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미세유로 내에서 Pseudomonas aeruginosa의 유영 운동 분석
장성찬 ( Sung Chan Jang ),정현호 ( Heon Ho Jeong ),이창수 ( Chang Soo Lee ) 한국화학공학회 2012 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.50 No.4
This study presents the effects of micro-geometries on the swimming behavior of Pseudomonas aeruginosa. First, we have measured parameters of single-cell motility including cell speed, run duration time, and tumble angle under two dimensional space, The results are used to calculate motility coefficients in the width of microchannels ranging from 10 to 100μm, Since the single-cell motility parameters measured depend on the interaction of flagella with the microchannel wall, the duration time of the running cell in restricted geometries is distinctively different. Therefore, the motility of bacteria is decreased by restricted geometries. This study suggests that microfluidic approach is useful tool for the analysis of bacterial motility under the restricted space and rapid analytical tool.