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김종훈(Jonghun Kim),변주영(Juyoung Byon),이민영(Minyeong Lee),송진경(Jinkyung Song),이영은(Youngeun Lee),임지현(Jihyun Yim),유인삼(Insam Yoo),김은희(Eunheui Kim) 전남대학교 수산과학연구소 2002 수산과학연구소논문집 Vol.11 No.-
The distributions of drug resistance bacteria were investigated in 28 sites of the southern coastal sea water of korea. Drug resistance bacteria were isolated using the sea water nutrient agar media containing the 10㎍/㎖ of ampicillin(AM), 25 ㎍/㎖ of streptomycin(SM), and 250㎍/㎖ of sulfonamide(SA). Over 30% of total bacteria showed AM and SM resistance in 8 and 7 sampling sites, respectively but SA resistance only in 2 sites. Two hundreds and ninty isolates were divided to 6 types of resistance pattern from 1 to 6 kind of drugs. Over 60% of the resistance bacteria showed multiple resistant to more than 3 drugs. About 70% of multiple drug resistance bacteria had the transferable resistance marker and the markers were AM, kanamycin, oxytetracyclin resistance. The resistance bacteria to oxytetracycline or oxolinic acid appeared around fish farms developed well.