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        Lactobacillus fermentum strains from human breast milk with probiotic properties and cholesterol-lowering effects

        Meltem Asan-Ozusaglam,Ayse Gunyakti 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.2

        The study aimed to identify two lactic acidbacteria from human breast milk and evaluate for theirprobiotic potential. Lactobacillus fermentum strainsshowed various degree of antibiotic susceptibility profile toclinical commercial antibiotics. The MA-7 and MA-8strains have never lost their vitality at pH 2 and 3. Lactobacillusfermentum MA-8 exhibited more resistance to 0.3and 1% bile concentrations than MA-7 strain. Both of theL. fermentum strains can tolerate the simulated gastric andintestinal juices. The strains showed high auto-aggregationpercentages varied from 95 to 98%. Both isolates alsoexhibited gamma hemolytic activity. The cholesterol loweringactivity of MA-7 and MA-8 strains was varied from34.84 to 91.15%. The supernatants showed higher anticholesterolactivity compared to pellets. The resultsdemonstrated that both L. fermentum strains maybe goodprobiotic candidates and may have potential as healthbiotherapeutic with cholesterol-lowering effects.

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