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최승재 ( Sung Jay Choe ),이솔암 ( Solam Lee ),최재웅 ( Jaewoong Choi ),이원수 ( Won-soo Lee ) 대한피부과학회 2017 대한피부과학회지 Vol.55 No.7
Vulvar vestibular papillomatosis (VVP) is a benign condition that can be viewed as the female equivalent of male pearly penile papules. Clinically, VVP is quite often misdiagnosed as condyloma acuminatum. As opposed to condyloma, VVP lesions arise from a distinct mucosal base, match the color of the surrounding mucosa, show symmetrical distribution, and are limited to the inner aspect of the labia minora. Although VVP is quite well known in the gynecological field, this disease entity is not commonly recognized in dermatology settings. Furthermore, a literature search for VVP revealed only nine reports in dermatological journals including one report from Korea. Therefore, through our report we wish to create awareness among dermatologists regarding the occurrence of this frequent but often ignored entity. Recognizing and understanding that papillomatosis of the vulvar vestibule is a normal variant will help dermatologists to avoid incorrect diagnosis and repeated unnecessary treatment. (Korean J Dermatol 2017;55(7):435∼439)
흡입 수포의 체액과 혈청에서 측정한 지질들의 상관성 분석
권일주 ( Il Joo Kwon ),최승재 ( Sung Jay Choe ),정승원 ( Seung Won Jeong ),전명수 ( Myungsoo Jun ),최응호 ( Eung Ho Choi ) 대한피부과학회 2022 대한피부과학회지 Vol.60 No.3
Background: Several biomarkers are measured in the interstitial fluid (IF) obtained from suction blisters that are used by dermatologists. As abnormal lipid levels can cause health problems, several studies have investigated the composition and distribution of lipids and lipoproteins in IF. However, to date, no study has focused on examining lipid profiles in the postprandial state. Objective: This study aimed to compare postprandial changes in serum lipid profiles and IF obtained from suction blisters and investigated their correlation. Methods: Fasting and postprandial levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides were measured in paired serum samples. IF was obtained from suction blisters from 20 healthy men using enzymatic-colorimetric methods. Results: The IF/serum ratios of TC, HDL-C, and LDL-C remained unchanged postoperatively. Postprandial levels of HDL-C and LDL-C decreased in the serum but not in IF. In both fasting and postprandial states, TC, HDL-C, and LDL-C levels in the serum were positively correlated with those in the IF. Conclusion: The results of this study showed that lipoprotein cholesterol levels measured from suction blister fluids could be used as a biomarker to predict their serum levels regardless of food intake. Therefore, suction blister fluid sampling can be considered as a method to monitor serum lipid concentrations. (Korean J Dermatol 2022;60(3):159∼166)