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Yilmaz, Ali,Ozkul, Ayca,Shin, Dong Seong,Im, Soo-Bin,Yoon, Seok-Mann,Kim, Bum-Tae The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.58 No.6
Objective : The transradial catheterization (TRC) is becoming widespread, primarily for neurointerventions. Therefore, the evaluation of radial artery puncture in clinical practice and a better understanding of the anatomy are important to improve the safety of neuroendovascular surgery. Methods : Ten formalin-fixed adult Korean cadavers were dissected to expose radial artery (RA), brachial artery (BrA) and subclvian artery (ScA), bilaterally. Vessel lengths and diameters were meaured using a caliper and distance between the specific point of vessels and the anatomical landmarks including the radial styloid process, the medial epicondyle of the humerus, the sternoclavicular joint, and the vertebral artery orifice were also measured. Results : The average length between the radial (RAPS) and the BrA puncture sites (BrAPS) and between the vertebral artery orifice (VAO) and the BrA bifurcation (BrAB) did not differ between sides (p>0.05). The average length between the radial styloid process (RSP) and the RAPS was $13.41{\pm}2.19mm$, and the RSP was $26.85{\pm}2.47mm$ from the median nerve (MN). The mean length between the medial epicondyle (ME) and the BrAPS as $44.23{\pm}5.47mm$, whereas the distance between the ME and the MN was $42.23{\pm}4.77mm$. The average VAO-ScA angle was $70.94{\pm}6.12^{\circ}$, and the length between the ScA junction (SCJ) and the VAO was $60.30{\pm}8.48mm$. Conclusion : This study provides basic anatomical information about the radial artery and the brachial route and can help improving new techniques, selection of size and shape of catheters for TRC. This can help neurointerventionists who adopt a transradial neuroendovascular approach and offers comprehensive and safe care to their patients.
Alper Erdem Yilmaz,Baybars Ali Fil,Murat Tolga Yilmaz,Serkan Bayar,Zuhal Koksal The Korean Electrochemical Society 2024 Journal of electrochemical science and technology Vol.15 No.1
This work aims to investigate the efficiency of electrocoagulation (EC) of pistachio processing industrial wastewater (PPIW) using the continuous EC process. The tubular reactor made of stainless steel with an internal diameter of 60 mm was used as a cathode electrode. The effect of some parameters was examined on the removal of chemical oxygen demand (COD) and total phenols (TP) removal efficiency. The influences of the initial pH of wastewater (from 4 to 8), flow rate (from 25 to 125 mL/min), current density (from 7 to 21 mA/cm<sup>2</sup>), and supporting electrolyte type (NaCl, NaNO<sub>3</sub>, and Na<sub>2</sub>SO<sub>4</sub>), supporting electrolyte concentration (from 10 to 100 mg/L NaCl) on removal efficiency were investigated to determine the best experimental conditions. The examination of the physico-chemical parameters during the EC treatment showed that the best removal efficiency was obtained under conditions where the flow rate was 25 mL/min (20 min reaction time), the pH value was 5.2, and the current density was 21 mA/cm<sup>2</sup> has set. Under these experimental conditions, COD and TP removal efficiency were found to be 75% and 97%, respectively, while energy consumption was 18.5 kW h/m<sup>3</sup>. The study results show that the EC can be applied to PPIW pre-treatment.
Ali Fahir Ozer,Tunc Oktenoglu,Emrah Egemen,Mehdi Sasani,Atilla Yilmaz,Deniz Ufuk Erbulut,Onur Yaman,Tuncer Suzer 대한정형외과학회 2017 Clinics in Orthopedic Surgery Vol.9 No.3
Background: This study compares the clinical and radiological results of three most commonly used dynamic stabilization systems in the field of orthopedic surgery. Methods: A total of 71 patients underwent single-level posterior transpedicular dynamic stabilization between 2011 and 2014 due to lumbar degenerative disc disease. Three different dynamic systems used include: (1) the Dynesys system; (2) a dynamic screw with a PEEK rod; and (3) a full dynamic system (a dynamic screw with a dynamic rod; BalanC). The mean patient age was 45.8 years. The mean follow-up was 29.7 months. Clinical and radiological data were obtained for each patient preoperatively and at 6, 12, and 24 months of follow-up. Results: Clinical outcomes were significantly improved in all patients. There were no significant differences in the radiological outcomes among the groups divided according to the system used. Screw loosening was detected in 2 patients, and 1 patient developed screw breakage. All patients with screw loosening or breakage underwent revision surgery. Conclusions: Each procedure offered satisfactory outcome regardless of which system was applied.
Yilmaz, Resul,Ates, Omer,Gul, Ali,Kasap, Tuba,Ozer, Samet,Ensari, Emel The Korean Society of Pediatric Gastroenterology 2019 Pediatric gastroenterology, hepatology & nutrition Vol.22 No.5
Purpose: The ${\beta}3-adrenergic$ receptor (ADRB3) is expressed in visceral adipose tissue and has been speculated to contribute to lipolysis, energy metabolism, and regulation of the metabolic rate. In this study, we aimed to investigate the association of polymorphism of the ADRB3 gene with the sex of children with obesity and related pathologies. Methods: ADRB3 gene trp64arg genotyping was conducted in 441 children aged 6-18 years. Among these subjects, 264 were obese (103 boys; 161 girls) and 179 were of normal weight (81 boys; 98 girls). In the obese group, fasting lipids, glucose and insulin levels, and blood pressure were measured. Metabolic syndrome (MS) was defined according to the modified World Health Organization criteria adapted for children. Results: The frequency of trp64arg genotype was similar in obese and normal weight children. In obese children, serum lipid, glucose, and insulin levels; homeostasis model assessment of insulin resistance (HOMA-IR) scores; and MS were not different between arg allele carriers (trp64arg) and noncarriers (trp64trp). In 264 obese children, genetic analysis results revealed that the arg allele carriers were significantly higher in girls than in boys (p=0.001). In the normal weight group, no statistically significant difference was found between genotypes of boys and girls (p=0.771). Conclusion: Trp64arg polymorphism of the ADRB3 gene was not associated with obesity and MS in Turkish children and adolescents. Although no relationships were observed between the genotypes and lipids, glucose/insulin levels, or HOMA-IR, the presence of trp64arg variant was frequent in obese girls, which can lead to weight gain as well as difficulty in losing weight in women.
Investigation of ICAM-1 and β3 Integrin Gene Variations in Patients with Brain Tumors
Yilmaz, Umit,Zeybek, Umit,Kahraman, Ozlem Timirci,Kafadar, Ali Metin,Toptas, Bahar,Yamak, Nesibe,Celik, Faruk,Yaylim, Ilhan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10
Background: Primary brain tumors constitute a small percent of all malignant cancers, but their etiology remains poorly understood. ${\beta}3$ integrin (ITGB3) has been recognized to play influential roles in angiogenesis, tumor growth and metastasis. Intercellular adhesion molecule-1 (ICAM-1) is a surface glycoprotein important for tumor invasion and angiogenesis. The aim of this study was to investigate whether specific genetic polymorphisms of ICAM-1 and ITGB3 could be associated with brain cancer development and progression in a Turkish population. Our study is the first to our knowledge to investigate the relationship between brain tumor risk and ICAM-1 and ${\beta}3$ integrin gene polymorphisms. Materials and Methods: The study covered 92 patients with primary brain tumors and 92 age-matched healthy control subjects. Evaluation of ${\beta}3$ integrin (Leu33Pro (rs5918)) and ICAM-1 (R241G (rs1799969) and K469E (rs5498)) gene polymorphisms was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: According to results of our research, the A allele of the ICAM-1 R241G gene polymorphism appeared to be a risk factor for primary brain tumors (p<0.001). Similarly, the frequency of the A mutant allele of ICAM-1 R241G was statistically significant in patients with brain tumors classified as glioma (p<0.001). When allele and genotype distributions of ICAM-1 K469E, ICAM-1 R241G and ${\beta}3$ integrin Leu33Pro gene polymorphisms were evaluated with age, sex, and smoking, there were no statistically significant differences. Haplotype analysis revealed that the frequencies of GAC (rs1799969-rs5498-rs5918) and GAT (rs1799969-rs5498-rs5918) haplotypes were significantly lower in patients as compared with controls (p=0.001; p=0.036 respectively). Conclusions: This study provides the first evidence that ICAM-1 R241G SNP significantly contributes to the risk of primary brain tumors in a Turkish population. In addition, our results suggest that ICAM-1 R241G in combination ICAM-1 K469E may have protective effects against the development of brain cancer.
Adsorption of Ni(II) on ion exchange resin: Kinetics, equilibrium and thermodynamic studies
Baybars Ali Fil,Recep Boncukcuoglu,Alper Erdem Yilmaz,Serkan Bayar 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.9
This article describes the ion exchange of a heavy metal Ni(II) from aqueous solutions onto a Dowex HCR-S, cationic resin. Batch adsorption studies were conducted to evaluate the effect of various parameters such as pH, resin dose, stirring speed, temperature, contact time and initial Ni(II) concentration on the removal of Ni(II). Adsorption rate increased with the increase in initial nickel concentration, stirring speed and temperature. Equilibrium adsorption isotherms were measured for the single component system, and the experimental data were analyzed by using Langmuir, Freundlich, Elovich, Temkin, Khan, Sips, Toth, Koble-Corrigan and Radke-Prausnitz isotherm equations. The Sips equation appears to fit the equilibrium data. Different models were tested for their applicability. Adsorption kinetic data were modeled using the Lagergren pseudo-first-order, Ho’s pseudo-second-order and Elovich models. It was found that Ho’s pseudo-second-order model could be used for the prediction of the system’s kinetics. Thermodynamic activation parameters such as ΔG*, ΔS* and ΔH* of the adsorption of Ni(II) on Dowex HCR-S cationic resin were also calculated.
SOME PROPERTIES OF SYMMETRIC BI-(σ, Τ)-DERIVATIONS IN NEAR-RINGS
Ceven, Yilmaz,Ozturk, Mehmet Ali Korean Mathematical Society 2007 대한수학회논문집 Vol.22 No.4
In this paper, we introduce a symmetric $bi-({\sigma},\;{\tau})-derivation$ in a near-ring and generalize some of the results in [5, 6, 8, 9].
Baybars Ali, Fil,Cansu, Elgun,Sevim Alya, Cihan,Sermin, Gunaslan,Alper Erdem, Yilmaz The Korean Electrochemical Society 2022 Journal of electrochemical science and technology Vol.13 No.4
In the study, Ni<sup>2+</sup> (nickel) removal from synthetically prepared wastewater by electrocoagulation method, which is one of the electrochemical treatment processes, was investigated and parameters such as current density, pH, mixing speed, initial Ni<sup>2+</sup> concentration, supporting electrolyte type and concentration were determined to determine Ni<sup>2+</sup> removal efficiencies effects were studied. Experiment conditions during 30 minutes of electrolysis; the current density was determined as 0.95 mA/cm<sup>2</sup>, the initial pH of the wastewater was 6, the mixing speed was 150 rpm, and the initial nickel concentration was 250 mg/L. The Ni<sup>2+</sup> removal efficiency was obtained as 75.99% under the determined experimental conditions, while the energy consumption was calculated as 3.15 kW-h/m<sup>3</sup>. In the experiments, it was observed that the type and concentration of the supporting electrolyte did not have a significant effect on the Ni<sup>2+</sup> removal efficiency. In the trials where the effect of the support electrolyte concentration was examined, the Ni<sup>2+</sup> removal efficiency was 75.99% in the wastewater environment without the supporting electrolyte, while the Ni<sup>2+</sup> removal efficiency was 81.55% when 7.5 mmol/L NaCl was used after the 30-minute reaction, and the energy consumption was 2.15 kW-h/m<sup>3</sup> obtained as. As a result of the studies, it was concluded that the electrocoagulation process can be applied in the treatment of wastewater containing Ni<sup>2+</sup>.