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백승복(白承福),장기봉(張起峰),김경호(金慶浩),박봉조(朴凰祚) 대한바이러스학회 1971 Journal of Bacteriology and Virology Vol.1 No.1
The purpose of this report is to present the seasonal differences of Japanese Encephalitis virus infection ate and the aspect of viremia state among the 30 sentinel piglets (10 piglets each in Seoul, Pusan and Sintaein) and Japanese Encephalitis virus isolations were attempted to each piglets and also H-I antibody iters were observed with regular intervals. The epidemiological relationship among epidemics in human, Culex tritaeniorhychus mosquitoes population and antibody distribution of the pig sera collected from slaugbter houses and sentinel piglets were observed. The obtained results were as follows: 1) H-I antibody titer of sentinel pigs Seoul area: Survey was carried out bleeding from Juae to September. H-I antibody titer showed 0% of positive rate. It was considered that the study place was not suitable. Pusan area: June 1: positive rate-78% (It was considered as maternal immunity) August 8: positive rate-0% (No more maternal immunity showed) August 14: positive rate 90% August 20: positive rate-100% 2) Antibody survey of pigs from slaughter houses. H-I antibody rate showed as follows: Seoul area: August 6-24% August 21-56% August 28-92% Pusan area: Auguat 20-37.5% August 26-100% Chola-puk Do: August 1-12.5% August 22-100% 3) J.E. virus isolation from a sentinel pig J.E. virus was isolated from one pig out of 10 sentinel pigs in Pusan on August 6, 1971. The results of antigenic analysis on isolated J.E. virus strain (SP 80671) through the test of hemagglutination inhibition reaction are more similar to JaGAr 01 than Nakayama-NIH (Table 5). Optimal pH range is that Nakayama-NIH is 6. 4, JaGAr 01 is 6. 6 and SP 80671 is 6.4-6.6(Table 6) 4) It is learnt from the study in Pusan area that soon after reaching the peak of population density of C.t. adults, pigs appeared vireiga and J.E. antibody, and then human infection of J.E. virus followed. It may be said that forecasting period for prevention J.E. in human is when pig antibody rate reached 50%. 5) J.E. virus was not isolated from C.t. mosquitoes (25 pools) collected from Seoul, Pusan and Chola Puk-Do.