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      • KCI등재

        출혈성 쇼크와 패혈성 쇼크에서 쇼크인덱스의 의의

        이베안 ( Be Ahn Lee ),정상헌 ( Sang Hun Jung ),한갑수 ( Gap Su Han ),이성우 ( Sung Woo Lee ),홍윤식 ( Yun Sik Hong ) 대한외상학회 2004 大韓外傷學會誌 Vol.17 No.1

        Background: Shock Index (SI) is a ratio calculated to weigh Heart rate and Systolic Blood Pressure (SBP) differently. As we know increased the SI over 0.9 is a early predictor of circulatory failure induced by hypovolemia. This study was designed to evaluate the SI as a value of prognostic factor in Hemmorrhagic Shock and Septic Shock patients. Methods: From March 2001 to February 2002, patients presenting to the Emergency department with post traumatic hemorrhagic shock and septic shock patients. Exclusion criteria were age less than 15 years, cardiopulmonary arrest and death on arrival. We compared with admission days, ICU periods, survival rate, Revised trauma score, Base excess, and total amounts of transfusion for evaluation of reliability. Two groups were identified by the SI: group1 had an SI of more than 0.9, and group2 had an SI of less than 0.9. Results: There were 29 hemmorrhagic shock patients, and 30 septic shock patiens. In hemorrhagic shock, group 1 had significantly higher value of compared items (p<0.05). In septic shock, the value were not significantly different between group1 and group 2 (p> 0.05). Conclusion: The SI may be useful to evaluate acute hemodynamic status induced by hypovolemia. But the SI cannot be useful to evaluate hemodynamic status induced by multiorgan dysfunction. The SI cannot be a predictor of prognosis in septic shock.

      • KCI등재

        호중구 세포에 대한 고장액의 영향에 대한 연구

        정인철 ( In Chul Jung ),이베안 ( Be Ahn Lee ),김낙훈 ( Nak Hoon Kim ),박종수 ( Jong Soo Park ),최성혁 ( Sung Hyuk Choi ),홍윤식 ( Yun Sik Hong ) 대한외상학회 2004 大韓外傷學會誌 Vol.17 No.2

        Background: To investigate the effects of hypertonic saline on the generation of oxygenderived free radicals in neutrophils, this study was designed. Methods: Human PMNs were isolated from healthy volunteers` peripheral blood by the modified Boyum method. Human PMNs were incubated in 140 mM, 180 mM, 200 mM NaCl with or without fMLP, and then the production of H2O2 was measured with a flow cytometer at 5, 30, 60, 120, and 180 minutes. Isolated PMNs were incubated in 180 mM NaCl before fMLP, after fMLP and also at the same time. H2O2 production was measured by flow cytometry. Results: Hypertonic saline resulted in the suppression of fMLP-mediated H2O2 production in human PMNs. There was no statistical difference in H2O2 production according to the NaCl concentration between 180 mM and 200 mM. fMLP-mediated H2O2 production in human PMNs did not decreased at hypertonic saline infusion after fMLP. Administration of hypertonic saline decrease fMLP-mediated H2O2 production in human PMNs and concentration of 180 mM Na+is effective as well as 200 mM Na+. However, the effects of hypertonic saline is minimal when hypertonic saline was administration after PMNs were stimulated. Conclusions: It is considered that early resuscitation is required in clinically.

      • 상지의 운동제한을 보이는 소아에서 방사선 검사의 필요성

        이성우,문성우,윤영훈,이베안,정상헌,전정민,홍윤식 대한응급의학회 2002 대한응급의학회지 Vol.13 No.3

        Purpose: The study was designed to identify the necessity of radiographs and to decrease overutilization of radiographs in uncommunicable children who do not move their arms. This study provides clinical guidelines on radiographic evaluation and treatment of children with limited motion in the upper extremity. Methods: The cases of one hundred thirteen pediatric patients under 36 months of age, who had visited the Emergency Center of Korea University Ansan Hospital from January 2000 to December 2001, were retrospectively reviewed. Pediatric patients with upper extremity injuries due to multiple trauma, laceration or motor vehicle accident were excluded. Parameters analyzed were age, sex, mechanism of injury, physical findings, radiographic finding, and injuried upper extremity region. We described focal tenderness and regional edema as physical finding. Each patient without regional edema was classified into an improved or a not-improved group depending on the outcomes after manual reduction. All statistical tests were conducted with two-tailed levels of 0.05. Results: Of the 113 patients, the mean age was 18.6±0.89 months. The most common injury mechanisms were unknown and traction. Minimal edema in the elbow joint was seen in 5 cases, and supracondylar fractures due to short falls were seen in 4 (80%) of those cases (p<0.05). The improved group was finally confined to radial head subluxation in 88 patients. Although all the not-improved-group patients had received radiographs, no abnormal findings were seen in the elbow. However, clavicle fracture due to fall above or from a level surface were seen in 4 cases (20%) of the not-improved group (p<0.05). No difference of injury mechanism existed between the improved and the not-improved groups. Conclusion: Recommand Radiographic evaluations in Children not-used arm with regional edema before manual reduction. But without regional edema, manual reduction of elbow is first. If children without regional edema do not improve after manual reduction of elbow and they are injuried due to fall, children should be assessed for fractures of clavicle.

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