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아마추어 마라톤 주자에서의 마라톤 완주 전후 생화학적 골대사 지표의 변화
안재기 ( Jae Ki Ann ),김철 ( Chul Kim ) 대한스포츠의학회 2009 대한스포츠의학회지 Vol.27 No.1
It has been known that exercise has long-term benefits on bone mass, but acute effects following long distance running likes marathon were not clearly known. The aim of this study was to evaluate the acute effects of bone remodeling following full course running of marathon by measuring biochemical markers of bone turnover in blood and urine. Sixteen healthy, regularly exercising persons who participated in full course running of marathon were studied. There were 11 men and 5 women and their mean age was 35.6 year-old (range 25-45). We collected blood and urine samples in the morning preceding the race, and on days 1, 2 and 7 following the marathon. We measured biochemical bone markers including alkaline phosphates (ALP), serum osteocalcin, parathyroid hormone (PTH), serum ionized calcium, and urinary deoxypyridinoline, and then we analyzed on each times. There were no significant changes in PTH and ALP levels change at any time following the race. The serum ionized calcium levels decreased on the day after race (p<0.01). The serum osteocalcin levels decreased on the day after the race (p<0.01) and it returned to pre-race levels on second day following the race. The Serum osteocalcin levels at 1 week after the race were significantly higher than pre-race levels (p<0.01). The urinary deoxypyridinoline levels increased the day after the race (p<0.01), and then it sequentially decreased on second day after and one week after the race (p<0.01). In marathon running, bone resorption and the inhibition of bone formation occur on one day after the race. The effect of bone formation increases and the effect of bone resorption decreases on second day and one week after the race. We know that there are some changes in bone turnover markers before and after marathon racing.
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