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- 저자 : Ashtiani (검색결과 41 건)
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Ashtiani, Zahra Ousati,Heidari, Mansour,Hasheminasab, Sayed-Mohammad,Ayati, Mohsen,Rakhshani, Naser Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
In this study mitochondrial D-Loop variations in Iranian prostate cancer and benign prostatic hyperplasia (BPH) patients were investigated. Tumour samples and corresponding non-cancerous prostate tissue from 40 prostate cancer patients and 40 age-matched BPH patients were collected. The entire mtD-loop region (16024-576) was amplified using the PCR method and products were gel-purified and subjected to direct nucleotide sequencing. A total of 129 variations were found, the most frequent being 263A${\rightarrow}$G and 310T${\rightarrow}$C among both BPH and prostate cancer patients. Variation of 309 C${\rightarrow}$T was significantly more frequent in prostate cancer patients (P value<0.05). Four novel variations were observed on comparison with the MITOMAP database. Novel variations were np16154delT, np366G${\rightarrow}$A, np389G${\rightarrow}$A and 56insT. There was no correspondence between the different variations and the age of subjects. Considering that D-loop variations were frequent in both BPH and prostate cancer patients in our study, the fact that both groups had high average age can be a possible contributing factor. D-loop polymorphisms and microsatellite instability can influence cell physiology and result in a benign or malignant phenotype. Significantly higher frequency of 309 C${\rightarrow}$T variation in cancer patients is a notable finding and must be a focus of attention in future studies.
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Ashtiani-Araghi, Alireza,Lee, Chungu,Cho, Seong-In,Rhee, Joong-Yong Korean Society for Agricultural Machinery 2015 바이오시스템공학 Vol.40 No.1
Purpose: To present a flexible and accurate autonomous solution for creating any desired row spacing value between the hydroponic gullies in multilayer growing units, and evaluate the capabilities and performance of the relevant automated system through the use of virtual prototyping technique. Methods: To build the virtual prototype of the system, CAD models of its different parts, including an autonomous vehicle and the mechanical mechanisms embedded in the multilayer growing unit, were developed and imported into the RecurDyn simulation software. In order to implement the automated row spacing operation, three spacing modes with different loading cycles and working steps were defined, and the operation of the system was simulated to obtain the target row spacing values specified for each of these modes. Results: Motion profiles related to the horizontal displacement of: 1) the lower and upper sliding bars installed in the cultivation layers, and 2) the hydroponic gullies, during the simulation of the system operation, were generated and analyzed. No deviation from the specified target spacing values was observed at the end of simulations for all spacing modes. Conclusions: The results of the motion analysis obtained by simulating the system operation confirm the effectiveness of the control scheme proposed for automated row spacing of gullies. It was also found that proper sequencing of the loading cycles and the precision of the working strokes of the upper bars are the critical factors for establishing a certain row spacing value. Based on the simulation results, precise control of the back and forth motions of the upper bars is highly necessary for sound operation of the real system.
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( Alireza Ashtiani Araghi ),( Chun Gu Lee ),( Seong In Cho ),( Joong Yong Rhee ) 한국농업기계학회 2015 바이오시스템공학 Vol.40 No.1
Purpose: To present a flexible and accurate autonomous solution for creating any desired row spacing value between the hydroponic gullies in multilayer growing units, and evaluate the capabilities and performance of the relevant automated system through the use of virtual prototyping technique. Methods: To build the virtual prototype of the system, CAD models of its different parts, including an autonomous vehicle and the mechanical mechanisms embedded in the multilayer growing unit, were developed and imported into the Recur Dyn simulation software. In order to implement the automated row spacing operation, three spacing modes with different loading cycles and working steps were defined, and the operation of the system was simulated to obtain the target row spacing values specified for each of these modes. Results: Motion profiles related to the horizontal displacement of: 1) the lower and upper sliding bars installed in the cultivation layers, and 2) the hydroponic gullies, during the simulation of the system operation, were generated and analyzed. No deviation from the specified target spacing values was observed at the end of simulations for all spacing modes. Conclusions: The results of the motion analysis obtained by simulating the system operation confirm the effectiveness of the control scheme proposed for automated row spacing of gullies. It was also found that proper sequencing of the loading cycles and the precision of the working strokes of the upper bars are the critical factors for establishing a certain row spacing value. Based on the simulation results, precise control of the back and forth motions of the upper bars is highly necessary for sound operation of the real system.
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Effect of Foliar and Root Application of Silicon Against Rice Blast Fungus in MR219 Rice Variety
Abed-Ashtiani, Farnaz,Kadir, Jugah-Bin,Selamat, Ahmad-Bin,Hanif, Ahmad Husni Bin-Mohd,Nasehi, Abbas The Korean Society of Plant Pathology 2012 Plant Pathology Journal Vol.28 No.2
Rice blast disease caused by Magnaporthe grisea (Hebert) Barr [teleomorph] is one of the most devastating diseases in rice plantation areas. Silicon is considered as a useful element for a large variety of plants. Rice variety MR219 was grown in the glasshouse to investigate the function of silicon in conferring resistance against blast. Silica gel was applied to soil while sodium silicate was used as foliar spray at the rates of 0, 60, 120, 180 g/5 kg soil and 0, 1, 2, 3 ml/l respectively. The treatments were arranged in a completely randomized design. Disease severity and silicon content of leaves were compared between the non-amended controls and rice plants receiving the different rates and sources of silicon. Silicon at all rates of application significantly (${\alpha}$ = 0.05) reduced the severity of disease with highest reduction (75%) recorded in treatments receiving 120 g of silica gel. SEM/EDX observations demonstrated a significant difference in weight concentration of silicon in silica cells on the leaf epidermis between silicon treated (25.79%) and non treated plants (7.87%) indicating that Si-fertilization resulted in higher deposition of Si in silica cells in comparison with non-treated plants. Application of silicon also led to a significant increase in Si contents of leaves. Contrast procedures indicated higher efficiency of silica gel in comparison to sodium silicate in almost all parameters assessed. The results suggest that mitigated levels of disease were associated with silicification and fortification of leaf epidermal cells through silicon fertilization.
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( Elaheh Miri Ashtiani ),( Nasim Shokouhi ),( Mona Mohseni ),( Nafiseh Saedi ),( Ali Asghar Haeri-mehrizi ),( Mahmood Bakhtiyari ) 대한산부인과학회 2023 Obstetrics & Gynecology Science Vol.66 No.3
Objective The current study aimed to compare the effectiveness of novel radiofrequency modulation (RM) therapy with a tailored physiotherapy course for patients with chronic pelvic pain (CPP) of myofascial origin, also known as myofascial pelvic pain syndrome (MPPS). Methods We enrolled 46 patients with myofascial CPP to compare the effectiveness of a 10-session routine physiotherapy course versus a 6-session RM with an integrated device (HIGGS) in alleviating MPPS morbidity and pelvic floor muscle (PFM) rehabilitation. The primary outcome was reduction in pelvic pain after the final session and in the follow-up period 3 months after the final intervention session. Results The 6-session therapy in the RM group and the manual, biofeedback, and transcutaneous electrical nerve stimulation therapies in the physiotherapy group were similarly effective in reducing pain and improving PFM endurance after the final intervention session in each group, whereas perineometer readings and PFM strength were associated with greater improvements in the physiotherapy group. Conclusion The results of this study demonstrated comparable effectiveness of RM in the management of MPPS and improvement of PFM function compared to routine physiotherapy programs with fewer sessions of therapy.
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Effect of Foliar and Root Application of Silicon Against Rice Blast Fungus in MR219 Rice Variety
Farnaz Abed-Ashtiani,Jugah-Bin Kadir,Ahmad-Bin Selamat,Ahmad Husni Bin-Mohd Hanif,Abbas Nasehi 한국식물병리학회 2012 Plant Pathology Journal Vol.28 No.2
Rice blast disease caused by Magnaporthe grisea (Hebert)Barr [teleomorph] is one of the most devastating diseases in rice plantation areas. Silicon is considered as a useful element for a large variety of plants. Rice variety MR219 was grown in the glasshouse to investigate the function of silicon in conferring resistance against blast. Silica gel was applied to soil while sodium silicate was used as foliar spray at the rates of 0, 60, 120, 180 g/5 kg soil and 0, 1, 2, 3 ml/l respectively. The treatments were arranged in a completely randomized design. Disease severity and silicon content of leaves were compared between the non-amended controls and rice plants receiving the different rates and sources of silicon. Silicon at all rates of application significantly (α = 0.05) reduced the severity of disease with highest reduction (75%)recorded in treatments receiving 120 g of silica gel. SEM/EDX observations demonstrated a significant difference in weight concentration of silicon in silica cells on the leaf epidermis between silicon treated (25.79%) and non treated plants (7.87%) indicating that Si-fertilization resulted in higher deposition of Si in silica cells in comparison with non-treated plants. Application of silicon also led to a significant increase in Si contents of leaves. Contrast procedures indicated higher efficiency of silica gel in comparison to sodium silicate in almost all parameters assessed. The results suggest that mitigated levels of disease were associated with silicification and fortification of leaf epidermal cells through silicon fertilization.
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H. R. Rezaei Ashtiani,A. A. Shayanpoor 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12
In this investigation, processing maps and artificial neural network (ANN) models were carried out to describe and predictthe flow behavior of pure aluminum at various initial grain sizes in the hot working conditions. The elevated temperatureflow behavior of AA1070 aluminum was done through isothermal hot compressive tests in a large range of initial grain size(IGS) (50–450 μm), strain rate (0.005–0.5 s−1) and temperature (623–773 K). Consequences showed that the flow stress canbe remarkably influenced by the initial grain size at high temperatures. Based on the results, the ANN model trained witha feed-forward back-propagation learning algorithm which was prepared to describe the flow behavior of pure aluminumat the elevated temperatures. In which the initial grain size, strain, temperature and strain rate were taken as input data andtrue stress was used as target data. The results showed that the developed ANN model was a powerful method to predictthe complex non-linear of the hot flow behavior of pure aluminum. The processing map was plotted and analyzed via thedynamic material model as “stable” and “unstable” regions were determined by observing the microstructure evolution. Based on this, The optimum ranges for temperature and strain rate were 623–773 K and 0.05 s−1 respectively, for fine-grainedmicrostructure (lower than 50 μm) and were 650–720 K and 0.005–0.5 s−1 respectively, for coarse-grained microstructures(over than 50 μm).
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Zonouzi, Roseata,Ashtiani, Saeid Kazemi,Hosseinkhani, Saman,Baharvand, Hossein Korean Society for Biochemistry and Molecular Biol 2006 Journal of biochemistry and molecular biology Vol.39 No.4
Embryonic stem cells (ESCs), representing a population of undifferentiated pluripotent cells with both self-renewal and multilineage differentiation characteristics, are capable of spontaneous differentiation into cardiomyocytes. The present study sought to define the kinetic characterization of lactate dehydrogenase (LDH) and creatine kinase (CK) of ESC- and neonatal-derived cardiomyocytes. Spontaneously differentiated cardiomyocytes from embryoid bodies (EBs) derived from mouse ESC line (Royan B1) and neonatal cardiomyocytes were dispersed in a buffer solution. Enzymes were extracted by sonication and centrifugation for kinetic evaluation of LDH and CK with spectrophotometric methods. While a comparison between the kinetic properties of the LDH and CK of both groups revealed not only different Michaelis constants and optimum temperatures for LDH but also different Michaelis constants and optimum pH for CK, the pH profile of LDH and optimum temperature of CK were similar. In defining some kinetic properties of cardiac metabolic enzymes of ESC-derived cardiomyocytes, our results are expected to further facilitate the use of ESCs as an experimental model.
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Nafise Shahbazian,Farzin Zokaee Ashtiani,Babak Bonakdarpour 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.2
In this study Bacillus subtilis PTCC 1023 was used for the production of protopectinase using soybean based media. The use of isolated soybean protein (ISP) and soybean flour resulted in similar protopectinase production and growth rates. The effect of medium composition on protopectinase production was studied using central composite design (CCD) methodology. The change in the concentration of ISP (1-7%), glucose (0-10%), and phosphate (0.1-0.3 M) was found to affect the protopectinase activity (response variable) after 24 hr of cultivation. In the range studied, ISP and glucose had a negative effect on the response variable, whereas phosphate had a positive effect. A statistically significant interaction was identified between phosphate and ISP, suggesting that correct optimization of medium formulation in this case can only be obtained using factorial design of experiments. Protopectinase activity exceeding 215 U/mL was obtained in a medium containing 4% ISP, 0.3M phosphate, and no added sugar.
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