신세포암에서 림프절절제술의 역할

유탁근(Tag Keun Yoo),조정만(Jung Man Cho) 대한비뇨기종양학회 2007 대한비뇨기종양학회지 Vol.5 No.2

로봇 보조 복강경 방광적출술 및 요로전환술의 초기 경험

조희주(Hee Ju Cho),신순철(Soon Cheol Shin),서도영(Do Young Seo),민동석(Dong Suk Min),조정만(Jeong Man Cho),강정윤(Jung Yoon Kang),유탁근(Tag Keun Yoo) 대한비뇨기종양학회 2012 대한비뇨기종양학회지 Vol.10 No.1

Purpose: Robot assisted laparoscopic radical cystectomy (RARC) is one of the options for minimal invasive treatment of muscle invasive bladder cancer or uncontrolled non muscle invasive bladder cancer. We detailed our operative techniques and initial experiences of robot assisted laparoscopic radical cystectomy with urinary diversion. Materials and Methods: From April 2010 to December 2011, 10 consecutive patients with bladder cancer who were performed robot assisted laparoscopic radical cystectomy with urinary diversion were enrolled. Patient’s demographics, intra-, perioperative data and oncologic outcome were analyzed. Urinary diversions including 9 ileal conduit and 1 ileal orthotopic neobladder were underwent extracoporeally. Results: Mean patient age was 65.1 years. The mean body mass index was 22.7kg/m². The mean operation time was 588.1min including 319.5min for robot assisted laparoscopic cystectomy (RARC), 165.0min for extracorporeal urinary diversion and 53.1min for lymph node dissection. The mean estimated blood loss was 244.7ml. The mean number of retrieved lymph node was 17.2. The pathologic report showed transitional cell carcinoma in all cases and adenocarcinoma of prostate in 2 male patients. No intra-operative complication was occurred. Conclusions: Robot assisted laparoscopic radical cystectomy could minimize surgery related complications without jeopardizing oncologic outcome. RARC may be effective treatment option for advanced bladder cancer.

세포독성 항암화학요법을 받을 수 없는 환자에서의 Estramustine Phosphate 단독요법

류재현(Jae Hyun Ryu),김상진(Sang Jin Kim),김윤범(Yun Beom Kim),정태영(Tae Young Jung),문경태(Kyong Tae Moon),조정만(Jeong Man Cho),유탁근(Tag Keun Yoo) 대한비뇨기종양학회 2020 대한비뇨기종양학회지 Vol.18 No.2

Purpose: To investigate whether estramustine phosphate (EMP) monotherapy is applicable to castration-resistant prostate cancer (CRPC) patients who cannot receive cytotoxic chemotherapy. Materials and Methods: This retrospective single-arm study was conducted in CRPC patients who had not experienced cytotoxic chemotherapy and received EMP monotherapy (560 mg/day) at 2 institutions from 2008 to 2017. We analyzed prostate-specific antigen (PSA) responses, overall survival, and adverse effects of EMP treatment. Results: A total of 28 patients were analyzed. A reduction in serum PSA was observed in 11 patients (39.3%). Seven cases (25.9%) achieved more than 25% reduction of PSA, and 5 of them (18.5%) experienced more than 50% reduction. Median overall survival was 23 months (interquartile range, 10-60 months). Multivariable analyses demonstrated that low level of PSA at diagnosis of CRPC and long duration of prior androgen deprivation therapy were independent favorable factors predicting long-term overall survival. Adverse effects were edema (n=2; grade 2), nausea/vomiting (n=1; grade 2), gynecomastia (n=1; grade 2), and dyspnea (n=1; grade 1). Neither thromboembolic event nor grade 3-5 toxicity was observed. There was no discontinuation caused by side effects of EMP. Conclusions: EMP monotherapy could be considered as a safe treatment option with some effectiveness for CRPC patients who did not undergo cytotoxic chemotherapy. EMP is not generally recommended anticancer drug in the current guidelines for CRPC, but EMP monotherapy is thought to have an alternative role when a standard treatment cannot be selected due to patient"s age, health condition, or comorbidity.

二重歸還方式을 理用한 廣帶域 增幅回路의 設計

田炳實,趙正萬,김종교 全北大學校 1978 論文集 Vol.20 No.-

Many advantages are to be obtained from the use of negative feedback, at the cost of gain. These are as follows; the increase of frequency band-width, the improvement of amplification stability, the decrease of nonlinear distortion and noise, and the simplicity of impedance matching, etc. Many of electronic devices require wide frequency bands. For example, a cathode-ray oscilloscope, in order to cover the frequency range of 0 to 20 MHZ, requires an amplifier with the frequency band over 20 MHZ. Moreover, communication devices require the very wide frequency bands of several hundreds MHZ. A negative feedback is used widely in order to obtain the devices with wide frequency bands. This paper describes the analysis and the practical synthesis procedure of the design of shaped gain, wide-band, impedance matched, dual loop feedback amplifier that uses a cascade of two common emitter transistor stages. An amplifier is designed to have the lower cut-off frequency of 50MHZ. Experimental results are coincident to the specified characteristics as well.

自動 電話機의 Push-Button式 Dial Pulse 送出機의 設計

田炳實,趙正萬,金種皎 전북대학교 공업기술연구소 1978 工學硏究 Vol.8 No.-

The existing automatic telephone causes many troubles in dialling because its structure is mechanical. In this paper, a design example of pushbutton type dial pulse transmitter of the automatic telephone which has no mechanical trouble, is presented and discussed. It reduces dialling time, normalizes dial pulse, decreases dial troubles, increases the life of telephone dial and automatic telephone exchange, and prevents us from wasting the fee for a telephone call.

車輛用 油類節減器의 實用化에 關한 硏究

姜錤文,田炳實,郭勳星,趙正萬 전북대학교 공업기술연구소 1978 工學硏究 Vol.8 No.-

Automotive fuel economizer problem is the matter of the world in energy crisis especially. The problem is more severe in our country because our country can not produce any raw petroleum. For saving petroleum and reducing automobile pollution, a fuel economizer of vehicle is an indispensable device. There are many active studies on fuel economizer of vihicle all of the world to solve the above serious problem. One of the dominant result of the studies is the development of capacitive discharge ignition(CDI)system. But the caracteristics of the CDI system have yet been getting more and more improved. In this study a CDI system is designed and tested for the practical use. 1) Area for field test For the measurement of the average rate of fuel reduction, the test car was run on the following: a) the express high way of Jeonju-Jeongeup-Kwangju-Shooncheon, Jeonju-Deajon-Cheonhju-Choongju. b) the high way of Jeonju-Goonsan. c) the pavement road of Jeonju-Namwon. 2) Testing system A car used for the measurement was the new type of Brisa('77 year type). Distance meter for the system was the attached meter to the Brisa. A stop watch made by Breiling Sprint of Swiss was used for the measurement of running hour. A fuel meter made bu Nissan Diesel Co. was used. 3) Measurement of the life of the CDI system. When an automobile electronic device is designed some kinds of special consideration are given to heat sinking, mechanical vibration and impact. All kinds of tests must be performed on thos viewpoints. The designed sustem had been tested for nine months. But any kinds of defects had not found. Following are summarized as the results for the CDI system of trial manufacture: 1) The rates of average saving fuel by using the CDI system are 60% under the speed of km/hr and 23% at the speed from 40 km/hr to 90 km/hr and 60% upper the speed of about 90 km/hr. 2) The car with the CDI system was accelerated more easily than the car without the system. 3) The life-time of spark plug and point contactor was extended by using the CDI system. 4) CO gas was exhausted from the car with the CDI system less than the car without the system.