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百子附歸丸이 寒冷스트레스 白鼠의 子宮內膜變化에 미치는 影響
李惠珍,李寅仙 대한한의학회 부인과학회 2000 大韓韓方婦人科學會誌 Vol.13 No.2
This study is performed to investigate whether Backjabugui-Hwan have an effect on the endometrial change in the cold stressed rats. Rats are exposed to cold environment for 20days and administered orally with Backjabugui-Hwan. On days 5, 10, 15 and 20 after exposure to cold environment, the change endometrial GC was observed with histochemical stain and those in c-fos and c-jun observed with immunohistological stain. The result was as follows. The level of GC and c-fos was shown to be increased and thus normalized in the sample group compared with control group, while that of c-jun was shown to be decreased and thus normalized in the sample group compared with control group. In conclusion, this study suggest that Backjabugui-Hwan may have a normalizing effect on the response to cold stress in endometria of rats