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- 저자 : 주영훈(Young-Hoon Joo)유이령(Ie-Ryung Yoo) (검색결과 3 건)
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후두 편평상피암종의 림프절 피막외 침범에 대한 FDG PET/CT 영상의 유용성
주영훈(Young-Hoon Joo)유이령(Ie-Ryung Yoo),조광재(Kwang-Jae Cho),송지남(Jee-Nam Song),유동준(Dong-Joon Yoo),이호석(Ho-Suk Lee),김민식(Min-Sik Kim) 대한두경부종양학회 2012 대한두경부 종양학회지 Vol.28 No.2
Backgrounds:To evaluated the use of FDG PET/CT for the identification of extracapsular spread(ECS) with histologic correlation in laryngeal cancer. Methods:We reviewed 79 medical records of patients who under-went of FDG PET/CT for laryngeal cancer before surgery. Results:ECS was present in 41.9%(18/43) dis-sected necks and in 34.5%(20/58) dissected cervical levels. There was a significant difference in the SUVmax between cervical lymph nodes with ECS and without ECS(6.39±4.53 vs. 1.19±1.64, p<0.001). The cut-off value for the SUVmax for differentiating with ECS from without ECS was 2.8 with the sensitivity of 85.7% and the specificity of 85.6%. Conclusion:The median SUVmax cut-off values of FDG PET/CT higher than 2.8 was associated with greater risk cervical lymph node metastasis with ECS in patients with laryngeal cancer.
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갑상선유두암종의 림프절 전이에 대한 FDG PET/CT 영상의 유용성
주영훈 ( Young-hoon Joo ),윤창현 ( Chang-hyun Yun ),조정해 ( Jung-hae Cho ),선동일 ( Dong-il Sun ),유이령 ( Ie-ryung Yoo ),정소령 ( So-ryoung Jung ),김민식 ( Min-sik Kim ) 대한갑상선학회 2008 International Journal of Thyroidology Vol.1 No.2
Background and Objectives: Accurate evaluation of cervical lymph node status of apillary thyroid cancer (PTC) is important to treatment planning and prognosis prediction. In this study, we evaluated the use of FDG PET/CT, ultrasound, CT or MRI (CT/MRI) for the identification of cervical nodal metastasis of PTC with histologic correlation. Materials and Methods: We reviewed 28 medical records, from 2004 August to 2007 September, of patients who underwent of FDG PET/CT, ultrasound, CT/MRI for PTC before surgery. We interpreted FDG PET/CT, ultrasound, CT/MRI to assess the regional lymph node status. We recorded lymph node metastasis according to the neck level system of imaging-based nodal classification. Results: All patients received neck dissection and 11 patients did bilateral neck dissections. Thirteen patients received total thyroidectomy and 15 patients did completion thyroidectomy. Histopathology revealed metastases in 33 of 39 (28 plus 11) dissected neck sides and in 80 of 164 dissected cervical levels. FDG PET/CT was more sensitive than CT/MRI for identification of cervical metastases on level-by-level bases (51/80 vs. 41/80; p=0.002). But the sensitivity of FDG PET/CT and ultrasound did not differ significantly (p=1.000). In combined modalities of FDG PET/CT and ultrasound, the sensitivity was 81.3% and higher than that of FDG PET/CT, ultrasound (p<0.001, p<0.001, respectively). The median SUVmax of pathologically positive node levels was 5.64±3.11 (range 1.4∼22.5) and that of pathologically negative node levels was 3.31±3.23 (range 1.2∼14.2)(p=0.039). Conclusion: The combination of FDG PET/CT and ultrasound improves cervical staging of PTC that are often not found if only one imaging modalities are applied.
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구강 및 구인두 편평상피암종의 림프절 전이에 대한 PET-CT 영상의 유용성
주영훈(Young-Hoon Joo),선동일(Dong-Il Sun),박준욱(Jun-Ook Park),유이령(Ie-Ryung Yoo),김민식(Min-Sik Kim) 대한두경부종양학회 2010 대한두경부 종양학회지 Vol.26 No.1
Objectives :We evaluated the use of FDG PET/CT for the identification of cervical nodal metastases of SCC of the oral cavity and oropharynx with histological correlation. Material and Methods :We reviewed 46 medical records, from January 2004 to July 2007, of patients who underwent FDG PET/CT and CT/MRI for SCC of the oral cavity and oropharynx before surgery. We recorded the lymph node metastases according to the neck level affected and the system used for the imaging-based nodal classification. Results :The FDG PET/ CT had a sensitivity of 75.6% and a specificity of 96.7%;it had a higher sensitivity than the CT/MRI for identi-fication of cervical metastases on the side of the neck(26/28 vs. 20/28, p=0.031) and at each of the cervical levels(34/45 vs. 26/45, p=0.008). There was a significant difference in the SUV max between the benign and malignant cervical lymph nodes(3.31±3.23 vs. 4.22±2.57, p=0.028). The receiver-operating-characteristic (ROC) curve analysis for differentiating the benign from the malignant cervical lymph nodes, showed that the area under the curve(AUC) of the FDG PET/CT was 0.775. The cut-off value for the SUV max was 2.23 based on the ROC curve. There was a significant correlation between the SUV max and the size of the cervical lymph nodes(Spearman r=0.353, p=0.048). Conclusion :FDG PET/CT images were more accurate than the CT/MRI images. In addition, the SUV max cut-off values were important for evaluating cervical the cervical nodes in the patients with SCC of the oral cavity and oropharynx.
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