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한국인 표피 Langerhans세포의 분포에 관한 연구
원문섭,장진요 중앙대학교 의과대학 의과학연구소 1984 中央醫大誌 Vol.9 No.4
The author has studied to investigate the distribution of epidermal Langerhans cells in the various regions of the body, age and sex differences as well as the fine structural characteristics of the cell. One hundred eighty two skin specimens were obtained by biopsy or surgery from various regions of the body. The epidermal sheets separated from the dermis were reacted with OKT_6 monoclonal antibody and horse radish peroxidase conjugated goat anti-mouse immunoglobulin, and followed by enzyme histochemistry using 3,3'-diaminobenzidine and hydrogen peroxide. The statistical analysis of epidermal Langerhans cell counts and the electron microscopice observation were summarized as follows: 1. The average epidermal Langerhans cell counts were 667 cells/㎟ in young group, 771 cells/㎟ in the adult group. This difference of cell counts between young and adult group was proved to be statistically significant. 2. The epidermal Langerhans cell counts varied with regions of the body. In the adult group, the abdomen and back were among those of highest cell counts followed by the neck, arm, groin and perineum, thigh, face, forearm, leg and prepuce in decreasing order. The cell count of the prepuce was significantly lower, while those of the abdomen and back were significantly higher than those of other regions. In the young group, there was no significant regional difference in epidermal Langerhans cell counts except the prepuce which found significant lower. 3. No significant sex difference of epidermal Langerhans cell count was observed in both young and adult groups. 4. Langerhans cells were revealed as characteristic dendritic cells by OKT_6 monoclonal antibody and enzyme histochemistry. 5. In electron microscopy, epidermal Langerhans cells were distinguished from the surrounding keratinocytes by the presence of peculiar rod-shaped structures and small vesicles in the cytoplasm which had no tonofilaments.
원문섭(Moon-Seob Won) 한국항공우주학회 2019 韓國航空宇宙學會誌 Vol.47 No.5
본 논문의 목적은 항공기에 장착되는 복합재 라미네이트 및 샌드위치구조를 가지는 레이돔에 대한 조류충돌해석을 수행하고 해석결과와 시험결과를 비교 및 분석하기 위함이다. 먼저 SPH(Smoothed Particle Hydrodynamics)법을 통해 물의 특성을 가지는 조류를 모델링하였으며, 조류충돌 시험을 통해 조류가 충돌할 때의 속도를 입력하여 조류충돌해석을 수행하였다. 해석결과를 통해 레이돔의 파손 여부를 조사하고 최대 변형량을 시험결과와 비교하였으며 충돌과정에서의 압력변화추 이가 기 연구되었던 결과와 일치함을 확인하였고, 이를 통해 수치해석모델의 신뢰성을 확보하였다. 또한 조류모델을 이루는 입자의 밀도가 레이돔의 파손 형상에 영향을 미친다는 사실을 확인하였다. The main purpose of this study is to compare the bird strike analysis result of the radome composed of composite laminate and sandwich structure attached to aircraft with test result. First of all, we generated bird model which has water properties through SPH(Smoothed Particle Hydrodynamics) method. And then bird strike analysis was conducted with initial velocity of bird measured from bird strike test. From analysis result we investigated whether structural failure occurred or not onto the radome and compare maximum displacement of the radome structure with test result. Also reliability of numerical analysis model was confirmed through time-dependent pressure trend on this collision process matched existing research result. Furthermore, we confirmed that failure behavior of the radome can be affected by density of the particles in the bird model.
송계용,노병인,원문섭,최문섭,장진요 대한피부과학회 1982 大韓皮膚科學會誌 Vol.20 No.3
Basal cell epithelioma arising from epidermis and its appendages is a common skin tumor. But multiple occurence of basal cell epitheliomas and that of arising in an epidermal nevi are extremely rsre. Since the first report by Toyama and Kojima in 1937, only few cases were reported in the world literatures. We observed a case of multiple basal cell epitheliomas arising in an epidermal nevi in a 54-year-old female patient who had rhomboidal verrucous patch on the right side of the cheek and arciform erythematous verrucous eruption from the right side of the eyebrow to the lower eyelid. Clinical features were not compatible with any type of basal cell epithelioma. But histological finding revealed basal cell epithelioma with epidermal nevi. Literatures were briefly reviewed.
노병인,장진요,원문섭 대한피부과학회 1981 大韓皮膚科學會誌 Vol.19 No.6
Cheilitis granulomatosa is a macrocheilia having a sudden onset and a progresaive eourse that terminates in chronic enlargement of the lips. Labial enlargement can occur alone or in combination with intermittent facial paralysis and fissured tongue. The traid of abnormalities has been termed the Melkersaon-Rosenthal syndrome. The term, cheilitis granulomatosa, is now generally accepted as the description of the labial conditian with or without the other components of the triad. We have experiegced a case of cheilitis granulomatosa in a 23-year-old man and excellent result were obtained after local triamcinolone acetonide injections. On the first examination, the upper lip was estimated at approximately twice the normal size and the tongue was moderatedly furrowed. The consistency was elastic, but firm due to the nan pitting edema of the entire upper lip. We have treated him with intralesional injections of triamcinolone acetonide. Total injeetions were fifteen times in 6 months period. After the treatment, climcally ohaerved ehanges eonsisted of a decrease in lip volume, diminished edema plus a gradual softening of lip texture.