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RISS 인기검색어
- 검색키워드
- 저자 : Amit Kumar Kohli (검색결과 2 건)
- 무료
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- 유료
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Nonstationary-Epileptic-Spike Detection Algorithm in EEG Signal using SNEO
Amit Kumar Kohli,Harish Kumar Garg 대한의용생체공학회 2013 Biomedical Engineering Letters (BMEL) Vol.3 No.2
Purpose This correspondence presents the evaluation of nonstationary epileptic spike (ES) detection algorithm in the electroencephalogram (EEG) signal using the smoothed nonlinear energy operator (SNEO) based on the different time-domain window functions. However, the incorporation of adaptive threshold determination procedure enhances the performance of proposed ES detector. Methods The detection procedure exploits the fact that the presence of instantaneous ES corresponds to the high instantaneous energy content at the high frequencies. In addition to the stochastic amplitude, sign and the location of appearance of triangular spikes in the synthetic EEG signal,its base-width is also considered to be variable for the nonstationary analysis. The five pairs of EEG signals,obtained from electrodes placed on the left and right frontal cortex of male adult WAG/Rij rats, are used for the testing of proposed adaptive scheme in the real-time environment,which is a genetic animal model of human epilepsy. Results The simulation results are presented to demonstrate that the choice of window function plays a significant role in the efficient detection of ESs. The computational complexity is found to be in trade-off relationship with the detection accuracy of algorithm. Conclusions It may be inferred that the real-time EEG signals (rat data) can be processed and analyzed using the proposed adaptive scheme for the ES detection, which supersedes the conventional techniques.
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Comeback of ketamine: resurfacing facts and dispelling myths
Kumar Abhijit,Kohli Amit 대한마취통증의학회 2021 Korean Journal of Anesthesiology Vol.74 No.2
Initially known as CI-581, ketamine was first synthesized in 1962 as a replacement from phencyclidine. It has since been used as an anesthetic and analgesic. In addition, it has bronchodilating, sedative, and amnestic properties, preserving airway reflexes and sympathetic nervous system tone. Since the discovery of ketamine, it has been a major topic of discussion due to controversies regarding its usage in particular sets of patients. In the past 50 years, despite its potential benefits, it is not commonly used because of concerns of “emergence phenomenon,” its use as a substance of abuse, and its systemic side effects. Since 2012, three World Health Organization reviews on ketamine have addressed its international control.Researchers have been studying this wonder drug for a decade worldwide. Many myths of ketamine regarding emergence phenomenon and its use in traumatic brain injury and open eye injury have been disproved in recent times. It is becoming popular in pre-hospital settings, critical care, emergency medicine, low-dose acute pain services, and adjuvant in regional anesthesia techniques. This review highlights the current consensus on the various applications of ketamine in the literature.
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