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RISS 인기검색어
- 검색키워드
- 저자 : 전길자 ( Young Sook Kim (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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High Levels of Protein Carboxyl Methyltransferase in Abnormal Tissues and Changes of its Isoenzymes
김영숙,전길자,Kim, Young-Sook,Jhon, Gil-Ja 생화학분자생물학회 1988 한국생화학회지 Vol.21 No.4
정상 혈액, 위, 유방조직 및 당뇨병 혈액, 위암, 유방암 조직에서 protein carboxyl methyltransferase의 활성도를 비교 측정하였고, 각각에서 그 isoenzyme의 변화를 관찰하였다. 그 결과 protein carboxyl methyltransferase의 활성도가 당뇨병 혈액, 위암, 유방암 조직에서 그 정상과 비교해서 약 2-5배 증가됨을 볼 수 있었고 isoenzyme의 분포가 정상과 비정상에서 다르게 나타났다. 이러한 결과로 protein carboxyl methyltransferase의 활성도 측정 및 그 isoenzyme의 변화 양상이 질병을 진단하는 데 이용될 가능성을 제시할 수 있다. The levels of protein carboxyl methyltransferase, an enzyme that methylates free carboxyl groups of altered protein and its isoenzymes were determined in normal and abnormal tissues (normal blood, diabetic blood, normal stomach and its tumor, normal breast and its tumor). Protein carboxyl methyltransferase activities were higher in the diabetic blood and the tumors than in their normal tissues. The distributions of protein carboxyl methyltransferase isoenzymes in normal tissues were different from in abnormal tissues. These results suggest the measurements of PCM activity and its isoenzymes offer a possible clinical diagnosis.
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비정상 조직에서 Protein Carboxyl Methyltransferase 의 활성도 및 그 Isoenzyme 의 변화에 관한 연구
김영숙,전길자 ( Young Sook Kim,Gil Ja Jhon ) 생화학분자생물학회 1988 BMB Reports Vol.21 No.4
The levels of protein carboxyl methyltransferase, an enzyme that methylates free carboxyl groups of altered protein and its isoenzymes were determined in normal and abnormal tissues (normal blood, diabetic blood, normal stomach and its tumor, normal breast and its tumor). Protein carboxyl methyltransferase activities were higher in the diabetic blood and the tumors than in their normal tissues. The distributions of protein carboxyl methyltransferase isoenzymes in normal tissues were different from in abnormal tissues. These results suggest the measurements of PCM activity and its isoenzymes offer a possible clinical diagnosis.
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