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전정애(Jungae Jeun),조희준(Hee Joon Cho),전희진(Hee-jin Jun),이지혜(Ji Hae Lee),가요요(Yaoyao Jia),조경상(Kyoung Sang Cho),김은수(Eun Soo Kim),이성준(Sung-Joon Lee) 한국식품과학회 2011 한국식품과학회지 Vol.43 No.3
We examined the in vitro mutagenic and antimutagenic effects of hexane-extracted hemp (Cannabis sativa L. subsp. sativa var. sativa) seed oil (HO) with and without S9-mediated metabolic activation, using the TA98 and TA100 Salmonella Typhimurium strains. The MTT assay revealed no cytotoxicity in HepG2 cells for HO quantities <400 g/mL. In the mutagenicity test, revertant colonies did not exceed spontaneous colonies in number. Colony numbers did not increase in either strain after HO treatment, with or without metabolic activation. HO showed no mutagenic effects and did not induce a mutation in either strain. In the antimutagenicity test, HO reduced the number of mutated colonies induced by 4NQO in both strains. The inhibition rates of HO (TA98, 21-91%; TA100, 21-85%) indicated a potent reduction in mutagenicity induced by 4NQO. HO showed no significant mutagenicity and may have antimutagenic effects, as assessed by Ames testing.
신장이식환자를 위한 약물교육프로그램이 약물에 대한 지식과 약물복용 이행도에 미치는 효과
장정주(Jang, Jeong Ju),전정애(Jeun, Jeong Ah),박정숙(Park, Jeong Sook),성은혜(Sung, Eun Hae),김혜림(Kim, Hye Rim),조아람(Jo, A Ram) 계명대학교 간호과학연구소 2017 계명간호과학 Vol.21 No.1
Purpose: The purpose of this study was to analyze the effects of the drug educational program on knowledge and medication compliance for kidney transplantation patients. Methods: Kidney transplantation patients were recruited from a transplantation center, at a university hospital located in D city, Korea. Data were collected from June 18m 2016 to september 30, 2016. The research design was a nonequivalent one group pre-posttest. Nineteen subjects participated twice in a drug educational program given by the researcher. Results: After the intervention, the participants showed a significant increase in medication knowledge (t=-7.074, p<.001) and medication compliance (t=-4.553, p<.001) than before the intervention. Conclusion: The research findings suggest that a drug education program can be used as an effective nursing intervention for kidney transplantation patients.