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- 저자 : 허병익 ( Byeong Ik Hur ) (검색결과 1 건)
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김호상 ( Ho Sang Kim ),조원호 ( Won Ho Cho ),허병익 ( Byeong Ik Hur ),강동완 ( Dong Wan Kang ),차승헌 ( Seung Heon Cha ),최창화 ( Chang Hwa Choi ) 대한뇌종양학회 2009 대한뇌종양학회지 Vol.8 No.2
Objective:Intracranial hemangioblastomas are benign vascular tumors arising either sporadically or as a manifestation of von Hippel-Lindau(VHL) disease. We analysed a series of patients with intracranial hemangioblastoma to review our strategy of treatment. Materials and Methods:Consecutive patients with intracranial hemangioblastoma who underwent surgery and then adjuvant therapy if needs, at our institute. Eighteen patients(14 female and 4 male patients) underwent 21 operations for removal of 19 intracranial hemangioblastoma(age at surgery 45±9.2 years, follow-up duration 37±8 months). Serial clinical examinations, imaging studies, and operative records were analyzed. Results:Twelve patients(66%) had sporadic hemangioblastomas. And six patients(34%) were von Hippel-Lindau disease. Symptoms and signs included headache(64.7%), dizziness(64.7%), gait disturbance(20%), and hydrocephalus(56%). Total resection rate was 71%(15/21). Six patients whose tumor were partially removed. Adjuvant radiosurgery was performed to 6 patients. Four patients of them were stabilized after radiosurgery. Two cystic hemangioblastoma cases were aggravated in the size of cystic portion, so revision were performed. Preoperative tumor embolization was performed in 2 cases. One VHL patient was expired due to pheochromocytoma. Conclusion:Symptoms and signs caused by intracranial hemangioblastoma can be treated safely and effectively with surgical resection. Radiosurgery may be adequate adjuvant therapy for remnant intracranial hemangioblastoma except cystic hemangioblastomas.
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