C5210-H(HP)와 NKT322-EH 소재의 협피치 커텍터에서 단조 가공에 의한 소재 폭 변화에 관한 연구

신미경,이춘규,Shin, Mi-Kyung,Lee, Chun-Kyu 한국금형공학회 2020 한국금형공학회지 Vol.14 No.3

As devices such as smartphones, tablet PC, and wearable devices have been miniaturized, the connectors that go into the devices are also designed to be very small. The connector combines the plug and the receptacle to transfer electricity. As devices are miniaturized, the contact shape is formed by partially thinning the thickness of the raw material of the terminal in order to lower the coupling height of the plug and receptacle. The product used in this study is a receptacle terminal used for 0.4mm pitch board to board connector among fine pitch connectors. When the material thickness is reduced by forging the receptacle terminal, the width change of the pin is checked. To reduce the thickness of the material by forging, pre-notching is applied in the first step, forging in the second step, and notching in the third step. After forming the width dimension of the pin to 0.28 mm in the pre-notching process, in the forging process, the material thickness 0.08 mm and 0.02 mm (25%) were forged and the thickness was changed to 0.06 mm and the width change amount of the pin was measured. The facility produced 10,000 pieces at 400 SPM using a Yamada Dobby (MXM-40L) press, and thirty pins were measured and the average value was shown. After forging by using C5210-H (HP) and NKT322-EH, which are frequently used in connectors, analyze the amount of change in each material. The effect of punching oil on forging is investigated by appling FM-200M, which is highly viscous, and FL-212, fast drying oil. This study aims to minimize mold modification by predicting the amount of material change after forging.

자궁경부도말에서 Atypical Squamous Cells of Undetermined Significance(ASCUS)의 조직학적 및 세포학적인 추적 관찰

신미경,Shin, Mi-Kyung 대한세포병리학회 1998 대한세포병리학회지 Vol.9 No.1

In 1988, The Bethesda System for reporting cervical and vaginal cytologic diagnoses was introduced and this was revised in 1991. The new diagnostic category "atypical squamous cells of undetermined significance(ASCUS)" introduced by The Bethesda System is an area of controversy about the diagnostic category, clinical significance and appropriate treatment. A retrospective 2 years and 9 months study(April, 1994-December, 1996) was performed to evaluate the significance of reporting ASCUS on cervical smears. Sixtyseven(1.17%) of 5,730 smears were diagnosed as ASCUS and 21 cases were followed by cervical biopsies and/or endocervical curettages in 4 cases(19%), and repeat cervical smears in 17 cases(81%). Tissue diagnoses were benign in 2 cases and squamous cell carcinoma in situ in 2 cases. Cytologic diagnosis of follow up smear were negative in 14 cases(82.4%) and persistent ASCUS in 3 cases(17.6%).

부비동과 비의 미분화 암종 - 1예 보고 -

신미경,채양석,Shin, Mi-Kyung,Chae, Yang-Seok 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.1

Sinonasal undifferentiated carcinoma(SNUC) is a distinct, relatively rare neoplasm arising in the nasal cavity and paranasal sinuses composed of undifferentiated epithelial cells and clinically characterized by a fulminant course. We report a case of SNUC in a 56-year old man who have had bilateral neck masses since one month ago before coming to our hospital. The paranasal computed tomography showed soft mass density in the left maxillary sinus and the nasal cavity with bone destruction in the anterior medial and the inferior maxillary sinus wall. This mass was extruded into the left orbital wall. Biopsy of the nasal mass and fine needle aspiration(FNA) of the neck mass were done. FNA revealed medium-sized neoplastic cells forming clusters or individually dispersed. Nuclei were round to oval, slightly to moderately pleomorphic, and hyperchromatic. Chromatin was finely granular, but occasionally was coarsely granular. Nucleoli varied from large to inconspicuous and the cytoplasm was scanty.

대두분 급여가 고지혈증 흰쥐의 지질대사 및 효소 활성도에 미치는 영향

신미경,한성희,박성혜,Shin Mee-Kyung,Han Sung-Hee,Park Sung-Hye 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.2

To investigate the effects of yellow soybean powder on serum lipid level and enzyme activities, male Sprague-Dawley(SD) rats were given hyperlipidemic diets for 6 weeks. Rats(n=8) were divided into three groups consisting the normal group(N), hyperlipidemic diets group(C) and hyperlipidemic diets and yellow soybean powder group(YSP). YSP group lowered triglyceride, total lipid, phospholpid, ester-cholesterol and free-cholesterl than control group. YSP group lowered total-cholesterol, VLDL-cholesterol and LDL-cholesterol but increased HDL-cholesterol of the serum compared to the control group. Athergenic Index(AI) and LHR(LDL-cholesterol/HDL-cholesterol ratio) of YSP group was decreased by control group (p<0.05). On the other hand, glutamic oxaloacetate transaminase(GOT), glutamic pyruvate transaminase (GTP), lactate dehydrogenase(LDHase) and alkaline phosphatase(ALP) enzymes activities were decreased by hyperlipidemic diets group (C). These results suggest that yellow soybean powder fed a lipid lowering effect in serum of rats.

대학생의 식습관과 식품선호도에 관한 조사 연구 - 전북 익산 지역을 중심으로 -

신미경,서은숙 ( Mee Kyung Shin,Eun Sook Seo ) 대한가정학회 1995 Human Ecology Research(HER) Vol.33 No.4

Heme 산화효소 발현 유도체로서 Isoflavone-Free 검은콩 펩타이드의 항고혈압 활성

신미경(Mi-Kyung Shin),권용현(Yong-Hyun Kwon),안창원(Chang-Won Ahn),신동석(Dong-Seok Shin),박수현(Soo-Hyun Park),최보화(Bo-Hwa Choi),홍순선(Soon-Sun Hong),강주희(Ju-Hee Kang),박창신(Chang-Shin Park) 대한약학회 2012 약학회지 Vol.56 No.3

We previously reported that the novel isoflavone-free peptide mixture (black soybean peptide, BSP) had several beneficial effects like antiobesity and hypotriglyceridemic effect. However, there are no reports for BSP on anti-hypertensive activity. BSP induced heme oxygenase-1 (HO-1) in HUVECs, thus investigated the HO-1-induced activity in HUVECs and the anti-hypertensive effects in SHR animal model. BSP significantly induced HO-1 expression both at transcriptional and protein levels in a time- and dose-dependent manner as measured by RT-PCR and Western blot analysis, respectively. These inductions were abolished by pretreatment of N-acetyl-cystein (NAC, 1~10 mM), but not by employing Tempol, a superoxide dismutase (SOD) mimetic (1~5 mM). As expected, enzymatic activity (~2 fold) determined by bilirubin formation assay and cGMP concentration (~6 fold) were significantly increased in BSP-treated cells. Based on the numerous evidences on the beneficial effects of HO-1 and our results, we investigated in vivo effects of BSP on the antihypertensive activity. The administration of BSP (1% in drinking water) significantly decreased mean blood pressure (BP) (from 218.6±6.99 to 190.0±3.42 mm Hg, p<0.01). This result indicates that BSP is strong inducer of HO-1 expression, which may be triggered by oxidative stress, and has anti-hypertensive activity.

여성관련개발지수와 모성 및 영아 사망률과의 관계

신미경 ( Mi Kyong Shin ),김한중 ( Han Jong Kim ),김모임 ( Mo Im Kim ),박은철 ( Eun Cheo Park ),박종연 ( Chong Yon Park ) 한국보건행정학회 2000 보건행정학회지 Vol.10 No.2

사염화탄소를 투여한 흰쥐에서 녹차 추출물이 간기능 개선 및 항섬유화에 미치는 영향

신미경(Mee-Kyung Shin),최명훈(Ming-Xun Cui),김현영(Hyun-Young Kim) 한국차학회 2013 한국차학회지 Vol.19 No.1

사염화탄소를 투여한 흰쥐에게 녹차 추출물을 급여하여 간기능 개선 및 항섬유화에 미치는 영향을 연구하였다. 1. 식이 섭취량, 체중 증가량 및 식이효율은 정상군에 비하여 대조군과 녹차 추출물 급여군이 유의적인 차이는 없었다. 2. 간 무게와 체중 당 간 무게의 비는 대조군에 비하여 녹차 추출물 급여군이 낮았으나 유의적인 차이는 없었다. 3. 혈청의 AST, ALT 활성 변화는 대조군에 비하여 녹차 추출물 급여군이 유의적으로 낮았고(p < 0.01), ALP 활성변화는 대조군에 비하여 녹차 추출물 급여군인 Ga군에서는 낮았으나 유의적인 차이는 없었고, Gb군에서는 유의적으로 낮았다(p < 0.05). HDL-cholesterol 수준은 대조군에 비하여 녹차 추출물 급여군이 높았으나 유의적인 차이는 없었고, LDL-cholesterol 수준은 대조군에 비하여 녹차 추출물 급여군이 낮았으나 유의적인 차이는 없었다. 4. 간 조직의 MDA 함량은 대조군에 비하여 녹차 추출물 급여군이 유의적으로 낮았고(p < 0.05), hydroxyproline 함량은 대조군에 비하여 녹차 추출물 급여군이 낮았으나 유의적인 차이는 없었다. 5. 간 조직의 형태학적 변화는 대조군에 비하여 녹차 추출물 급여군이 콜라겐의 증가와 지방변성과 지방적이 약하게 나타났다. 결론적으로 녹차 추출물은 흰쥐에 사염화탄소를 투여하여 간의 지질과산화에 의한 독성 유도시 혈청의 AST, ALT, ALP, HDL-cholesterol, LDL-cholesterol, 간 조직의 MDA와 hydroxyproline의 개선 경향 및 콜라겐 축적 억제, 간 조직 손상 보호를 통해 간기능 개선과 항섬유화 효과가 있는 것으로 판단되므로 이에 따른 보다 많은 연구가 이루어져야 할 것으로 사료된다. This study examined the hepatic functional improvement and anti-fibrotic effects of the water extracts of green tea. Male Sprague-Dawley rats were divided into four groups (normal, control, and two experimental subgroups(Ga and Gb)) and observed for 3 weeks. Liver fibrosis was induced in the rats by carbon tetrachloride (CCl₄) administration, with the exception of the normal group. With the exception of the normal and control group, the two experimental subgroups were fed water extracts of green tea. No significant differences were observed in the food intake, body weight gain or food efficiency ratio between the normal group and experimental group. The liver weight and the liver weight to body weight ratio decreased in the experimental group compared to the control group, but the difference was not significant. The serum levels of aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase was significantly lower in the experimental group than the control group. The levels of high density lipoprotein-cholesterol in serum increased in the experimental group compared to the control group, but the difference was not significant. The levels of low density lipoprotein-cholesterol in the serum decreased in the experimental group compared to the control group, but the difference was not significant. The malondialdehyde levels in the liver tissue were significantly lower in the experimental group than the control group. No significant differences in hydroxyproline in the liver tissue were observed between the experimental group and control group. Regarding the liver histology, weaker inflammation and fibrosis were observed in the experimental group compared to the control group. In conclusion, the water extracts of green tea help hepatic cells keep maintain their functions, restraining and protecting the liver from the impairments caused by CCl₄ administration, and can be effective as anti-fibrotic agents.

초등학교 수학의 교수를 위한 모바일 가상조작물 앱 분석

신미경(Mikyung Shin) 한국멀티미디어학회 2017 멀티미디어학회논문지 Vol.20 No.6

‘从’과 한국어격조사의대응관계및 제약조건 연구 - ‘에서’, ‘에게서’, ‘로’를 중심으로

신미경(Shin, Me-gyeong),유위(Liu, Wei) 한국중어중문학회 2020 中語中文學 Vol.- No.81

This paper considered the corresponding relation and constraint condition between Chinese preposition “从” and the Korean starting point case marker “에서”, “에게서”, “로”. In this paper,first we organized and reclassified the meaning items of Chinese “从” and Korean case marker “에서”, “에게서, “로”. Subsequently, we analyzed the responses and constraints of “从” and the Korean case marker. Observations in this paper confirmed that “从” can respond to “에게”, “에게서”, “로” in some cases, but there are certain constraints. Their correspondence can be summarized as follows: First, when indicating the starting point of the abode, “从” can respond to “에서” and not to “에게서”. Second, when indicating the starting point of time, “从” can respond to “에서” and not to “에게서”, “로”. Third, when indicating the starting point of the range, “从” is free to respond to “에서” and not to “에게서”, “로”. Fourth, when indicating a path, “从” can respond with “로”” and not with “에서” and “에게서”. Fifth, in the case of indicating a source, “从” can respond to “에서”.