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Paulo Schiavom Duarte,Luciana Audi de Castroneves,Heitor Naoki Sado,Marcelo Tatit Sapienza,Ana Amélia Fialho de Oliveira Hoff,Carlos Alberto Buchpiguel 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.4
Herein, we report a case of a 19-year-old man with multiple endocrine neoplasia type 2B (MEN2B) and medullary thyroidcarcinoma (MTC) diagnosed when he was 12 years of age. The patient had previously undergone total thyroidectomy, cervicalradiotherapy, and chemotherapy. He progressed with known bone, pulmonary, and lymph node metastases and was scanned with18F-fluoride (18F-NaF) and 68Ga-dotatate whole-body positron emission tomography/computed tomography (PET/CT) for metastaticdisease monitoring.We found that the MTC bone metastases and soft tissue calcified metastases were better characterizedon 18F-NaF PET/CT than on 68Ga-dotatate PET/CT. This case illustrates that the 18F-NaF PET/CT could be helpful not only tothe detection of bone metastases but also to the detection of calcified soft tissue metastases in patients with MTC.