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두경부 종양에서 99mTc - ( V ) - DMSA 영상술의 진단적 유용성
이규보(Kyu Bo Lee),이재태(Jae Tae Lee),김정균(Jeong Gyun Kim),배선근(Sun Kun Bae),박준식(June Sik Park),박인규(In Kyu Park),현동우(Dong Woo Hyun),이영학(Young Hak Lee),안병철(Byeong Cheal Ahn),최지용(Ji Yong Choi),손상균(Sang Gyun So 대한핵의학회 1995 핵의학 분자영상 Vol.29 No.4
N/A Introduction: Tc-99m-(V)-DMSA is a tumor seeking agent that has been used to image medullary carcinoma of thyroid, soft tissue sarcoma and lung cancer. This study was designed to assess the clinical role of Tc-99m-(V)-DMSA in the diagnosis of head and neck cancers. We has evaluated the diagnostic efficacy of planar and SPECT imaging using Tc-99m-(V)-DMSA. Patients and Method: Sixty-eight patients with head and neck mass were included in this study. All subjects were diagnosed by biopsy or surgery. Planar and SPECT images were obtained at 2 or 3 hour after intravenous injection of 740 MBq(20 mCi) Tc-99m-(V)-DMSA. Seventeen patients also underwent SPECT imaging using dual head camera. Results: The diagnostic sensitivity of Tc-99m-(V)-DMSA planar and SPECT imaging was 65% and 90%, and specificity was 80% and 66%, respectively. The sensitivity of planar imaging in squamous cell carcinoma was similar to overall sensitivity. Six metastatic lesion were first diagnosed by scintigraphy. But benign lesions such as Kikuchi syndrome, tuberculous lymphadenitis also revealed increased uptake. Conclusion: Tc-99m-(V)-DMSA imaging seems to be a promising method in the evaluation of patients with head and neck mass. We recommend SPECT imaging to delineate anatomic localization of the lesion.