http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
甲狀線 分化癌의 방사성 요드-131 治療에 대한 臨庶的 考察
박윤규(Yoon Kyu Park),이대영(Dae Young Lee),전성은(Seong Eun Chon),오성수(Sung Soo Oh),정을삼(Eul Sam Chung) 대한두경부종양학회 1996 대한두경부 종양학회지 Vol.12 No.1
This study was desinged to evaluate the effect of radioactive iodine-131 therapy in differentiated thyroid carcinoma treated at the Presbyterian Medical Center, Chonju during the 20-year period from 1975 to 1994. The authors reviewed 246 patients who received radioactive iodine-131. An analysis of the therapeutic response and survival rates of the 246 patients has been carried out. The male to female ratio was 1 : 3.6. The peak incidence was in the 4th and 6th decades. The histologic findings in the 246 patients were papillary adenocarcinoma in 200 cases, follicular adenocarcinoma in 29 cases, mixed type in 14 cases, and others in 3 cases. Combined treatment modalities of 246 patients consisted of sugery and radioiodine in 222 cases, surgery with radioiodine and external irradiation in 11 cases, and surgery with radioiodine, external irradiation and chemotherapy in 5 cases. 42 of the 246 cases showed recurrence and the commonest type of combined treatment for recurrent case was surgery followed by radioiodine-131. The highest accumulated total dosage of radioiodine-131 was 480mCi in that case femoral metastasis was noticed. The most common locoregional metastatic site was ipsilateral cervical node, and neighbouring muscle, vessel, trachea, recurrent layngeal nerve, in order of frequency. The determinate 10-year survival rate was 91.8% in the group receiving surgery followed by radioiodine-13l and 71.4% in patients receiving surgery, radioiodine-13l with XRT. The determinate 10-year survival rate was better for patients under 40 years of age who received radioiodine as compared to patients over 40 year of age(85.7% vs. 33.3%). The most usual primary therapeutic dosage in the group of cervical lesion was 90120mCi after surgery.
이삼열(Sam uel Lee),이석재(Seug Zae Lee),이혁진(Hyouk Jin Lee),전성은(Seong Eun Chon),박윤규(Yoon Kyu Park) 대한두경부종양학회 1994 대한두경부 종양학회지 Vol.10 No.2
1) 선천성 갑상선 발육이상 환자 9명 모두, 경부종피를 호소하였으며, 이 중 1예는 연하통을 동반하였다. 2) 선천성 갑상선 발육이상을 세분하여보면, 이소성갑상선이 44.4%,편측발육부전 및 이소성갑상선을 동반한 경우가 33.3%였고, 편측발육부전을 보인 경우가 22.2%였다. 3) 이소성갑상선을 위치별로 보면 설기저부가 6예(85.7%-1예 중복됨), 갑상설관이 2예였다. 4) 정상 갑상선기능을 보인 경우가 77.8%였고, 갑상선기능저하증을 보인 경우가 22.2%였다. 정상기능을 보인 7명의 환자 중 4명에서 갑상선자극호르몬(TSH)이 증가되어 있었다. 5) 총 9명중 7명에서는 갑상선억제요법만 시행하였고, 2명에서는 갑상선억제요법에 반응하지 않아 절제술을 시행하였으며, 2명 모두 설갑상선이었다. 수술후 계속적으로 갑상선호르몬을 복용중이다. Congenital thyroid dysgenesis including agenesis, hypoplasia and ectopia is the predominant cause of permanent hypothyroidism. Of these, two thirds are due to an ectopic thyroid and about one third to complete thyroid agensis. From Jan. 1981 to Dec. 1992, authors experienced the 9 cases of congenital thyroid dysgenesis. Aberrent thyroid was 4 cases (44.4%), thyroid hemiagenesis with aberrent thyroid was 3 cases(33.3%) and thyroid hemiagenesis was 2 cases(22.2%). The most predominant site of aberrent thyroid is the base of tongue(85.7%). 7 patients(77.8%) revealed euthyroidism and among them, 4 patients showed elevated TSH level. Hypothyroidism was 2 patients (22.2%). 7 cases responded to thyroid suppressive therapy. 2 cases of lingual thyroid which did not responed to thyroid suppressive therapy underwent surgery and they have placed on thyroid suppressive therapy postoperatively.