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      저자 : 전순신 ( Soon Shin Jeon ) (검색결과 2 건)
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        증례보고 : 경접형동 뇌하수체 종양 절제술 중 Fibrine Glue 사용 후 Aprotinin으로 인해 발생한 아나필락시스양 반응 -증례보고-

        전순신 ( Soon Shin Jeon ),최용우 ( Yong Woo Choi ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.52 No.6

        Recently fibrin glue, a hemostatic or adhesive material has been used worldwide in surgical procedures. There have been only limited numbers of reports on anaphylaxis following the topical use of fibrin glue. Here, we experienced an anaphylactoid reaction during transsphenoidal removal of pituitary tumor after local application of fibrin glue including aprotinin. Unexpected hypotension and erythematous eruptions on whole body developed suddenly after packing of it at operation field. Treatment with aggressive volume replacement with vasoactive agents and steroids were done immediately on the diagnosis of anaphylactoid reaction and patient recovered without any complications. (Korean J Anesthesiol 2007; 52: 715~8)

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        실험연구 : 출혈성 쇼크에서 Phenylephrine이 심장작업수행능력과 심근산소균형에 미치는 영향

        황병현 ( Byung Hyun Hwang ),홍성진 ( Sung Jin Hong ),전순신 ( Soon Shin Jeon ),최진환 ( Jin Hwan Choi ),이해진 ( Hae Jin Lee ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.52 No.5

        Background: The issue of using phenylephrine in hemorrhagic shock treatment has been controversial because it is known that phenylephrine improves the tissue perfusion by increasing arterial blood pressure but deteriorates the myocardium by increasing afterload and decreasing myocardial oxygen delivery via coronary vasoconstriction. This study was aimed to assess the effects of phenylephrine on hemodynamic variables, cardiac performance, and myocardial oxygen balance in resuscitation from hemorrhagic shock. Methods: Twenty anesthetized dogs were randomly divided into phenylephrine group and control group. After inducing hemorrhagic shock, resuscitation was done with phenylephrine and 0.9% normal saline respectively. We measured hemodynamic indices, blood gas parameter and cardiac enzymes which indicate myocardial demage. Results: In both groups, cardiac output and hemodynamic indices improved. In phenylephrine group, the systemic oxygen delivery and consumption was much higher and the myocardial oxygen extraction ratio was maintained at the lower level than the control group. In addition, the CK-MB was higher at the early phase of resuscitation and the troponin T was also higher than the control group during the whole period of resuscitation. Creatine kinase-MB increased during early resuscitation in phenylephrine group but kept decreasing after that and there`s no difference between two groups. Troponin T was higher in the phenylephrine group after resuscitation. Conclusions: We concluded that phenylephrine improves myocardial oxygen balance and contractility without serious myocardial demage during resuscitation from hemorrhagic shock. (Korean J Anesthesiol 2007; 52: 571~7)

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