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임성윤 ( Chi Ryang Chung ),( Kyeongman Jeon ),( Sang-bum Hong ),( You Na Oh ),( Sang-min Lee ),( Woo Hyun Cho ),( Sunghoon Park ),( Yeon Joo Lee ),( Young-jae Cho ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Introduction: The recirculation during veno-venous extracorporeal membrane oxygenation (VV ECMO) had been a drawback, which could limit sufficient oxygenation. Purpose of this study is to compare the short-term oxygenation and long-term mortality in acute respiratory distress syndrome (ARDS) patients under VV ECMO according to their cannula configurations, especially in the national environment of the absence of newly developed double-lumen, single cannula. Methods: Data were retrospectively analyzed from the severe ARDS patients receiving VV ECMO from 2012 to 2015 at six hospitals. Primary outcomes were PaO2 at 1, 4, and 12 hours after initiation of ECMO and 180-day their mortality. Results: We included 354 patients and divided them into two groups according to the sites of return cannula; 193 patients were cannulated to femoral vein, and 161 patients to internal jugular vein. Baseline characteristics at admission including PaO2 were similar between two groups. PaO2 in 1 hour of the femoral group was higher than the jugular group (190.3 vs. 160.0, P=0.108), however, there was no significant difference in the increments of PaO2 including 4 and 12 hours after initiation of ECMO between two groups. Mortality rate at 180 days after ECMO was not significantly different by the site of cannulation. Mechanical or infectious complications in terms of cannulation also did not show significant difference. Conclusion: Regardless of cannula configurations, ARDS patients under VV ECMO showed comparable clinical outcomes. Further randomized control trials should be warranted.