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      • KCI등재

        구강 편평상피세포암의 처치와 예후에 관한 임상적 연구

        정인교(ln Kyo Chung),김태규(Tae Gyu Kim),김종렬(Jong Ryeol Kim),양동규(Dong Gyu Yang),신상훈(Sang Hun Shin),정기돈(Gi Don Chung) 대한구강악안면외과학회 1996 대한구강악안면외과학회지 Vol.22 No.2

        This study is aimed to improve the treatment, early diagnosis, prevention and prediction in propgnosis of oral and maxillofacial malignant tumors. The authors investigated about clinincal and histopathologic findings, treatments in 52 cases and survival rate of 23 cases to have been diagnosed and treated in the Department of Oral and Maxillofacial Surgery, College or Dentistry, Pusan National University from the 1st of January, 1986 to the 31th of September, 1993. The results were as follows: 1. Oral and maxillofacial malignant tumors occurred the most between 60~69 years of age and more often in males than females with a ratio 2.5 : 1.71% of patients were visited 3 months after onset of initial symptom and the tumors occurred the most in Stage Ⅳ with 51.9% as 27cases. 2. Surgical therapy was used the most as single therapy. Combined therapy for malignant tumor was executed more than single therapy in Stage Ⅲ, Ⅳ advanced tumor. Surgical and radiation was combined most frequently. 3. Regional neck dissection was operated most frequently for cervical neck nodes. 4. Overall 5 year survival rate of the patients possible to be investigated was 26% and overall 3 year survival rate was 43.5%. 5. The authors considered that higher stage of tumor, existence of combined disease, male than female coued be predicted poor prognosis but not in cell differentiation and age.

      • KCI등재

        골결손부 재생에 있어서 Fibrin Sealant의 효과에 대한 실험적 연구

        노철민(Cheol Min Noh),윤옥근(Ok Geun Yoon),정인교(ln Kyo Chung) 대한구강악안면외과학회 1997 대한구강악안면외과학회지 Vol.23 No.3

        Recent development of maxillofacial surgery has taken an interest in the regeneration of facial bone defects. For the reconstruction of facial bone defects, autogenous bone grafts have been widely used However, there arc some clinical problems : the morbidity of donor sites, resorption of autogenous bone graft and, the availability of the proper form and size. The purpose of this study is to find the effective solutions to above problems. The present study was designed to evaluate the roles and regenerating capacity of fibrin sealant. Fibrin sealant 1s a newly developed substance for hemostasis, tissue sealing and wound healing. I made the experimental study on the effects and roles of bibrin sealant in sutogenous bone graft procedure to minimize the above complications and problems. Twenty-five abult white rabbits were used as the experimental material. Three trephine defects were made by drilling on the parietal bone of each rabbit. Defect size was 8×8mm. First group consisted of the rabbits which had the artificial defect on the parietal bone as control. The defect in second group was sealed up with autogenous boen chip only. Last group comprised the rabbits autografted by mixing the bone chip with the fibrin sealant. The results were carefully examined grossly and microscopically from the 3rd day to the 28th day postoperatively. The following results were obtained ; 1. The mixture of fibrin sealant and bone chip was useful for regenerating the bone defects. Most of the defects were substituted by new bone. 2. In the case of the graft with bone chip only, most defects were also filled with new bone, but less than fibrin group. 3. In the control group, new bone was formed around the peripheral area only. A mixture of fibrin sealant and autogenous bone chip plays an effective role in forming new bone. And Judging from the results of this experiment, it may be expected the much use of the fibrin sealant in maxillofacial orthopedic surgery.

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