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김민지 ( Minji Kim ),김현희 ( Hyun Hee Kim ),김효빈 ( Hyo-bin Kim ),나영호 ( Yeong-ho Rha ),박양 ( Yang Park ),성명순 ( Myongsoon Sung ),신윤호 ( Youn Ho Shin ),염혜영 ( Hye Yung Yum ),이경석 ( Kyung Suk Lee ),이용주 ( Yong Ju Le 대한천식알레르기학회 2021 Allergy Asthma & Respiratory Disease Vol.9 No.4
Allergic rhinitis (AR) is one of the most common allergic diseases characterized by stuffy nose, rhinorrhea, sneezing, and itching. Re-searchers have indicated an increase in the prevalence of AR and younger-age onset during the last few decades. The increasing burden of AR has caused many researchers to investigate time trends of the prevalence of AR and to identify its risk factors. The most commonly used epidemiological studies are cross-sectional ones such as the International Study of Asthma and Allergies in Childhood study and big data from National Health Insurance Service or National Health and Nutrition Examination Survey. How-ever, these studies have many limitations including recall bias, selection bias, and deficit of objective evaluation. Furthermore, cross- sectional studies cannot reflect new risk factors associated with the development of AR. New epidemiological studies will be needed to cover genetic factors, environmental changes, microbiomes, and lifestyles that are known to be risk factors for AR. Fur-ther studies will be needed to determine the prevalence, natural history, and risk factors of AR in order to advance our understand-ing of the pathophysiology, prevention, and management of comorbidities of AR. (Allergy Asthma Respir Dis 2021;9:203-207)
전윤홍 ( Yoon Hong Chun ),김민지 ( Minji Kim ),김효빈 ( Hyo-bin Kim ),나영호 ( Yeong-ho Rha ),박양 ( Yang Park ),박용민 ( Yong Mean Park ),성명순 ( Myongsoon Sung ),신윤호 ( Youn Ho Shin ),염혜영 ( Hye Yung Yum ),이경석 ( Kyung S 대한천식알레르기학회 2022 Allergy Asthma & Respiratory Disease Vol.10 No.2
Among allergic diseases of the Korean pediatric population, allergic rhinitis shows the most rapidly increasing prevalence. Its economic burden is substantial in many Asian countries including South Korea. This investigation of its risk factors aims to reduce the socioeconomic burden by blocking exposure of susceptible individuals to identified causes. However, the risk factors of allergic rhinitis varied considerably depending on the seasons, geographical locations, and populations involved. This review article primarily deals with studies on the risk factors for allergic rhinitis in Korean children that were published during the last 10 years and additionally investigates associated large scale international studies. Our investigation identified several single-nucleotide polymorphisms, inhalant allergens, pollution, tobacco smoke, chemicals, and family affluence as risk factors for allergic rhinitis. In contrast, breastfeeding, older sibling, and microbial diversity were protective factors against allergic rhinitis. This suggests that various genetic and environmental factors might affect the manifestation and presentation of allergic rhinitis complexly. These findings are beneficial as they can provide insights into modifiable risk factors that may hinder the development of allergic rhinitis. (Allergy Asthma Respir Dis 2022;10:73-79)