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RISS 인기검색어
- 검색키워드
- 저자 : Aydin Gullu (검색결과 2 건)
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EFFECT OF BUMPER THICKNESS WITH COLLISION SIMULATION OF PASSENGER VEHICLES
Ferhat Özcan,Aydin Gullu,Sezgin Ersoy 한국자동차공학회 2023 International journal of automotive technology Vol.24 No.1
The finite element method is the most common method used to solve engineering and mathematical model problems. Related solution areas include structural analysis, heat transfer, mass transport and electromagnetic potential. FEM is a specific numerical method used to solve partial differential equations in two or three space variables. To solve a problem, FEM breaks up a large system into smaller, simpler parts called finite elements. First, a three-dimensional model of the system to be analyzed is produced. While defining the model, the materials and connection types found in the model are also deter-mined. Afterwards, the model is divided into small parts and analyzed under specified conditions. A crash test will be conducted in this study. For this, the conditions of the vehicle parts will be examined by hitting a wall under the conditions of which the model design of the vehicle is determined. Crash tests were carried out for two different bumper thicknesses on the same vehicle and the test results were examined. The vehicle speed is modeled as 20 m/s in the simulation carried out from the moment of impact until 0.14 seconds later. The effect of buffer thickness on axial displacements at impact and energy changes are presented.
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Koldemir-Gunduz, Meliha,Aydin, Hasan Emre,Berikten, Derya,Kaymak, Gullu,Kose, Dursun Ali,Arslantas, Ali The Korean Neurosurgical Society 2021 Journal of Korean neurosurgical society Vol.64 No.6
Objective : The aim of our study is to investigate the cytotoxic, antioxidant, and antimicrobial effects of newly synthesized boron compounds in U87MG glioblastoma cell treatment. Methods : We synthesized boron glycine monoester (BGM) and boron glycine diester (BGD) structures containing boron atoms and determined their cytotoxic activities on glioblastoma by the MTT method. The inhibitory concentration 50 (IC<sub>50</sub>) value was calculated with GraphPad Prism 5.0 program. The IC<sub>50</sub> values were administered 48 hours on U87MG glioblastoma cell. Catalase (CAT), acid phosphatase (ACP) and alkaline phosphatase (ALP) enzyme activity, malondialdehyde (MDA), total glutathione (GSH), and total protein levels were detected using spectrophotometric methods. We determined the antimicrobial activities of BGM and BGD with the disc diffusion method. Results : After 48 hours of BGM and BGD application to U87MG glioblastoma cells, we found the IC<sub>50</sub> value as 6.6 mM and 26 mM, respectively. CAT and ACP enzyme activities were decreased in BGM and BGD groups. MDA which is a metabolite of lipid peroxidation was increased in both boron compounds groups. GSH level was reduced especially in BGD group. BGM and BGD have been found to be antimicrobial effects. Conclusion : Boron compounds, especially the BGM, can provide a new therapeutic approach for the treatment of glioblastoma with their anticancer, antioxidant, and antimicrobial effects.
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