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솔잎(Pinus densiflora leaf) 추출물의 항비만효과
최민영(Min Yeong Choi),신별(Byel Shin),유주형(Ju Hyeong Yu),여주호(Joo Ho Yeo),이재원(Jae Won Lee),금나경(Na Gyeong Geum),안미연(Mi-Yun An),정진부(Jin Boo Jeong) 한국자원식물학회 2022 한국자원식물학회지 Vol.35 No.2
In this study, we measured the inhibitory activity of Pinus densiflora leaf (PDL) against excessive lipid accumulation in mouse preadipocyte, 3T3-L1 cells to investigate whether PDL exerts anti-obesity activity. Lipid accumulation and the protein level were measured using Oil red O staining assay and Western blot analysis, respectively. We observed that PDL inhibited excessive lipid accumulation and decreased the expression of CEBPα, PPARγ and perilipin-1 related to lipid accumulation in 3T3-L1 cells. Therefore, considering these results, PDL can be used as a potential agent for anti-obesity.