http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김순희 ( Sun Hee Kim ),강한철 ( Han Chul Kang ),노경희 ( Kyung Hee Roh ),김현욱 ( Hyun Uk Kim ),이경렬 ( Kyeong Ryeol Lee ),김원용 ( Won Yong Kim ),박종화 ( Jong Hwa Park ),정인식 ( In Sig Chung ),김종범 ( Jong Bum Kim ) 한국국제농업개발학회 2015 韓國國際農業開發學會誌 Vol.27 No.2
Most of pharmaceutical proteins are usually produced by the animal, insect cell and yeast culture. The proteins must be produced in strictly controlled-facilities, which is one of major causes for increasing production cost. So, in spite of increasing demand on the proteins in worldwide, their generalization has been very restrictive. To decrease the production cost, many scientists have been interested in production of pharmaceutical proteins by using the plant system for a long time. The plant system must be alternative production means, for it is easily scalable, more production cost effective, and safer than animal system. For this purpose, several techniques have been developed: stable expression by transformation of nuclear and chloroplast genome and transient expression by viral vectors. Among them, the deconstructed viral vector system has made it possible to produce recombinant proteins massively, rapidly, and transiently. So, the plant viral expression systems might be a suitable platform for production of pharmaceutical proteins in plants. In this review, we will describe the plant viral vector systems and their application.