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RISS 인기검색어
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- 저자 : 양용모(Youg Mo Yang) (검색결과 1 건)
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정지봉(Ji Bong Jeong),양용모(Youg Mo Yang),전원중(Won Joong Jeon),서정철(Jeong Chul Seo),이경수,이현희(Hyun Hee Lee),고병성(Byeong Seong Ko),채희복(Hee Bok Chae),박선미(Seon Mee Park),윤세진(Sei Jin Youn) 대한소화기기능성질환·운동학회 2000 Journal of Neurogastroenterology and Motility (JNM Vol.6 No.1
N/A Background/Aims: The purpose of this study was to discover the physiologic difference of a postprandial motor response in different segments of the colon between patients with irritable bowel syndrome and healthy subjects. Methods: Irritable bowel syndrome patients are categorized into three groups according to their main symptoms; loose stool-dominant (A, n=5), abdominal pain-dominant (B, n=5), constipation-dominant (C, n=6) and the normal control group (n=5). The intraluminal pressure activity was measured with a colonoscopically positioned multilumen manometric catheter. The change of the colonic motility index (MI) is presented as a percent change (mean±SE%) over the basal period in response to a meal. Results: 1) In the transverse, descending and sigmoid colon of healthy subjects, the percentage changes in the basal Ml during the first 30 min after the meal are significantly increased (p<0.05-0.01). 2) In the sigmoid colon, the percentage changes in the basal MI during the first 30 min after the meal were 62±18 in A, 29±18 in B, 12±8 in C and 306±l02% in heathy subjects respectively, which shows a significant difference between the MI of control and healthy subjects (p<0.05). 3) In B and C, the percentage changes in the l MI during the first 30 min after the meal in the descending colon were 105±38, 11±7, respectively, which shows a significant difference between the two groups (p<0.05). In A and C, the percentage changes in the basal MI during the first 30 min after the meal in the sigmoid colon was 62±18, 12±8, respectively, which shows a significant change between the two groups (p<0.05). Conclusion: This study suggests that postprandial intraluminal pressure differences play a role in the pathophysiology of irritable bowel syndrome. (Korean Journal of Gastrointestinal Motility 2(00;6:20-31)
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