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홍석기(Seog Ki Hong),남재우(Jae Woo Nam),이경태(Kyung Tae Lee),신관석(Kwan Seog Sin) 대한약학회 1993 약학회지 Vol.37 No.2
6beta-(trans-3-Aryl-5-oxo-pyrrolidin-2-yl)acetamidopenicillanic acid(7a~7c) and 7beta-(trans-3-Aryl-5-oxo-pyrrolidin-2-yl)acetamidocephalosporanic acid(8a~8c) were synthesized and tested in vitro antibacterial activity. Of these new penicillins exhibited good antibacterial activity against Gram-positive bacteria whereas none of the compounds possessed the activity against Gram-negative bacteria at the concentration tested.