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李枝映,柳深今,朴炳烈 圓光大學校 韓醫學硏究所 1993 원광한의학 Vol.3 No.1
The study has been carried out to investigate the pharmacological effects of Sibyukmiryugieum(十六味流氣飮) extract on analgesia, anti-inflammation, muscle relaxation, anti-convulsion, intestinal movement, blood pressure and uretus muscle through experimental animals. The results can be summarized as follows: 1. In the experiment of analgesic effect, the writhing syndrome induced by acetic acid was reduced by administration of Sibyukmiryugieum extract(SRE) 2. Anti-inflammatory effects which had been caused by the acetic acid injection were increased by administration of SRE. 3. In the experiment of Rota-Rod method, SRE did not affect the muscle relaxation effects of the mouse. 4. Anticonvulsion effect against the convulsion of the mouse induced by Strychnine and Picrotoxin was significantly recognized. 5. Effect of SRE on the contractile force of isolated rat ileum was recognized. Isolated rat ileum was supressed by Atropine treatment but wa snot supressed by Cyproheptadine. 6. The blood pressure was decreased by SRE. The hypotensive effect of SRE was affected by atropine pretreatment, but was not affected by cyprohiptadine(on histamine receptor). 7. The contractile force of the isolated rat uterus is increased in propotion to the amount adminstered SRE. The contractile force of the isolated rat uterus was suppressed by atropine treatment.