken on the third day of the menstrual cycle to determine the serum anorexigenic peptide levels. The enzyme-linked immunosorbent assay method was used for laboratory analyses. Results: In the PCOS group, serum obestatin levels were significantly lower than in the control group, but serum anorexigenic peptide levels were similar in PCOS patients with or without clinical pregnancy. Ovarian hyperstimulation syndrome (OHSS) was diagnosed only in PCOS patients, and the obestatin levels of OHSS patients were significantly lower than those of other PCOS patients. Conclusions: Baseline anorexigenic peptide levels did not affect the clinical pregnancy rate in ART cycles. Obestatin may play a role in the pathophysiology of OHSS; this possibility should be confirmed in further research.

Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches

Zygogianni, Anna G.,Kyrgias, George,Gennatas, Costantinos,Ilknur, Aytas,Armonis, Vassilios,Tolia, Maria,Papaloukas, Christos,Pistevou, Gompaki,Kouvaris, John,Kouloulias, Vassilios Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

Male breast cancer is a very rare disease with an incidence of about 0.5-1% comparing with the one of female breast cancer but relatively little is known about its cause. Treatment strategies for breast cancer in males are derived from studies performed among females. The probable reasons behind the frequent, late diagnoses presented at stages III or IV might be the lack of awareness. The rarity of the disease precludes large prospective randomized clinical trials. This study reviews male breast cancer and its risk factors, recommendations for diagnosis and the management of patients with male breast cancer.