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증례보고 : 전신마취 유도 중 발생한 Vecuronium에 의한 아나필락시스
신헬렌키 ( Helen Ki Shinn ),임현경 ( Hyun Kyoung Lim ),송장호 ( Jang Ho Song ),한정욱 ( Jeong Uk Han ),고두현 ( Du Hyun Ko ),정인준 ( In Jun Jung ),정종권 ( Jong Kwon Jung ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.55 No.5
Anaphylaxis is one of major causes of morbidity and mortality during anesthesia. Muscle relaxants are the most common cause of anaphylaxis during anesthesia. A 54-year-old woman was scheduled for thyroidectomy. She had no history of allergy and had never previously undergone general anesthesia, Lidocaine, propofol and vecuronium were injected sequentially to induce general anesthesia. Two minutes after the vecuronium injection, severe hypotension, tachycardia and bronchospasm developed, and delayed skin rashes appeared. The patient recovered without any significant complications after immediate proper intensive care. The operation was delayed and a skin test was performed on the 7th day after discharge. She revealed a positive skin test for vecuronium. The anesthesia was re-induced without muscle relaxant and maintained with propofol and remifentanil infusion. Surgery was completed uneventfully, and the patient recovered without any adverse reaction. (Korean J Anesthesiol 2008;55:613~7)