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      • KCI등재

        상악동에 발생한 국균증에 관한 증례보고

        채병무(Byung Moo Chae),조현주(Hyun Joo Jo),정용선(Yong Seon Jeong),정태영(Tae Young Jung),강미선(Mi Seon Kang),박상준(Sang Jun Park) 대한구강악안면병리학회 2010 대한구강악안면병리학회지 Vol.34 No.6

        This infection includes an allergic bronchial reaction, an aspergilloma, and an invasive aspergillosis, which is more common in immunosuppressed patients and presents as multiorgan disease. The maxillary sinus is a relatively common site for formation of an aspergilloma where it forms around a nexus of foreign body. It has been indicated that the foreign body containing zinc extruded into the maxillary sinus has the potential to become infected and form an aspergilloma. The treatment of this disease is radical surgery and adjunctive systemic antifungal therapy. This is a case report of solitary aspergillosis of the right maxillary sinus. We experienced a case of right maxillary sinus aspergillosis in a 37 years old male who has dull pain on right temporal and zygoma area. We reported a case with review of literature.

      • SCIESCOPUSKCI등재

        미노클린 첨부제의 구강점막 독성 및 치은조직내에서의 생분해에 관한 연구

        병무,김형섭,한상섭,이호일,현석,Rim, Byung-Moo,Kim, Hyung-Seop,Han, Sang-Sup,Lee, Ho-Il,Chae, Hyun-Sok 대한치주과학회 1994 Journal of Periodontal & Implant Science Vol.24 No.2

        Minocline Strip(MS), a local drug delivery developed as a controlling means for microoragnisms in gingival wound and periodontitis, was implanted in the gingiva of experimental animals. The toxic effects and biodegradation of MS were studied in respect to pathological changes induced in gingival tissue. The experimental animals treated with MS had not showed significant difference in symptom, body weights, feed and water intake, and blood analysis throughout 150 days of experimental period, but revealed significantly increased values of total WBC counts and AST (SGOT) on the 7th day, compared with controls. The treated animals revealed petechial hemorrhage and severe edema accompanying degeneration and necrosis of damaged muscle fibers around the surgical wound, but no local inflammatory reaction and concerned lesions were found. The implanted MS became encapsulated by thin connective tissue, and its size and color diminished gradually according to the experimental term. The MS-like material appeared in the nearby lymphatics on the 110th day. The implated MS remained as fine granular particles or disappeared on the 130th day, and the decrease of its volume and density were variable depending on each individual. These results indicate that long-term implantation of MS may not produce inflammation or toxic effects, and eventually lead to complete biodegradation.

      • SCOPUSKCI등재

        Morphological changes of Schwann cells as neurotoxic responses

        병무,현석,이오형,Rim, Byung-moo,Chae, Hyun-sok,Lee, Oh-hyung The Korean Society of Veterinary Science 1994 大韓獸醫學會誌 Vol.34 No.4

        본 실험에서 초산납 투여로 인한 실험초기에 관찰할 수 있는 신경독성은 Schwann 세포의 종창이었다. 종창의 정도를 계측하기 위해 각 실험군 rat의 좌골신경을 횡단 조직표본으로 제작하여 Schwann세포의 두께와 핵의 장경을 측정 비교하였다. 즉 제1실험군은 30일간 0.5% 초산납이 함유된 음료수를 공급하였고 제2실험군은 제1군과 동일한 처리후 일반 실험실 조건에서 30일간 회복되게 하였으며 제3군은 대조군으로 정상 사육하였다. 초산납을 투여한 제1실험에서는 Schwann세포의 두께가 대조군보다 유의한 증가치를 보였는데, 제2실험군은 대조군과 유의한 차이가 없었다. Schwann세포핵의 직경 역시 제1군이 대조군보다 증가되었으나 유의한 차이는 없었다. The early change observed in lead-induced neurophathy in the rat was Schwann cell swelling. In order to quantify this cell swelling, Schwann cell thickness and major diameter of the nucleus were measured using tranverse section with associated myelinated fiber of sciatic nerves. Group I rats were intoxicated with 0.5% lead acetate in the drinking water for 30 days; group II animals were treated as in group I and then restored to normal laboratory conditions for 30 days; and group III were controls. The results showed that the cell sizes were significantly greater in intoxicated animals, compared with control, and the cell sizes of group II did not differ significantly from control rats.

      • KCI등재

        치성감염에 의한 하행 괴사성 종격동염: 증례보고

        정용선,채병무,조현주,김소현,정태영,박상준,Jeong, Yong-Seon,Chae, Byung-Moo,Jo, Hyun-Joo,Kim, So-Hyun,Jung, Tae-Young,Park, Sang-Jun 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.6

        Descending necrotizing mediastinitis (DNM) is a complication of odontogenic or oropharyngeal infections that can spread to the mediastinum. Such infections is serious, leading to sepsis and frequently to death. Even in this era of antibiotics, the mortality rate associated with DNM is approximately 40%. It is difficult to diagnose early because clinical and radiologic findings appear in the late stage of the infection. Delayed diagnosis is the principal reason for the high mortality in DNM. Therefore, descending necrotizing mediastinitis requires an early and aggressive surgical approach to reduce the high morbidity and mortality associated with this disease. We experienced a case of odontogenic infection followed by acute mediastinitis, so present now with the review of literatures.

      • KCI등재

        급성 치성상악동염으로 인한 안구후농양: 증례보고

        조현주,정용선,채병무,정태영,박상준,Jo, Hyun-Joo,Jeong, Yong-Seon,Chae, Byung-Moo,Jung, Tae-Young,Park, Sang-Jun 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.6

        Retrobulbar abscess is a rare, but severe complication of paranasal sinusitis. The clinical presentations are eyelid swelling, erythema, proptosis, conjunctival chemosis, restricted ocular movement, and decreased visual acuity. Diagnostic methods available for evaluating retrobulbar abscess include sinus X-ray, ultrasonography, computed tomography (CT), and bacterial culture. For the treatment of retrobulbar abscess, immediate surgical drainage and systemic antibiotic therapy are needed. Proper diagnosis and treatments are necessary for preventing visual loss, cavernous sinus thrombosis, subdural abscess, and other lifethreatening complications. A patient, a 30-year-old man, was admitted to our hospital because of progressive eyelid swelling, erythema, ptosis and decreased visual acuity on the right eye after endodontic treatment. The sinusitis occurred secondary to the infection from an upper molar tooth. The spread of the infection led to the orbit via ethmoidal sinus and posterior orbital wall. Immediate surgical intervention was performed and systemic antibiotics was administrated. The symptoms and signs are improved after treatments, so we present our case with a brief review of the literature.

      • KCI등재

        치성감염의 확산으로 인한 후인두간극농양:

        정태영(Tae-Young Jung),채병무(Byung-Moo Chae),정용선(Yong-Seon Jeong),박상준(Sang-Jun Park) 대한구강악안면외과학회 2010 대한구강악안면외과학회지 Vol.36 No.4

        Odontogenic infections are a normally locally confined, self-limiting process that is easily treated by antibiotic therapy and local surgical treatment. However, it may spread into the surrounding tissues through a perforation of the bone, and into contiguous fascial spaces or planes like the primary or secondary fascial spaces. If the infection extends widely, it may spread into the lateral pharyngeal and retropharyngeal space. The retropharyngeal space is located posterior to the pharynx. If an odontogenic infection spreads into this space, severe life-threatening complications will occur, such as airway obstruction, mediastinitis, pericarditis, pleurisy, pulmonary abscess, aspiration pneumonia and hematogenous dissemination to the distant organs. The mortality rate of mediastinitis ranges from 35% to 50%. Therefore, a rapid evaluation and treatment are essential for treating retropharyngeal space abscesses and preventing severe complications. Recently, we encountered two cases of a retropharyngeal space abscess due to the spread of an odontogenic infection. In all patients, early diagnosis was performed by computed tomography scanning and a physical examination. All patients were treated successfully by extensive surgical and antibiotic therapy.

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