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      • KCI등재

        두경부에 발생한 피부종양의 임상적 연구

        채진경 ( Jin Kyung Chae ),김은정 ( Eun Jung Kim ) 대한피부과학회 2016 大韓皮膚科學會誌 Vol.54 No.7

        Background: There have been many changes to the social and medical environment in Korea and many studies showed a steady increase of cutaneous tumors. But none of them included a data occurring from head and neck. Objective: To investigate the incidence and distribution of the cutaneous tumors of the head and neck. Methods: A total of 1,415 cases of head and neck cutaneous tumors were obtained from pathology specimen at Department of Dermatology between 2010 and 2014. Results: Among 1,415 cases of head and neck cutaneous tumors, 871 cases (61.5%) were benign tumors, 271 cases (19.2%) were malignant tumors, and 273 cases (19.2%) were premalignant lesions. The most common benign head and neck cutaneous tumors was epidermal cyst with 188 cases (21.6%), followed by 173 cases (19.9%) of seborrheic keratosis, 71 cases (8.2%) of intradermal nevi. Among the 271 cases of malignant head and neck cutaneous tumors, there were 164 cases (60.5%) of basal cell carcinoma, 89 cases (32.8%) of squamous cell carcinoma, 5 cases (1.8%) of malignant melanoma. The predilection sites of malignant head and neck tumors were face (87.5%), ear (4.8%) and neck (4.0%). Of the premalignant lesions, there were 210 cases (76.9%) of actinic keratosis, 36 cases (13.2%) of Bowen’s disease and 27 cases (9.9%) of actinic cheilitis. Conclusion: In our study, the proportion of malignant tumors and premalignant lesion in head and neck tumors was higher than previous reports. Also, the percentage of woman in malignant tumors and premalignant lesions was higher than man, unlike previous studies. However, these results had limitation associated with retrospective study in a single institution, and further prospective study with multi-center is required for confirmation. (Korean J Dermatol 2016;54(7):516∼524)

      • SCOPUSKCI등재

        Terbinafine에 의해 발생한 급성 전신 발진성 고름물집증

        박상현 ( Sang Hyun Park ),채진경 ( Jin Kyung Chae ),권선용 ( Sun Yong Kwon ),박건 ( Kun Park ),박석돈 ( Seok Don Park ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.2

        A 12-year-old girl visited our clinic with pruritic non-follicular pustules on reddish bases and scales on her face, trunk, and proximal extremities. She complained of fever and chills. Before she was admitted to our clinic, she had been treated with terbinafine (125 mg/day) for tinea corporis. Three days after beginning the terbinafine treatment, whitish pustules on erythematous bases occurred abruptly in the intertriginous areas. A physical examination showed that the girl’s body temperature was 38oC. Laboratory investigations revealed neutrophil-dominant leukocytosis. A skin biopsy specimen taken from a pustular lesion on the trunk revealed subcorneal pustules. The papillary dermis was edematous, and a superficial perivascular lymphocytic infiltrate with scattered interstitial neutrophils was noted. She was diagnosed as having acute generalized exanthematous pustulosis because of terbinafine use on the basis of her history, and clinical and histopathological findings. Her terbinafine treatment was discontinued promptly, and systemic corticosteroids and antihistamines were administered and topical corticosteroids were applied. Three days later, the skin lesions and constitutional symptoms had improved and there has been no recurrence to date. (Korean J Dermatol 2015;53(2):152∼156)

      • SCOPUSKCI등재

        두피의 피지모반에서 발생한 편평세포암

        권선용 ( Sun Yong Kwon ),채진경 ( Jin Kyung Chae ),박상현 ( Sang Hyun Park ),박석돈 ( Seok Don Park ),박건 ( Kun Park ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.3

        Nevus sebaceus is frequently complicated by development of a variety of other benign skin tumors. On the other hand, malignant skin tumors are rarely observed in associated with nevus sebaceous. The most common benign skin tumor developing in nevus sebaceus is trichoblastoma, while the most common malignant skin tumor is basal cell carcinoma. However, cases of squamous cell carcinoma developing within nevus sebaceous are rare. A 42-year-old man presented a solitary 3×3-cm sized hemorrhagic, crusted, verrucous mass on the left occipital scalp, which was congenital. He visited our clinic due to the mass rapidly enlarging over the past 3 years and due to bleeding of the mass in the past 3 months. Histopathologically, the tumor showed typical findings of well-differentiated nevus sebaceus and squamous cell carcinoma. We herein report a case of squamous cell carcinoma developing in nevus sebaceous. (Korean J Dermatol 2014; 52(3):182∼185)

      • SCOPUSKCI등재

        편평세포암과 상피모양육종으로 구성된 원발성 피부 암육종

        노수현 ( Soo Hyeon Noh ),채진경 ( Jin Kyung Chae ),박상현 ( Sang Hyun Park ),김은정 ( Eun Jung Kim ),박건 ( Kun Park ) 대한피부과학회 2016 대한피부과학회지 Vol.54 No.2

        Cutaneous carcinosarcoma is a biphasic, rare tumor composed of malignant epithelial and mesenchymal components. The most common carcinoma component is a squamous cell carcinoma and the most common sarcoma component is an osteosarcoma. A 74-year-old female patient presented to our hospital with a 3.5×3.5 cm-sized exophytic, eroded tumor surrounded by an erythematous plaque on her right flank that had been present for 10 years. On the incisional biopsy specimen, the tumor was composed of atypical malignant squamous cells and epithelioid cells. Furthermore, immunohistochemistry revealed that the tumor cells were positive to cytokeratin AE1/AE3, cytokeratin 5/6, epithelial membrane antigen, p63, and vimentin but were negative to HMB45, S-100, CD31, CD34, factor VIII, smooth muscle actin, and desmin. Finally, based on these histopathological and immunohistochemical findings, we diagnosed this tumor as cutaneous carcinosarcoma consisting of squamous cell carcinoma and epithelioid sarcoma. (Korean J Dermatol 2016;54(2):145∼148)

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