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심재광 ( Jae-kwang Shim ),김광철 ( Gwang-chul Kim ) 한국목재공학회 2017 목재공학 Vol.45 No.5
목조건축의 기반을 넓히고 소비자의 만족도를 향상시키기 위해 기존의 일반목조벽체 및 기타 경량목조벽체에 대한 비교 연구가 필요하다. 따라서 본 연구에서는 일반벽체와 개선된 방식인 교호 샛기둥 벽체와의 성능 비교를 통해 새로운 가능성을 찾고자 하였다. 우선 교호 샛기둥 벽체의 강도적 특성을 평가하고 일반벽체의 강도적 특성을 비교하였다. 일반벽체를 구성하는 목재의 단면이 교호 샛기둥 벽체보다 크기 때문에 일반벽체의 최대하중이 교호 샛기둥 벽체 보다 크게 나타났다. 하지만, 두 그룹간의 통계분석에 의하면 95% 신뢰 수준에서 유의성을 보이지 않아, 교호 샛기둥 벽체는 일반벽체를 대체할 수 있는 가능성을 보여주었다. 교호 샛기둥 벽채는 샛기둥의 단면이 일반벽체보다 작기 때문에 재료를 절약할 수 있어서 일반벽체보다 더 경제적이라고 판단된다. 또한 단열재의 면적 또한 증가하므로 열교 현상의 개선도 기대된다. A comparative research on the traditional standard wood walls and other light-frame wood walls is necessary to expand the base of wooden buildings and improve consumer satisfaction. Therefore, in this research we looked for new possibilities through comparison of performance between standard wood wall and newly presented staggered stud wood wall. First, the strength characteristics of staggered stud wood walls were evaluated and the those of standard wood walls were compared. The ultimate load of the standard wall was larger than that of the staggered stud wood wall, because the cross section of the wood making up the standard wood wall was larger than that of the staggered stud wood wall. However, the statistical analysis between the two groups didn`t showed a significance of 95% confidence level. This means that, staggered stud wood walls have shown the possibility of replacing the standard wood wall. Because the cross-section of the stud in the staggered stud wood walls is smaller than that of the standard wall, the material can be saved. Therefore, staggerd wood stud wall is judged to be more economical than the standard wall. In addition, since the area of the insulation also increases, improvement of the heat bridge is also expected.
한국의 한 대학병원에서 수집된 Acinetobacter baumannii 임상분리주의 meropenem 내성에 대한 AdeABC 유출펌프의 역할
심재광(Jae-Kwang Shim),최지애(Ji Ae Choi),김춘미(Choon-Mee Kim),고영진(Young Jin Ko),강성호(Seong-Ho Kang),박건(Geon Park),장숙진(Sook Jin Jang) 조선대학교 의학연구원 2020 The Medical Journal of Chosun University Vol.45 No.2
The aim of this study is to investigate the role of the AdeABC efflux pump to meropenem resistance in 116 clinical isolates of Acinetobacter baumannii collected from a university hospital in Korea. We performed real-time RT-PCR to test the relative expression of adeB efflux pumps gene in them. The ratio of meropenem MIC change due to carbonyl cyanide m-chlorophenylhydrazone (CCCP), efflux pump inhibitor, was calculated. It was judged that the efflux pump contributed to meropenem resistance when the changed ratio of meropenem MIC by CCCP was 4 or more. The mean and standard error of the adeB relative expression level in the susceptible and resistant groups to meropenem were 3.2±0.8 and 11.9±2.9, respectively and there was a significant difference between the two groups (p<0.0001). The ratio of meropenem MIC changes due to CCCP to 4 or higher in the susceptible and resistant groups to meropenem were 17.4% and 20.4%, respectively, and there was no significant difference between them. No correlation was observed between the adeB expression and the ratio of meropenem MIC change due to CCCP. It is considered that the adeB efflux pump did not significantly affect meropenem resistance in most strains of A. baumannii tested in this study.
이동진,심재광,안승헌,Lee, Dong-Jin,Shim, Jae-Kwang,An, Seung-Heon 대한물리치료학회 2011 대한물리치료학회지 Vol.23 No.2
Purpose: The aim of this study was to investigate the prevalence of depressive symptoms in stroke patients and to compare characteristics of different rating scales - Hamilton Depression Rating Scale (HDRS), Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale-Depression (HAD.D)- with regard to diagnosis and severity assessment for post-stroke depression. Methods: Participants included 44 stroke patients who could communicate. At admission, all study participants received a semi-structured interview using the HDRS and a self-completed questionnaire using the BDI and the HAD-D. Pearson's correlation method was used to examine associations among the three depression scales. The BDI and HAD-D were compared based on HDRS criteria, and the sensitivity and specificity using cut-off values were analyzed. Results: The HDRS showed that 52.30% of stroke patients had depressive symptoms on the BDI and HAD-D it was 59.10%. The HDRS correlated significantly with the BDI (r=0.81, p<0.01) and HAD-D (r=0.55, p<0.01). The BDI correlated significantly with HADS (r=0.50, p<0.01). After calculating the area under the ROC curve to decide on HDRS criteria, the BDI (AUC=0.91, 95% CI: 0.83.0.99) showed a significantly larger area compared to the HAD.D (AUC=0.82, 95% CI: 0.69-0.94). The cut-off value of the BDI was 12.50 points with a sensitivity of 81.00% and a specificity of 76.20%. Conclusion: These findings show that the BDI is a useful screening test for depression that most closely predicts the HRDS score.
임상연구 : 성상신경절 차단이 돌발성 난청의 치료에 미치는 영향
송종욱 ( Jong Wook Song ),심재광 ( Jae Kwang Shim ),문진천 ( Jin Cheon Moon ),안은경 ( Eun Kyoung Ahn ),금창만 ( Chang Man Kum ),윤덕미 ( Duck Mi Yoon ),이원상 ( Won Sang Lee ),신증수 ( Cheung Soo Shin ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.1
Background: Idiopathic sudden sensorineural hearing loss (ISSNHL) is defined as a sensorineural hearing loss which develops abruptly without definitive causes. Stellate ganglion block (SGB) has been used as one of the treatment modalities in ISSNHL. However, published data establishing the effect of SGB has been slim. We conducted this study to evaluate the effect of SGB according to the factors that may influence the prognosis of the disease. Methods: We reviewed the records of 343 patients. The control group was managed with medications, and the SGB group was managed with SGB and the same medications. SGB was performed with 5 ml of 1.0% mepivacaine. The pure-tone audiogram was performed after the therapy and Siegel`s criteria was used to define the recovery of hearing. Results: The recovery rate of the SGB group was higher than that of the control group (58.1% vs. 42.1%, P < 0.05). The SGB group had a higher recovery rate than the control group in patients treated within 7 days from the onset of symptoms (66.9% vs. 44.1%, P < 0.05), without diabetes mellitus (58.5% vs. 44.9%, P < 0.05), without dizziness (61.6% vs. 44.6%, P < 0.05), or whose initial hearing loss was between 71 and 90 dB (69.4% vs. 38.9%, P < 0.05). Conclusions: SGB is thought to be a useful therapy for ISSNHL, especially in the patients treated within 7 days, without diabetes mellitus, dizziness, or whose initial hearing loss was severe. (Korean J Anesthesiol 2006; 51: 52~7)