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RISS 인기검색어
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- 저자 : 이일주 ( Chang Eui Hong (검색결과 2 건)
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홍창의,이일주,김수찬,서경 ( Chang Eui Hong,Il Joo Lee,Soo Chan Kim,Kyung Seo ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1
Impetigo herpetiformis is a form of pustular psoriasis that occurs during pregnancy and may be life-threatening. The pathogenesis and etiology of impetigo herpetiformis is not clear, but several reports have associated onset of this disorder with hypocalcemia, hypoparathyroidism, and the use of oral contraceptives. The typical lesions are erythematous patches that are studded with tiny superficial pustules particularly coalescing at their margins causing pain, and a burning sensation. Laboratory findings include an elevated erythrocyte sedimentation rate, increased peripheral blood leukocyte counts, hypoalbuminemia, and in severe cases, hypocalcemia. The histopathology is the same as that of pustula psoriasis. Our patient, a 31 year-old female (Intra Uterine Pregnancy 28 weeks), was admitted to our hospital due to generalized skin eruption and severe constitutional symptoms. Her clinical features, laboratory and histopathologic findings were compatible with that of impetigo herpetiformis. In spite of our all efforts, intrauterine fetal death was noted at her 33rd week of pregnancy. We report a case of impetigo herpetiformis terminating in fetal death with the review of literature. {Kor J Dermatol 1997;35(1): 150-154}
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다형 홍반의 임상 및 병리조직학적 특성 - 수장족저부 병변과 비수장족저부 병변의 임상 및 병리조직학적 비교 -
홍창의,한승경,이광길,이일주 ( Chang Eui Hong,Seung Kyung Hann,Kwang Gil Lee,Il Joo Lee ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.6
Background: Erythema multiforme is an inflammatory disorder of the skin which may be characterized by erythematous papules, plaques, vesicles, and 'target-like' annular lesions. Mucosal lesions may occur. Symmetric irivolvement of the extrernities, especially the dorsurn of the hands and feet, and face is the classic: pattern of cutaneous distribution. Palmoplantar lesions of erythema multiforme are relatively uricornmon. Objective : Our purpose was to investigate the clinical and histopathological r,haracteristics of erythema multiforme involving the palm and sole. Methods : Thirty one cases of erythema multiforme involving the palm and sole, and thirty cases involving other sites wer collected and analysed with particular reference to epidemiological data, type and distribution of the skin lesion and histopathological characterist,ics. Results : 1. The median ages of both groups were the early thirties. There were no sexual predominances. 2. The clinical features of erythema multiforme involving the palm and sole were relatively mild and showed atypical skir, lesions including macules and papules compared with erythema multiforme involving the other sites. 3. The histopathological changes of the palmoplantar group were also mild, especially the epidermal changes which included keratinocytes necrosis, subepidermal blisters, focal parakeratosis, extensive epidermal necrosis and xocytosis etc. 4, The most import,ant and consistent histopathological finding of the palmoplantar erythema multiforme group was lymphoc;yte tagging along the basernent membrane, which was found consistently apart from one case. Conclusion : We investigated the clinical and histopathological features of erythema multiforme involving the palm and sole. They showed mild clinical features and atypical skin lesions cornpared with other group. The histopathological spectrum of this group was diverse, and reflected the early stage of pathomecha nisms of erythema multiforme. Among them, lyrnphocyte tagging was the most important and censistent finding in palmoplantar erythema multiforme. (Korean J Dermatol 1997;35(6): 1159-1167)
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