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증례보고 : 특발성 과호산구 증후군 환자의 마취경험 -증례보고-
조혜란 ( Hye Ran Cho ),한상지 ( Sang Ji Han ),권영은 ( Young Eun Kwon ),이준학 ( Jun Hak Lee ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.52 No.6
Idiopathic hypereosinophilic syndrome is characterized by prolonged markedly elevated peripheral blood eosinophil count and eosinophil-related tissue damage to variable organs without an identifiable underlying cause. Eosinophilopoiesis is related with T-lymphocyte activation and cytokine cascade controlling eosinophilic production. It shows tissue infiltration in many organs including endomyocardium, lung, liver, gastrointestinal tract. Here we report a case of idiopathic hypereosinophilic syndrome presenting ruptured rectus sheath hematoma due to coagulopathy involving the liver. Severe postoperative complications were developed after general anesthesia. The patient suffered from life-threatening acute respiratory distress syndrome (ARDS). This case suggest that, in patients with marked eosinophilia requiring general anesthesia, perioperative steroid cover is advisable. This may reduce or prevent serious lung damage and other complications. (Korean J Anesthesiol 2007; 52: 728~32)