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RISS 인기검색어
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- 저자 : Abbas Rahmani (검색결과 3 건)
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Abbas Rahmani,Abbas Ali Rostami,Mohsen Pirdashti,Poorya Mobalegholeslam 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.4
Liquid-liquid equilibrium data for poly vinyl pyrrolidone (PVP) K30+K2HPO4+H2O system were measured at 298.15 K and different pH values (7.54, 8.05, and 9.47). A binodal curve was fitted to the Merchuk equation and the tie line compositions were fitted to both the Othmer-Tobias and Bancroft equations. The refractive indices and densities of several homogeneous binary and ternary solutions used for calibration were also measured within a range of 0-30 mass% of PVP and 0-50 mass% of K2HPO4. Then, the viscosities, densities, electrical conductivities, and refractive indices of binary (PVP K30+water; potassium phosphate+water) and ternary (PVP K30+potassium phosphate+ water) systems were measured and correlated at different pH values. The density data showed a linear variation of the polymer and salt mass fractions. The viscosity data of PVP K30 solutions were correlated as a function of the mass fractions by using a nonlinear equation. The effects of the tie line lengths on the densities and viscosities of the aqueous two-phase systems were represented. Also, the modified UNIFAC-NRF is used to calculate the phase equilibria of the mention system. The fitted binary interaction parameters of the model were reported.
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Mina Rahmani,Masoumeh Fardi,Majid Farshdousti Hagh,Abbas Ali Hosseinpour Feizi,Mehdi Talebi,Saeed Solali 대한혈액학회 2019 Blood Research Vol.54 No.2
BackgroundIkaros family zinc finger 1 (IKZF1)is a transcription factor with an important role in control-ling hematopoietic proliferation and function, particularly lymphoid cell differentiation. It was previously shown that various mechanisms and expression patterns of Ikaros are linked to a variety of cancers. We hypothesized that aberrant methylation (hypomethylat-ion) of the IKZF1 promoter region might be one of the causes of B-cell acute lymphoblastic leukemia (B-ALL). In B-ALL patients, an increased expression of this gene is a potential cause of B-cell differentiation arrest and proliferation induction. Therefore, as more than 90% of patients with ALL are <15 years old, we investigated the methylation pattern of the IKZF1 promoter in childhood B-ALL.MethodsTwenty-five newly diagnosed B-ALL cases were included (all younger than 15 yr). In addi-tion, we selected 25 healthy age- and sex-matched children as the control group. We col-lected the blood samples in EDTA-containing tubes and isolated lymphocytes from whole blood using Ficoll 1.077 Lymphosep. Next, we extracted genomic DNA with the phe-nol/chloroform method. Two microgram of DNA per sample was treated with sodium bisulfite using the EpiTect Bisulfite Kit, followed by an assessment of DNA methylation by polymerase chain reaction (PCR) analysis of the bisulfite-modified genomic DNA.ResultsOur data highlighted a hypomethylated status of the IKZF1 promoter in the ALL cases (96% of the cases were unmethylated). In contrast, the control group samples were parti-ally methylated (68%).ConclusionThis study demonstrated a hypomethylated pattern of the IKZF1 promoter region in child-hood B-ALL, which might underlie the aberrant Ikaros expression patterns that were pre-viously linked to this malignancy.
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Financial Distress and its Predicting Factors among Iranian Cancer Patients
Fathollahzade, Abazar,Rahmani, Azad,Dadashzadeh, Abbas,Gahramanian, Akram,Esfahani, Ali,Javanganji, Leila,Nabiolahi, Leila Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4
Background: Financial distress due to the cost of cancer treatments is prevalent among cancer patients. Identifying the level of financial distress and its affecting factors has an important role in providing supportive services. Accordingly, the aims of this study were to determine these parameters among Iranian cancer patients. Materials and Methods: This descriptive-correlational study was undertaken among 262 cancer patients admitted to both private and public hospitals in East Azerbaijan province, Iran. The financial distress/financial well being scale was used to determine financial distress. The data were analyzed using SPSS software using descriptive and inferential statistics (multiple linear regression). Results: Among the 262 cancer patients, 57.3% were male and their mean age was 47.0 years. The mean score for financial distress was 4.12 (2.01). The final regression model demonstrated that the independent variables (predictors) of income less than living expenses, income equal to living expenses, having an employed spouse in governmental job and living with parents, with regression coefficients of -1.029, -0.515, 0.198, and 0.096, respectively, were predictors of financial distress among cancer patients. These variables accounted for 50% of changes in variance of financial distress. Conclusions: Iranian cancer patients have moderate to high levels of financial distress. Considering policies for managing direct and indirect costs of cancer treatments must be followed.
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