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백승주 ( Seung Ju Back ),이경문 ( Kyung Moon Lee ),조아영 ( Ah Young Cho ),이영 ( Young Lee ),서영준 ( Young Joon Seo ),박장규 ( Jang Kyu Park ),이증훈 ( Jeung Hoon Lee ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.6
The amniotic band syndrome is a collection of fetal malformations associated with fibrous band that appears to entangle or entrap various fetal part, in utero, leading to deformation, malformation or disruption. Its pathogenesis has been debated in the literature for many years. The associated anomalies vary from minor limb anomalies to major craniofacial defects and visceral defects. We experienced a case of limb anomalies due to amniotic band and present the findings with a brief review of literature. (Korean J Dermatol 2008;46(6):815∼817)
백승주 ( Seung Ju Back ),황철 ( Chul Hwang ),서영준 ( Young Joon Seo ),이증훈 ( Jeung Hoon Lee ),박장규 ( Jang Kyu Park ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.1
Trichoblastoma is a benign cutaneous neoplasm that consists of follicular germinative cells. There have only been a few case reports describing the malignant counterpart of trichoblastoma. We report trichoblastic neoplasms that show histological features of malignancy. The histological sections revealed locally aggressive neoplasms showing prominent differentiation towards hair germ and follicular sheath with formation of papillary mesenchymal bodies and follicular bulb-like structures. The tumor was widely excised with a clear margin. No sign of recurrence has been noted 1 year later. (Korean J Dermatol 2008;46(1):94∼96)
화농성 육아종의 임상양상을 보인 간세포암 피부 전이 1예
백승주 ( Seung Ju Back ),김보중 ( Bo Joong Kim ),서영준 ( Young Joon Seo ),박장규 ( Jang Kyu Park ),이증훈 ( Jeung Hoon Lee ) 대한피부과학회 2007 大韓皮膚科學會誌 Vol.45 No.5
Skin lesions can sometimes be the presenting sign of metastatic cancers. We report a case of skin metastasis resembling pyogenic granuloma from hepatocellular carcinoma, which is a common malignancy in Korea. A 79-year-old male presented with a 1 month history of a dark-reddish nodule on his left cheek, which was thought to be pyogenic granuloma. On histopathologic examination, it was composed of tumor cells and intervening sinusoids and therefore showed characteristics of hepatocellular carcinoma. We confirmed hepatocellular carcinoma upon abdomen computer tomography. We present this case along with a review of previous reports of cutaneous metastasis from hepatocellular carcinoma. (Korean J Dermatol 2007;45(5):512~514)
백승주 ( Seung Ju Back ),임명 ( Myung Im ),김창덕 ( Chang Deok Kim ),서영준 ( Young Joon Seo ),이증훈 ( Jeung Hoon Lee ),박장규 ( Jang Kyu Park ) 대한피부과학회 2007 大韓皮膚科學會誌 Vol.45 No.9
Background: Acute diffuse alopecia areata (AA) was described as a unique AA which mimics anagen effluvium, or in which the initial hair loss is diffuse and followed by total denudation of scalp within several weeks or months. In spite of its peculiar clinical feature, there was neither further characterization nor known effective treatment for this form of AA. Objective: To evaluate the characteristic clinical findings of acute diffuse AA and confirm the effect of high dose methyl prednisolone therapy. Methods: The medical records of 13 patients with acute diffuse AA between January 2002 and April 2006 at the Department of Dermatology, Chungnam National University Hospital were reviewed. All patients were treated with high dose methylprednisolone therapy. Results: Of the 13 patients who completed the study, 8 patients (61.5%) were male and 5 patients (38.5%) were female. The mean age was 29.6 years old. The progress of hair loss stopped 2.4 weeks on average after initial treatment and newly emerging hairs were recognized 4.1 weeks on average after initial treatment. 84.6% (11/13) of patients showed terminal hair growth, and 46.2% (6/13) of patients completely responded to this therapy. Conclusion: Acute diffuse alopecia areata can occur in male as well as in female patients. High dose methyl-prednisolone therapy appears to be effective in patients with rapidly progressing acute diffuse alopecia areata to prevent the progression of the disease. (Korean J Dermatol 2007;45(9):884∼889)
백승주 ( Seung Ju Back ),박영옥 ( Young Ok Park ),김계정 ( Kae Jeung Kim ),김창덕 ( Chang Deok Kim ),서영준 ( Young Joon Seo ),이증훈 ( Jeung Hoon Lee ),박장규 ( Jang Kyu Park ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.5
Background: Hair constitutes an integral part of our self and our self-identity, which is why hair loss may cause a broad range of psychological problems related to our identity. However, the association between quality of life (QOL) in alopecia areata (AA) patients and their clinical characteristics has not yet been investigated in Korea. Objective: The purpose of this study is to compare the QOL in patients with AA and healthy controls by using Hairdex scale. The relationship between their QOL and their clinical characteristics will be investigated. Methods: 102 AA patients and 82 healthy controls were recruited in this study and compared by use of Hairdex. Correlation analysis was performed to examine the relationship between the QOL and the clinical characteristics of patients with AA. Results: The total Hairdex scores and all domain scores, except those of the symptomatic domain, of the Hairdex scales in AA were higher than those of the healthy controls. Clinical characteristics, including the age, disease duration, AA type, AA area, treatment satisfaction, treatment history, anxiety and depression, showed significant correlation with QOL. Of these characteristics, the depression and treatment satisfaction showed strong association with QOL. Conclusion: AA can a impair patient`s quality of life and has a significant psychological impact. (Korean J Dermatol 2008;46(5):578∼586)
황철 ( Chul Hwang ),백승주 ( Seung Ju Back ),최대경 ( Dae Kyoung Choi ),서영준 ( Young June Seo ),박장규 ( Jang Kyu Park ),이증훈 ( Jeung Hoon Lee ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.9
We report a case of thermal keratosis with erythema ab igne which occurred on the dorsal side of a patient`s left hand due to chronic exposure to infrared rays. A 62-year-old male presented with reticular hyperpigmentation on the dorsal side of his left hand and left knee along with multiple hyperkeratotic nodules on the dorsal side of his left hand without any symptoms. He had a hobby of playing internet games with a heater on his left side. A skin biopsy of the hyperkeratotic lesion showed hyperkeratosis and acanthosis in the epidermis. The dermis revealed many elastic fibers and superficial perivascular monocytic infiltration. The patient was diagnosed with thermal keratosis and erythema ab igne due to his history of chronic infrared exposure, distinctive clinical characteristics and the biopsy results. The application of topical steroid with the recommendation to cease exposure to heaters resulted in the almost disappearance of the papules and a little restoration of the skin color. (Korean J Dermatol 2007;45(9):926∼929)
후천성 양측성 오타 모반양 반점과 이토 모반양 반점을 동반한 전신성 후천성 멜라닌 세포증
이경문 ( Kyung Moon Lee ),백승주 ( Seung Ju Back ),이영 ( Young Lee ),서영준 ( Young Joon Seo ),박장규 ( Jang Kyu Park ),이증훈 ( Jeung Hoon Lee ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.11
Dermal melanocytosis is histologically characterized by the presence of ectopic melanocytes in the dermis. Mongolian spots, nevus of Ota, nevus of Ito and blue nevus are the most common types and these are usually present at birth or in early childhood. However, it has been reported that several types of dermal melanocytosis could appear in adult life. We report here on an unusual case of acquired dermal melanocytosis occurring in a 51 year-old female. She had bilaterall brownish or slate-bluish pigmented patches on the face and the posterior auricular, supraclavicular, scapular and back areas. The skin biopsy specimen taken from the upper back revealed scattered, darkly pigmented, spindle-shaped cells and dendritic cells containing abundant golden brown pigment in the dermis. (Korean J Dermatol 2008; 46(11): 1543∼1547)