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      • KCI등재

        Effectiveness of Different Cleaning Agents against the Colonization of Candida spp and the in Vitro Detection of the Adherence of These Yeast Cells to Denture Acrylic Surfaces

        A. Dilek Nalbant,Ayse Kalkanci,Bano Filiz,Semra Kustimur 연세대학교의과대학 2008 Yonsei medical journal Vol.49 No.4

        Purpose: The aim of this study is to examine the effect Klorhex and Fittydent, which are used as  cleaning agents on the adhesion of Candida on the surfaces of acrylic denture and palatal mucosa. In addition, ability of yeasts to adhere to acrylic strips was evaluated after applying these agents in vitro. Materials and Methods: Each group of 15 patients  cleaned their dentures with either Klorhex or with Fittydent. The control group cleaned their dentures  with water. Results: It was found that  62.2% of  the patients had colonies of Candida species on their palatal mucosa which was reduced to 51.1%  after using these cleaning agents. The colonization rate with Candida spp on their dentures  was reduces from  82.2% to  68.8%  using these cleaning agents.  The mean adhesion value of the Candida strains isolated from the acrylic strips were found to be 75cell/strip prior to applying the Klorhex and Fittydent  and 37.5cell/strip and 15cell/strip after  applying these agents, respectively. Conclusion: These results showed that Klorhex and Fittydent have a certain preventive effect on the colonization rate of Candida spp on the surface of these dentures, the palatal mucosa, as well as on the acrylic strips in vitro.

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