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김세훈 ( Sae Hoon Kim ),김정은 ( Jeong Eun Kim ),정재우 ( Jae Woo Jung ),김주희 ( Joo Hee Kim ),이소희 ( So Hee Lee ),오미정 ( Mi Jung Oh ),예영민 ( Young Min Ye ),박창한 ( Chang Han Park ),강혜련 ( Hye Ryun Kang ),김태범 ( Tae Bu 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.4
Background: Although allergic and hypersensitive reactions to drugs are important clinical problems, the diagnosis of these conditions has been subject to major limitations in actual practice. This study investigated the current status of diagnostic approaches to drug allergies and the current barriers to the implementation of drug allergy testing in Korea. Methods: The drug allergy workgroup of the Korean Academy of Asthma, Allergy and Clinical Immunology sent an online questionnaire to its members. A total of 175 members voluntarily replied. The questionnaire consisted of 33 questions about the current status of test implementation and the details of testing for antibiotics, aspirin/non-steroid anti-inflammatory drugs (NSAIDs), and radiocontrast media. Results: Most subjects (97.7%) believed that drug allergy testing was necessary, but only 56.6% performed these tests in their practice. The leading barriers to drug allergy testing were lack of personnel, facilities, and/or relevant skills. Only 45.7% and 39.4% of subjects performed tests to confirm and identify the causative drug in patients suspected of allergies to antibiotics and aspirin/NSAIDs, respectively. Marked heterogeneity among the responders regarding diagnostic approach, methods of skin testing, and provocation tests for antibiotics, aspirin/NSAIDs, and radiocontrast media were found. Conclusion: Efforts to develop tests with greater clinical value and more rigorous standardization protocols are needed to improve the implementation of drug allergy testing. (Korean J Asthma Allergy Clin Immunol 2011;31:260-271)
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