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Transoctylene rubber ( TOR ) 의 첨가가 NR / isotactic pp 블렌드의 물성에 미치는 영향
장영욱(Young Wook Chang),양영철(Yung Chul Yang),나창운(Chang Woon Nah) 한국고무학회 2001 엘라스토머 및 콤포지트 Vol.36 No.3
N/A Thermoplastic elastomers based on dynamically vulcanized NR/TOR/PP (rubber/PP=70/30) blends were prepared in a Haake banbury mixer. Effect of TOR content on the mechanical, dynamic mechanical and thermal stability of the rubber/plastic blends was characterized by UTM, DMTA, and TGA. On the addition of traps-polyoctylene rubber(TOR) to the rubber phase, there was a decrease in compression set and increase in tensile properties, hardness and dynamic properties as well as thermal stability of the elastomeric blends. Improvements in the properties were believed to be due to an increase in crosslink density of the rubber phase and increase in homogeneity of the blends.
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김은희,이현기,양영철,차인준 인제대학교 1990 仁濟醫學 Vol.11 No.3
Se 부족에 의하여 랫트의 체중과 사료 섭취량은 감소되었으며 혈중 LDH, GOT와 간장조직의 glutathion 농도는 정상보다 증가되었다. Se 부족군의 조직학적 소견은 간세포의 공포화 변성, 간조직의 PAS 반응 저하, LDH 활성화 감소 및 ACP 활성의 증가를 나타내었으며, rER의 분절화 현상 및 감소와 mitochondria의 종창 등이 관찰되었다. The objective of this study was to determine the effect of Se-deficient diet on the weight gain, chemical changes in plasma and microstructural change of liver in rat. Rats were divided into 2 diet groups (Se-deficient diet) and control diet and sacrificed after 21days of feeding. Levees of LDB, GOT, GPT of Plasma arid glutathione of liver were determined and light microscopic and electron microscopic observation of ret liver were performed. Total weight gaits (P<0.05) and feed efficiency radio (P<0.001) were significantly lower in Se-deficient group than in control group, whereas the levels of plasma LDH (P<0.001) and GOT (P<0.05) were increased significantly in Se-deficient group. Furthermore, the levels of total glutathione (P<0.01) and reduced glutathione (P<0.001) showed significant increase in Se-deficient group. Light microscopic observations showed that cytoplasmic blooning degeneration and pyknosis of nuclei were often found around portal canal of Se-deficient group by H-E straining. PAS staining also showed weakly positive reaction around central area, whereas PAS negative reacting cells were often observed around portal canal of Se-deficient group. Histochemical staining skewed that cytochrome oxidase activity were very active in both groups, whereas LDH activity was significantly decreased arid ACPase activity was significantly increased in Se-deficient group. Electron microscopic observation showed that the number of rER were decreased and the blooning degeneration of rEr was often observed in Se-deficient group. Mitochondria with mayeline figure arid wooly density were also observed in Se-deficient group. Light microscopic observations showed that cytoplasmic blooming degeneration and pyknosis of nuclei were often found around poral canal of Se-deficient group by H-E staning. PAS staining also showed weakly positive reaction around central area, whereas PAS negative reacting cells were often observed around portal canal of Se-deficient group. Histochemical staining showed that sytochrome oxidase activity were very active in both groups, whereas LDH activity was significantly decreased and ACPase acclivity was significantly increased in Se-deficient group. Electron microscopic observation stewed that the number of rER were decreased and the blooning degeneration of rER was often observed in Se-deficient group. Mitochondria with myeline figure and wooly density were also observed in Se-deficient group.
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Selenium 부족이 흰쥐 피부조직의 형태학적 변화에 미치는 영향
조성도,양영철,차인준 인제대학교 1993 仁濟醫學 Vol.14 No.3
Torula yeast 식이를 3주 동안 공급하여 selenium부족을 유발시켰을 때 흰 쥐의 두경부에서 일률적으로 나타나는 탈모 현상을 관찰하고 이러한 탈모를 일으키는 원인기전을 규명하고자 하는 실험의 일환으로 selenium 부족 시에 피부조직의 형태학적인 변화를 관찰하였다. Selenium 부족시 두정부 피부조직의 H.&E. 염색과 PAS 염색상에서 기저세포층의 비후화, 기저 세포막의 손상 등이 광학현미경 상에서 관찰되었고, 전자현미경 상에서는 mitochondria가 종창되어 나타났으며, multivesicular body와 tonofilaments가 두꺼워진 것을 관찰할 수 있었다. 이러한 변화 양상은 극세포(spinouts cell)와 과립세포(granular cell)에서도 비슷한 변화가 관찰되었으나 그 변화의 정도는 기저세포에서 보다는 현저하지 않았다. We investigated the morphological changes of skin of Sprague-Dawley rats induced selenium deficiency by feeding Torula yeast diet for three weeks. The hypertrophy of basal cell layer interrupted continuity of basal membrane, swelling of mitochondria. multivesicular body and thickend tonofilaments were observed on light microscope and electron microscope. These changes were more prominent in the layer of basal cells than those of the spinouts cells or granular cells.
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