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Monofluorophosphate와 Chlorhexidine 및 Flavonoid배합세치제의 치면세균막형성억제효과와 구취감소효과에 관한 실용실험적 연구
김종배,백대일,문혁수,서현석,진보형 대한구강보건학회 1991 大韓口腔保健學會誌 Vol.15 No.2
n order to evaluate the effects of therapeutic toothpastes containing monofluorophosphate, Vitamine-E, Flavonoid, Chlorhexidine, on the inhibition of dental plaque formation, the authors had examined the oral status of 50 students aged twentieth. Then they were given with cosmetic toothpaste and therapeutic toothpaste in due sequence. At the same time, all students were given with straight handled mixed bristled toothbrush and directed to brush teeth with toothpaste and toothbrush offered. The patient hygiene performance were examined in the 7th day, after that they changed their toothpaste to another one. So, each of them could use 2 toothpastes for 7 days respectively. On the other hand, to evaluate the reducing effects of dentifrice containing chlorhexidine on the numbers of Streptococcus mutans, 11 adults aged twentieth were experimented. They used offered toothbrush and chlorhexidine dentifrice and cosmetic dentifrice for 1 week and 3 weeks. To collect data, every volunteers rinsed their mouth with 0.1% pepton solution, the rinsing solutions were inoculated into MSBagar plate, After 3days anaerobic incubation under the conditions of 10% H₂, 10% Co₂, 80% N₂, The colony forms were identified by 9 biochemical tests. While, to evaluate the malodor reducing efficiency, the authors analysed the volatile sulfur compounds from the breath after ingestion of garlic powder, 10 adults aged twentieth were examined. To obtained adequate data, expirating breath was collected into sampling loop, after ingestion of garlic powder, the subject cleansed the oral cavity by one of the designated methods and reevaluated at 2, 7, 12 and 17minutes after ingestion of garlic powder. Gas chromatographic techic was employed for the evaluation of volatile sulfur compounds in mouth air. The percent change in VSC concentration of air samples were calculated in relation to values of it after ingestion of garlic powder immediately. Thereafter, the data was compared statistically and discussed. The obtained results were as follows; 1. Therapeutic toothpastes inhibited plaque formation more effectively than cosmetic toothpaste. 2. After the use of therapeutic toothpaste containing MVFC, the numbers of Streptococcus mutans were decreased both 1 week(P<0.0l) and 3weeks(P<0.05). 3. Therapeutic toothpaste containing MVFC reduced more methyl mercaptan and allyl mercaptan(P<0.05) than control cosmetic toothpaste.
Calcium glycerophosphate와 Flavonoid 및 Vitamin - E 배합세치제의 치면세균막제거효과 및 구취제거효과에 관한 실용실험적 연구
김종배,서현석,진보형,송연희,신승철,이건수 대한구강보건학회 1991 大韓口腔保健學會誌 Vol.15 No.1
In order to evaluate the effect of a therapeutic toothpaste containing calcium glycerophosphate flavonoid and vitamin-E on the inhibition of dental plaque formation, the authors had examined the oral status of 96 students aged twentieth, divided into two groups, 48 in one control group were given with cosmetic toothpaste, 48 students in the other experimental group with therapeutic toothpaste containing CGP, Flavonoid, Vitamin-E. At the same time, all students were given with straight handled medium bristled toothbrush and directed to brush teeth with toothpaste and toothbrush offered. The patient hygiene performance were repeatedly examined in the 7th day, and 14th day. On the other hands, to evaluate the malodor reducing efficiency, the authors and analysed the volatile sulfur compounds from the breath after ingestion of garlic powder. 5 adults aged twentieth were examined. To obtained adequate data, expirating breath were collected into sampling loop, after ingestion of garlic powder, the subjects cleansed the oral cavity by one of the designated methods and reevaluated at 2, 7, 12 and 17 minutes after ingestion of garlic powder. Gas chromatographic technic was employed for the evaluation of volatile sulfur compounds in mouth air. The percentage change in VSC concentration of air samples were calculated in relation to values of it after ingestion of garlic powder immediately. Thereafter, the data was compared statistically and discussed. The obtained results were as follows; 1. Calcium glycerophosphate, flavonoid and vitamin-E containing toothpaste inhibited plaque formation more effectively than control cosmetic toothpaste(p<0.05). 2. Methyl mercaptan and allyl mercaptan were detected in the breath after ingestion of garlic powder. 3. Calcium glycerophosphate, flavonoid and vitamin-E containing toothpaste reduced more methyl mercaptan than control cosmetic toothpaste(p<0.05). 4. Calcium glycerophosphate, flavonoid and vitamin-E containing toothpaste reduced more allyl mercaptan than control cosmetic toothpaste(p<0.05) 5. Therapeutic toothpaste containing calcium glycerophosphate, flavonoid and vitamin-E increased the effects of plaque formation inhibition & malodor elimination.